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  1. 6541
    E3 ligase FBXW7 is critical for RIG-I stabilization during antiviral responses
    “... the authors show that, upon virus infection, FBXW7 interacts with RIG-I and inhibits ubiquitin-mediated...”
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  2. 6542
    Adsorbate-induced lifting of substrate relaxation is a general mechanism governing titania surface chemistry
    “...) that strongly bonded adsorbates lift surface relaxations, leading to substrate-mediated interaction between...”
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  3. 6543
    Graphene-based synthetic antiferromagnets and ferrimagnets
    “... graphene-mediated perpendicular antiferromagnetic coupling between Fe and Co layers in a Fe/graphene/Co...”
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  4. 6544
    Structural basis of actin monomer re-charging by cyclase-associated protein
    “... and their CAP–actin complex structure reveals the molecular mechanism of CAP-mediated actin nucleotide exchange....”
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  5. 6545
    AWD regulates timed activation of BMP signaling in intestinal stem cells to maintain tissue homeostasis
    “... by ISCs involves BMP Type I receptor Tkv protein stabilization along with AWD mediated internalization...”
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  6. 6546
    RNF167 activates mTORC1 and promotes tumorigenesis by targeting CASTOR1 for ubiquitination and degradation
    “... dysregulated in cancers. Here the authors show that AKT and E3 ubiquitin ligase RNF167 mediate CASTOR1...”
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  7. 6547
    Microglial P2Y12 is necessary for synaptic plasticity in mouse visual cortex
    “... are important mediators of ocular dominance plasticity (ODP). Microglia respond to monocular deprivation during...”
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  8. 6548
    Initiation and amplification of SnRK2 activation in abscisic acid signaling
    “... activation of SnRK2s is achieved by B2 and B3 RAF kinase-mediated phosphorylation of the activation loop...”
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  9. 6549
    The Hippo signalling pathway maintains quiescence in Drosophila neural stem cells
    “... is unclear. Here, Ding et al. show that quiescence of NSCs is mediated by cell-contact inhibition via...”
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  10. 6550
    Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity
    “... strong modifier of TDP-43-mediated neurodegeneration through the Ell transcriptional elongation complexes...”
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  11. 6551
    PI3Kδ hyper-activation promotes development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner
    “...Antibody mediated immune responses to Streptococcus pneumoniae are crucial for the immune response...”
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  12. 6552
    Inositol treatment inhibits medulloblastoma through suppression of epigenetic-driven metabolic adaptation
    “..., the authors demonstrate that the BMI1High/CHD7Low signature mediates metabolic adaptation in G4 MB...”
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  13. 6553
    Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metastasis driver genes
    “... of migratory phenotypes and show that one of the regulators, PRPF4B, mediates metastasis in TNBC in mice....”
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  14. 6554
    The actin cytoskeletal architecture of estrogen receptor positive breast cancer cells suppresses invasion
    “... of Suppressive Cortical Actin Bundles that can inhibit motility dynamics through EVL-mediated actin cytoskeletal...”
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  15. 6555
    The synaptic receptor Lrp4 promotes peripheral nerve regeneration
    “..., the authors show that regenerating axons follow pioneer axons and this process is mediated by lipoprotein...”
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  16. 6556
    High-throughput phenotypic screen and transcriptional analysis identify new compounds and targets for macrophage reprogramming
    “... and pathways mediating these effects....”
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  17. 6557
    Survival of pancreatic cancer cells lacking KRAS function
    “... and that PI3K signalling may have an important role in mediating tumor growth following KRAS inhibition....”
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  18. 6558
    Muscle-specific CRISPR/Cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for Duchenne muscular dystrophy
    “...CRISPR/Cas9-mediated gene editing is an emerging strategy to treat Duchenne muscular dystrophy...”
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  19. 6559
    Oxidation of F-actin controls the terminal steps of cytokinesis
    “... is recruited by Rab35 and induces oxidation-mediated depolymerization of actin, which is required to recruit...”
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  20. 6560
    CRL4Wdr70 regulates H2B monoubiquitination and facilitates Exo1-dependent resection
    “... as part of the CRL4 complex to promote ubiquitination of H2B and allow Exo1-mediated resection....”
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