Materias dentro de su búsqueda.
Mostrando 12,561 - 12,580 Resultados de 16,745 Para Buscar '"Mediator"', tiempo de consulta: 0.18s Limitar resultados
  1. 12561
    Inhibition of Bcl-2/Bcl-xL and c-MET causes synthetic lethality in model systems of glioblastoma
    “... decline in anti-apoptotic Mcl-1 levels. Silencing of Mcl-1 enhanced ABT263 and MET-inhibitor mediated...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  2. 12562
    IL-4 as a Repurposed Biological Drug for Myocardial Infarction through Augmentation of Reparative Cardiac Macrophages: Proof-of-Concept Data in Mice
    “... studies supported that these IL-4-mediated effects were induced via M2-like macrophages. On the other hand...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  3. 12563
    Characteristics of the heme catabolic pathway in mild unconjugated hyperbilirubinemia and their associations with inflammation and disease prevention
    “... inflammation, and are thus less prone to oxidative-stress mediated diseases....”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  4. 12564
    5T4-specific chimeric antigen receptor modification promotes the immune efficacy of cytokine-induced killer cells against nasopharyngeal carcinoma stem cell-like cells
    “... assays revealed that 5T4-28Z-CIK cells possessed both CAR-mediated and CAR-independent anti-NPC activity...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  5. 12565
    Phenome-wide association study for CYP2A6 alleles: rs113288603 is associated with hearing loss symptoms in elderly smokers
    “.... Cigarette smoking is associated with structural changes in the brain and CYP2A6 mediates these changes...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  6. 12566
    Chondroprotection by urocortin involves blockade of the mechanosensitive ion channel Piezo1
    “... that this channel inhibition by Ucn1 is mediated initially by an increase in cyclic adenosine monophosphate (cAMP...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  7. 12567
    Hyperosmolarity-induced AQP5 upregulation promotes inflammation and cell death via JNK1/2 Activation in human corneal epithelial cells
    “... in proinflammatory cytokine expression and cell death are mediated through AQP5 upregulation and JNK1/2 MAPK...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  8. 12568
    The CCR4-NOT complex contributes to repression of Major Histocompatibility Complex class II transcription
    “... and also in naïve macrophages from CNOT3 conditional knock-out mice. CNOT2-mediated repression of MHC II...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  9. 12569
    Relationship between somatic mosaicism of Pax6 mutation and variable developmental eye abnormalities—an analysis of CRISPR genome-edited mouse embryos
    “... targeted gene generated by CRISPR/Cas-mediated genome editing will give some insights for understanding...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  10. 12570
    MYD88 signals induce tumour-initiating cell generation through the NF-κB-HIF-1α activation cascade
    “... accumulation was not caused by enhanced protein stability but by NF-κB-mediated transcriptional activation...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  11. 12571
    Crystallographic texture and mineral concentration quantification of developing and mature human incisal enamel
    “...-mediated biomineralization events, but in particular because we can use our understanding of this natural...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  12. 12572
    Single vector platform vaccine protects against lethal respiratory challenge with Tier 1 select agents of anthrax, plague, and tularemia
    “...capB-vectored vaccines induces potent antigen-specific humoral and T-cell-mediated immune responses...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  13. 12573
    Improvement of Pharmacokinetic Profile of TRAIL via Trimer-Tag Enhances its Antitumor Activity in vivo
    “... target for cancer therapy because it mediates activation of the extrinsic apoptosis pathway in a tumor...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  14. 12574
    H2S and homocysteine control a novel feedback regulation of cystathionine beta synthase and cystathionine gamma lyase in cardiomyocytes
    “... SP1. In conclusion, we revealed a novel mechanism for H2S-mediated regulation of homocysteine...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  15. 12575
    A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C. elegans ALS model
    “...Abstract Small-conductance Ca2+-activated K+ (SK) channels mediate medium afterhyperpolarization...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  16. 12576
    Enhancing KCC2 function counteracts morphine-induced hyperalgesia
    “...) of the spinal cord, weakening spinal GABAA/glycine-mediated postsynaptic inhibition. Here, we tested whether...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  17. 12577
    Characterisation of a 3-hydroxypropionic acid-inducible system from Pseudomonas putida for orthogonal gene expression control in Escherichia coli and Cupriavidus necator
    “... in HpdR-mediated transcription activation. We investigate the kinetics and dynamics of the PpHpdR/P hpdH...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  18. 12578
    Toxoplasma gondii tachyzoite-extract acts as a potent immunomodulator against allergic sensitization and airway inflammation
    “..., offering new therapies for immune-mediated disorders....”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  19. 12579
    Defects and lithium migration in Li2CuO2
    “... as vehicles for the vacancy mediated lithium self-diffusion in Li2CuO2. It is shown that aluminium doping...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
  20. 12580
    Hsp90 inhibition as a means to inhibit activation of the NLRP3 inflammasome
    “... that facilitates the caspase-1-mediated maturation of IL-1β and IL-18. Inactive NLRP3 is guarded by a protein...”
    Enlace del recurso
    article
    Agregar a favoritos
    Guardado en:
Herramientas de búsqueda: RSS — Enviar por Correo electrónico esta Búsqueda — Guardar Búsqueda