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  1. 6661
    G Protein–Coupled Estrogen Receptor 30 Reduces Transverse Aortic Constriction–Induced Myocardial Fibrosis in Aged Female Mice by Inhibiting the ERK1/2 -MMP-9 Signaling Pathway
    “... cardiovascular diseases. Previous studies have revealed that ERK1/2-mediated MMP-9 signaling was involved...”
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  2. 6662
    Mindfulness-Based Stress Reduction Increases Mental Wellbeing and Emotion Regulation During the First Wave of the COVID-19 Pandemic: A Synchronous Online Intervention Study
    “..., was not found to be affected by the program. A mediation analysis revealed that the effect of the intervention...”
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  3. 6663
    Structure of human cytomegalovirus virion reveals host tRNA binding to capsid-associated tegument protein pp150
    “... with the virion’s capsid-bound tegument protein, pp150. tRNA recruitment is mediated by the interactions specific...”
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  4. 6664
    Nuclear transporter Importin-13 plays a key role in the oxidative stress transcriptional response
    “...Importin superfamily member IPO13 mediates nuclear transport bidirectionally. Here the authors...”
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  5. 6665
    Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape
    “... and EBV-mediated effects converging on NF-κB activation and immune escape and identify targetable...”
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  6. 6666
    AXL confers cell migration and invasion by hijacking a PEAK1-regulated focal adhesion protein network
    “..., the authors show that AXL activation can control focal adhesion dynamics via PEAK1 and that AXL-mediated PEAK1...”
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  7. 6667
    CRISPR-Cas9 effectors facilitate generation of single-sex litters and sex-specific phenotypes
    “..., leading to wasted resources and ethical considerations. Here the authors develop a CRISPR/Cas9 mediated...”
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  8. 6668
    Procr-expressing progenitor cells are responsible for murine ovulatory rupture repair of ovarian surface epithelium
    “...The ovary is covered by a surface epithelium (OSE) and cells mediating its repair post ovulation...”
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  9. 6669
    Structural basis for Ca2+-dependent activation of a plant metacaspase
    “...Plant metacaspases mediate immune response following activation by Ca2+. Here, via crystallography...”
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  10. 6670
    The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication
    “... junction protein Connexin 43 in vivo and ACKR3-mediated inhibition of astrocyte gap junctional...”
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  11. 6671
    Sumoylation of RORγt regulates TH17 differentiation and thymocyte development
    “...-mediated sumoylation that stabilize the interaction with SRC1 and KAT2A, to enhance the transcriptional...”
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  12. 6672
    Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing
    “... mediators of EGFR TKI resistance....”
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  13. 6673
    BK channel inactivation gates daytime excitability in the circadian clock
    “...BK potassium channels have been previously shown to mediate SCN circadian firing, although...”
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  14. 6674
    Ccl2/Ccr2 signalling recruits a distinct fetal microchimeric population that rescues delayed maternal wound healing
    “... to injury sites, where they mediate repair, but how this is regulated is unclear. Here, the authors show...”
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  15. 6675
    Single-electron induced surface plasmons on a topological nanoparticle
    “... a surface charge layer that screens the particle, mediating interaction between bulk phonons...”
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  16. 6676
    Arf6 controls retromer traffic and intracellular cholesterol distribution via a phosphoinositide-based mechanism
    “... in endosomes due to defects in phosphoinositide-dependent retromer-mediated trafficking of CI-M6PR and NPC2....”
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  17. 6677
    Structural basis for perception of diverse chemical substances by T1r taste receptors
    “...Nutrients taste perception is mediated by T1r receptors that discriminate specific tastes among...”
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  18. 6678
    Positioning of nucleosomes containing γ-H2AX precedes active DNA demethylation and transcription initiation
    “... containing γ-H2AX, which is required for repair-mediated DNA demethylation and transcription....”
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  19. 6679
    Intestinal-derived FGF15 protects against deleterious effects of vertical sleeve gastrectomy in mice
    “...The mechanisms that mediate the effects of weight loss surgeries such as vertical sleeve...”
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  20. 6680
    Molecular basis for the inhibition of the methyl-lysine binding function of 53BP1 by TIRR
    “... processes. Here the authors give mechanistic insights into how TIRR mediates suppression by solving...”
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