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  1. 6581
    Bacteriophage T5 tail tube structure suggests a trigger mechanism for Siphoviridae DNA ejection
    “...Host cell recognition is mediated by the phage tail tip proteins, which then triggers viral genome...”
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  2. 6582
    Dual functions of Aire CARD multimerization in the transcriptional regulation of T cell tolerance
    “...The transcription factor Aire mediates tissue-specific antigen expression in the thymus for T cell...”
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  3. 6583
    Local auxin competition explains fragmented differentiation patterns
    “... by preventing cell fate bistability emerging from AUX1-mediated competition for auxin between neighboring cells....”
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  4. 6584
    VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination
    “... differentiation and thereby myelination, an effect mediated by downstream CD69 signalling....”
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  5. 6585
    Sequential forward and reverse transport of the Na+ Ca2+ exchanger generates Ca2+ oscillations within mitochondria
    “...Mitochondrial Ca2+ homoeostasis is tightly regulated and export of Ca2+ is mediated by an Na+Ca2...”
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  6. 6586
    RdDM-independent de novo and heterochromatin DNA methylation by plant CMT and DNMT3 orthologs
    “... unclear. Here, the authors show that DNMT3s are persistent through plant evolution and mediates both de...”
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  7. 6587
    Resistance to TGFβ suppression and improved anti-tumor responses in CD8+ T cells lacking PTPN22
    “...TGFβ secretion in the tumor microenvironment inhibits T cell-mediated anti-tumor immune responses...”
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  8. 6588
    Combinatorial metabolic engineering using an orthogonal tri-functional CRISPR system
    “... sequentially in a high labor, low-throughput manner. Here, the authors use CRISPR-mediated gene activation...”
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  9. 6589
    A Mycobacterium tuberculosis surface protein recruits ubiquitin to trigger host xenophagy
    “...Ubiquitin (Ub)-mediated xenophagy is important in defense against Mycobacterium tuberculosis (Mtb...”
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  10. 6590
    Subtomogram averaging of COPII assemblies reveals how coat organization dictates membrane shape
    “...The COPII coat assembles in two concentric layers and mediates protein export from the endoplasmic...”
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  11. 6591
    Trpm5 channels encode bistability of spinal motoneurons and ensure motor control of hindlimbs in mice
    “...The authors show that Trpm5, but not Trpm4, is the main Na+ -permeant channel mediating the warmth...”
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  12. 6592
    The folate cycle enzyme MTHFD2 induces cancer immune evasion through PD-L1 up-regulation
    “... enzyme MTHFD2 stimulates PD-L1 expression impairing T cell-mediated cytotoxicity and promoting...”
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  13. 6593
    The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms
    “... of CaMKII is required for long-term plasticity and basal AMPA receptor-mediated transmission....”
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  14. 6594
    HDAC3 maintains oocyte meiosis arrest by repressing amphiregulin expression before the LH surge
    “..., which is mediated by EGF-like growth factors. Here, the authors show that HDAC3 inhibits mouse oocyte...”
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  15. 6595
    Global discovery of lupus genetic risk variant allelic enhancer activity
    “... to identify risk variants with allelic enhancer activity mediated through transcription factor binding....”
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  16. 6596
    Colossal tunability in high frequency magnetoelectric voltage tunable inductors
    “... to 10 MHz with tunability over 750% via strain mediated magnetoelectric effect and magnetocrystalline...”
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  17. 6597
    COPS5 amplification and overexpression confers tamoxifen-resistance in ERα-positive breast cancer by degradation of NCoR
    “...The corepressor NCoR is required for tamoxifen-mediated ERα-dependent transcriptional repression...”
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  18. 6598
    p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage
    “... are largely unexplored. Here, the authors show that UV light triggers p38-MK2-mediated phosphorylation...”
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  19. 6599
    UPF1-like helicase grip on nucleic acids dictates processivity
    “...UPF1 is a highly processive helicase that plays an essential role in nonsense-mediated mRNA decay...”
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  20. 6600
    Rapid host strain improvement by in vivo rearrangement of a synthetic yeast chromosome
    “...-mediated Evolution (SCRaMbLE) system into their synthetic chromosomes. Here the authors use SCRaMbLE...”
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