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  1. 6501
    Growth tradeoffs produce complex microbial communities on a single limiting resource
    “...Higher-order interactions occur when one species mediates the interaction between two others. Here...”
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  2. 6502
    Supramammillary glutamate neurons are a key node of the arousal system
    “... but their possible role in mediating wakefulness is not known. Here the authors elucidate the distinct functional...”
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  3. 6503
    Escherichia coli adhesion portion FimH functions as an adjuvant for cancer immunotherapy
    “...-dependent adjuvant effect of FimH, an E. coli adhesin, in promoting dendritic cell mediated-T cell...”
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  4. 6504
    Force-dependent allostery of the α-catenin actin-binding domain controls adherens junction dynamics and functions
    “...Cell-cell adhesion mediated by catenin-cadherin complexes plays a critical role in translating...”
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  5. 6505
    Selective reduction and homologation of carbon monoxide by organometallic iron complexes
    “...Metal-mediated activation of CO for C-C coupling reactions is a valuable approach to carbon...”
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  6. 6506
    Engineering Na+-layer spacings to stabilize Mn-based layered cathodes for sodium-ion batteries
    “... cathodes in batteries. Here, the authors report a water-mediated strategy to mitigate the phase transitions...”
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  7. 6507
    The P-type ATPase transporter ATP7A promotes angiogenesis by limiting autophagic degradation of VEGFR2
    “... by limiting autophagy-mediated degradation of VEGFR2, which enhances reparative neovascularization....”
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  8. 6508
    Characteristic rotational behaviors of rod-shaped cargo revealed by automated five-dimensional single particle tracking
    “... behaviors of nanocargos during clathrin-mediated endocytosis and intracellular transport....”
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  9. 6509
    Visible light-promoted CO2 fixation with imines to synthesize diaryl α-amino acids
    “... in sustainable chemistry. Here, the authors show a visible light-mediated hydrocarboxylation of ketimines...”
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  10. 6510
    Thick filament mechano-sensing is a calcium-independent regulatory mechanism in skeletal muscle
    por L. Fusi, E. Brunello, Z. Yan, M. Irving
    Publicado 2016
    “... in addition to the well-known thin filament-mediated calcium signalling pathway. Here the authors provide...”
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  11. 6511
    Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation
    “... show that the ubiquitin ligase MKRN1 binds to AMPK and mediates its ubiquitination and degradation...”
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  12. 6512
    Non-homologous DNA increases gene disruption efficiency by altering DNA repair outcomes
    “...CRISPR-Cas9 mediated gene editing has begun to revolutionize molecular biology, but editing...”
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  13. 6513
    Gelsolin dysfunction causes photoreceptor loss in induced pluripotent cell and animal retinitis pigmentosa models
    “... and mouse knockouts that RPGR mediates actin dynamics in photoreceptors via the actin-severing protein...”
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  14. 6514
    Epidermal growth factor receptor signaling uncouples germ cells from the somatic follicular compartment at ovulation
    “... loss of filopodia oocyte adhesion, and Arp2/3 mediated retraction of granulosa cell filopodia....”
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  15. 6515
    Regulation of the linear ubiquitination of STAT1 controls antiviral interferon signaling
    “... the authors show that this mechanism is effective in inhibiting STAT1-mediated interferon signaling...”
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  16. 6516
    Outward open conformation of a Major Facilitator Superfamily multidrug/H+ antiporter provides insights into switching mechanism
    “...The multidrug resistance transporter mediated efflux of antibiotics from the bacterial cytoplasm...”
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  17. 6517
    A rice Serine/Threonine receptor-like kinase regulates arbuscular mycorrhizal symbiosis at the peri-arbuscular membrane
    “...The peri-arbuscular membrane (PAM) mediates mutually-beneficial nutrient exchange between plants...”
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  18. 6518
    Docking of acetyl-CoA carboxylase to the plastid envelope membrane attenuates fatty acid production in plants
    “...In plants, light-dependent activation fatty acid synthesis (FAS) is mediated in part by acetyl-CoA...”
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  19. 6519
    miR-802 regulates Paneth cell function and enterocyte differentiation in the mouse small intestine
    “... and glucose absorption, enhances Paneth cell function by increasing Tmed9-mediated defensin secretion...”
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  20. 6520
    Visualizing the Hidden Half: Plant-Microbe Interactions in the Rhizosphere
    “... intra- and interkingdom interactions, including metabolite exchange between plants and soil mediated...”
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