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  1. 11621
    FKBP52 overexpression accelerates hippocampal-dependent memory impairments in a tau transgenic mouse model
    “... with previous studies, our findings suggest that FKBP52 may sensitize neurons to tau-mediated dysfunction via...”
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  2. 11622
    Inhibition of the ATP synthase sensitizes Staphylococcus aureus towards human antimicrobial peptides
    “.... Administration of the ATP synthase inhibitor, resveratrol, sensitizes S. aureus towards hBD4-mediated killing...”
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  3. 11623
    Compensatory Vasodilator Mechanisms in the Ophthalmic Artery of Endothelial Nitric Oxide Synthase Gene Knockout Mice
    “... metabolites of the 12-lipoxygenase pathway were key mediators in activating the inwardly rectifying potassium...”
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  4. 11624
    Targeting primary acute myeloid leukemia with a new CXCR4 antagonist IgG1 antibody (PF-06747143)
    “...Abstract The chemokine receptor CXCR4 mediates cell anchorage in the bone marrow (BM...”
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  5. 11625
    Hydrocortisone-induced parkin prevents dopaminergic cell death via CREB pathway in Parkinson’s disease model
    “...-activated parkin expression was mediated by CREB pathway since gRNA to CREB abolished hydrocortisone’s...”
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  6. 11626
    Mutational profile of rare variants in inflammasome-related genes in Behçet disease: A Next Generation Sequencing approach
    “...Abstract Behçet’s disease (BD) is an immune-mediated systemic disorder with a well-established...”
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  7. 11627
    The type IV pilus assembly ATPase PilB functions as a signaling protein to regulate exopolysaccharide production in Myxococcus xanthus
    “..., is required for this T4P-mediated motility in M. xanthus as the putative trigger of T4P retraction...”
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  8. 11628
    Fibroblastic reticular cells of the lymphoid tissues modulate T cell activation threshold during homeostasis via hyperactive cyclooxygenase-2/prostaglandin E2 axis
    “... cultured without FRCs. Different from T cell dysfunction, this FRC-mediated suppression is surmountable...”
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  9. 11629
    Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk alleles
    “... in the immunopathogenesis of T-cell mediated drug hypersensitivity syndromes. Nevirapine (NVP), is an HIV-1 antiretroviral...”
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  10. 11630
    Biogenesis of Pro-senescent Microparticles by Endothelial Colony Forming Cells from Premature Neonates is driven by SIRT1-Dependent Epigenetic Regulation of MKK6
    “...), mediating a paracrine induction of senescence in naïve endothelial cells. SIRT1 level inversely correlated...”
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  11. 11631
    An extremely high dietary iodide supply forestalls severe hypothyroidism in Na+/I− symporter (NIS) knockout mice
    “...Abstract The sodium/iodide symporter (NIS) mediates active iodide (I−) accumulation in the thyroid...”
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  12. 11632
    The PDK1 Inhibitor Dichloroacetate Controls Cholesterol Homeostasis Through the ERK5/MEF2 Pathway
    “... human hepatocytes and two different mouse models. This effect is mediated by transcriptional activation...”
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  13. 11633
    Splice variants as novel targets in pancreatic ductal adenocarcinoma
    “... that were also seen in transcriptome differential expression (DE) analysis, Fc gamma receptor-mediated...”
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  14. 11634
    Bifidobacterium pseudocatenulatum LI09 and Bifidobacterium catenulatum LI10 attenuate D-galactosamine-induced liver injury by modifying the gut microbiota
    “... results indicate that the liver protection effects might be mediated through gut microbiota modification...”
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  15. 11635
    Phytochromobilin deficiency impairs sugar metabolism through the regulation of cytokinin and auxin signaling in tomato fruits
    “... in mediating the negative impact of PΦB deficiency on fruit sink strength and chloroplast formation. PΦB...”
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  16. 11636
    ‘Cold shock’ increases the frequency of homology directed repair gene editing in induced pluripotent stem cells
    “... complementary oligos. Our protocol represents an efficient method for making CRISPR-mediated, specific DNA...”
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  17. 11637
    Fungus-derived hydroxyl radicals kill hepatic cells by enhancing nuclear transglutaminase
    “... pharmacological and genetic approaches demonstrated that this phenomenon was mediated partly by the production...”
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  18. 11638
    Defects in autophagosome-lysosome fusion underlie Vici syndrome, a neurodevelopmental disorder with multisystem involvement
    “.... To investigate the function of EPG5, siRNA based EPG5 knock-down, and CRISPR/Cas9 mediated EPG5 knock-out HeLa...”
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  19. 11639
    Pioglitazone Enhances Cytosolic Lipolysis, β-oxidation and Autophagy to Ameliorate Hepatic Steatosis
    “... cells. Our results demonstrated that pioglitazone attenuating the hepatic steatosis may be mediated...”
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  20. 11640
    Adeno-associated virus 2/9 delivery of Cre recombinase in mouse primary afferents
    “... the virus was administered at 2 weeks of age. Additionally, the virus-mediated delivery of the Cre-GFP...”
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