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  1. 13141
    Sustained AMPK Activation and Proline Metabolism Play Critical Roles in the Survival of Matrix-Deprived Transformed Cells
    “...-dependent regulation of proline metabolism in mediating energy homeostasis and promoting survival of matrix...”
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  2. 13142
    TCP1 increases drug resistance in acute myeloid leukemia by suppressing autophagy via activating AKT/mTOR signaling
    “..., and TCP1-mediated autophagy inhibition conferred resistance to adriamycin-induced cell apoptosis...”
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  3. 13143
    Glycaemic variability in diabetes: a tool for assessing the quality of glycaemic control and the risk of complications
    “... that the effect of GV on vascular walls may be mediated by oxidative stress, chronic inflammation and endothelial...”
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  4. 13144
    Route of infectious bronchitis virus vaccination determines the type and magnitude of immune responses in table egg laying hens
    “... immune responses. Cell mediated immune gene transcripts (CD8-α and CD8-β) were up-regulated in turbinate...”
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  5. 13145
    USP12 promotes breast cancer angiogenesis by maintaining midkine stability
    “.... Overexpression of MDK rescued the loss of angiogenesis ability mediated by knockdown of USP12 in breast cancer...”
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  6. 13146
    Proteomic analysis of necroptotic extracellular vesicles
    “... during the early stage of necroptosis, mediated by the secretion of specific EVs that influences...”
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  7. 13147
    MRPS31 loss is a key driver of mitochondrial deregulation and hepatocellular carcinoma aggressiveness
    “... destruction, COL1A1 modulated invasiveness via the ZEB1-mediated epithelial-to-mesenchymal transition. Finally...”
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  8. 13148
    Cetuximab promotes RSL3-induced ferroptosis by suppressing the Nrf2/HO-1 signalling pathway in KRAS mutant colorectal cancer
    “... cetuximab-mediated regulation of p38/Nrf2/HO-1 promotes RSL3-induced ferroptosis and plays a pivotal role...”
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  9. 13149
    Epidemiology, mortality and effectiveness of prophylaxis for Pneumocystis jiroveci pneumonia among rheumatic patients: a territory-wide study
    “... (AAV), immune-mediated myositis (IMM), rheumatoid arthritis (RA), systemic lupus erythematosus (SLE...”
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  10. 13150
    Lipodystrophy at the insulin injection sites: current trends in epidemiology, diagnostics and prevention
    “... were described. As we moved to human insulin and insulin analogues, immune mediated atrophic form...”
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  11. 13151
    A rat model of severe VWD by elimination of the VWF gene using CRISPR/Cas9
    “... The entire VWF gene was eliminated in Sprague‐Dawley (Crl:SD) rats via CRISPR/Cas9‐mediated gene editing. VWF...”
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  12. 13152
    Downregulation of the Proton-Activated Cl- Channel TMEM206 Inhibits Malignant Properties of Human Osteosarcoma Cells
    por Fei Peng, Haohuan Li, Jianping Li, Zhe Wang
    Publicado 2021
    “... the β-catenin mediated downregulation of Wnt/β-catenin signaling. More importantly, TMEM206 knockdown...”
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  13. 13153
    Restorative potential of (−)-epicatechin in a rat model of Gulf War illness muscle atrophy and fatigue
    “... (Epi) to reverse skeletal muscle (SkM) atrophy and dysfunction, decrease mediators of inflammation...”
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  14. 13154
    Integration of transcriptomics and network analysis reveals co-expressed genes in Frankliniella occidentalis larval guts that respond to tomato spotted wilt virus infection
    por Jinlong Han, Dorith Rotenberg
    Publicado 2021
    “... of the developmentally-mediated interaction between thrips vectors and orthotospoviruses, and provide opportunities...”
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  15. 13155
    Silencing of UBE2D1 inhibited cell migration in gastric cancer, decreasing ubiquitination of SMAD4
    por Honghu Xie, Yu He, Yugang Wu, Qicheng Lu
    Publicado 2021
    “... biomarkers for early diagnosis and more effective therapy of GC. Methods In this study, lentivirus-mediated...”
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  16. 13156
    Melatonin enhances SIRT1 to ameliorate mitochondrial membrane damage by activating PDK1/Akt in granulosa cells of PCOS
    “... mediates mPTP to increase mitochondrial membrane potential. Furthermore, we found melatonin decreased...”
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  17. 13157
    NOX2β: A novel splice variant of NOX2 that regulates NADPH oxidase activity in macrophages.
    “..., selective siRNA-mediated knockdown of the transcript reduced expression of the 30 kDa protein in macrophages...”
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  18. 13158
    Genetic and environmental influences on the relationship between flow proneness, locus of control and behavioral inhibition.
    “.... We also found a mainly genetically mediated relationship between the three traits, suggesting...”
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  19. 13159
    Inactivation and inducible oncogenic mutation of p53 in gene targeted pigs.
    “... characteristic of cellular transformation. Cre mediated recombination activated the latent TP53(R167H) allele...”
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  20. 13160
    Alveolar macrophages play a key role in cockroach-induced allergic inflammation via TNF-α pathway.
    “... types in lung tissue, is known to mediate the cellular events caused by inhaled serine protease...”
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