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  1. 12341
    ISL1 directly regulates FGF10 transcription during human cardiac outflow formation.
    “... the FGF10 first intron. ChIP and EMSA demonstrated its direct occupation by ISL1. Transcription mediated...”
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  2. 12342
    Brainstem respiratory oscillators develop independently of neuronal migration defects in the Wnt/PCP mouse mutant looptail.
    “... mediating an essential physiological function....”
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  3. 12343
    Premature senescence and increased TGFβ signaling in the absence of Tgif1.
    “... stress. Additionally, we show that Tgif1 null MEFs are more sensitive to TGFβ-mediated growth inhibition...”
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  4. 12344
    Overexpression of protochlorophyllide oxidoreductase C regulates oxidative stress in Arabidopsis.
    “.... Reduced protochlorophyllide content in PORCx plants released the protochlorophyllide-mediated feed-back...”
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  5. 12345
    3,3'-Diindolylmethane exhibits antileukemic activity in vitro and in vivo through a Akt-dependent process.
    “... Akt construct prevented DIM-mediated caspase activation, Mcl-1 down-regulation, JNK activation...”
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  6. 12346
    Two component systems: physiological effect of a third component.
    “...Signal transduction systems mediate the response and adaptation of organisms to environmental...”
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  7. 12347
    The effect of arrestin conformation on the recruitment of c-Raf1, MEK1, and ERK1/2 activation.
    “...-3A, a mimic of the receptor-bound conformation. Both rescue arrestin-mediated ERK1/2/activation...”
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  8. 12348
    A powerful method for transcriptional profiling of specific cell types in eukaryotes: laser-assisted microdissection and RNA sequencing.
    “... and is largely mediated by gene expression patterns specific to individual cells and tissues. A spatially...”
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  9. 12349
    Overexpression of cytokinin dehydrogenase genes in barley (Hordeum vulgare cv. Golden Promise) fundamentally affects morphology and fertility.
    “.... In addition, two selected CKX genes were used for stable, Agrobacterium tumefaciens-mediated transformation...”
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  10. 12350
    Exploring the efficacy of endoscopic ventriculostomy for hydrocephalus treatment via a multicompartmental poroelastic model of CSF transport: a computational perspective.
    “... permeability for the CSF compartment. This was done in order to account for the Aquaporin-4-mediated swelling...”
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  11. 12351
    Social environment influences performance in a cognitive task in natural variants of the foraging gene.
    “... different strain) in rovers, but not in sitters. These results suggest that for mediates social learning...”
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  12. 12352
    Serotonin is a key factor for mouse red blood cell survival.
    “... is not mediated through activation of a classical pharmacological pathway as no 5-HT receptors were detected...”
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  13. 12353
    Contact hypersensitivity to oxazolone provokes vulvar mechanical hyperalgesia in mice.
    “... conceptual advances in immunology and chronic pain. Hapten-mediated contact hypersensitivity reactions...”
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  14. 12354
    Conformational analysis of isolated domains of Helicobacter pylori CagA.
    “..., suggesting that the multimerisation of CagA observed in infected cells is likely to be mediated not by CagA...”
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  15. 12355
    Distribution of CD4(pos) -, CD8(pos) - and regulatory T cells in the upper and lower gastrointestinal tract in healthy young subjects.
    “...The gastrointestinal immune system is involved in the development of several autoimmune-mediated...”
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  16. 12356
    Curcumin alleviates neuropathic pain by inhibiting p300/CBP histone acetyltransferase activity-regulated expression of BDNF and cox-2 in a rat model.
    “... role in neuropathic pain by down-regulating p300/CBP HAT activity-mediated gene expression of BDNF...”
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  17. 12357
    Molecular recognition of the neurotransmitter acetylcholine by an acetylcholine binding protein reveals determinants of binding to nicotinic acetylcholine receptors.
    “... and Trp53 on the complementary side and a water-mediated hydrogen bond from acetylcholine to backbone...”
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  18. 12358
    Ubiquitination and degradation of ribonucleotide reductase M1 by the polycomb group proteins RNF2 and Bmi1 and cellular response to gemcitabine.
    “... ubiquitination sites. We show that ubiquitinated RRM1 undergoes proteasome-mediated degradation and that targeted...”
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  19. 12359
    Mouse primary microglia respond differently to LPS and poly(I:C) in vitro
    “... be associated with NF-κb and type I interferon pathways. Last, LPS- and poly(I:C)-activated microglia mediated...”
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  20. 12360
    Predicting GPAs with Executive Functioning Assessed by Teachers and by Adolescents Themselves
    “...Executive functions (EFs) show promise as important mediators of adolescent academic performance...”
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