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  1. 13601
    Endothelial-derived cardiovascular disease-related microRNAs elevated with prolonged sitting pattern among postmenopausal women
    “... in extracellular vesicles (EVs) reflect cell/tissue status and mediate intercellular communication. We explored...”
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  2. 13602
    Decoding empagliflozin’s molecular mechanism of action in heart failure with preserved ejection fraction using artificial intelligence
    “... of empagliflozin in HFpEF appeared to be predominantly mediated by inhibition of NHE1 (Na+/H+ exchanger 1...”
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  3. 13603
    Metabolomics analysis of the soapberry (Sapindus mukorossi Gaertn.) pericarp during fruit development and ripening based on UHPLC-HRMS
    “... of soapberry pericarp, as well as highlight the metabolites that could mediate the biological activity...”
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  4. 13604
    The LINC01119-SOCS5 axis as a critical theranostic in triple-negative breast cancer
    “... some have been described to play functional roles in TNBC, activities of lncRNAs as mediators of tumor...”
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  5. 13605
    Gestational exposure to chlordecone promotes transgenerational changes in the murine reproductive system of males
    “... binding sites, some of which we confirmed to be functional. Our data demonstrate that CD-mediated...”
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  6. 13606
    PmAP2-β depletion enhanced activation of the Toll signaling pathway during yellow head virus infection in the black tiger shrimp Penaeus monodon
    “.... Previous studies suggested that YHV enters shrimp cells via clathrin-mediated endocytosis. This research...”
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  7. 13607
    Virtual reality clinical-experimental tests of compassion treatment techniques to reduce paranoia
    “... controlled experimental design, with embedded tests for mediation. Study one targeted self-compassion via...”
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  8. 13608
    Health and safety at work
    por Eneida Sema, Ilda Melo
    Publicado 2012
    “... mapping methodology, articulated with the mediated learning experience, increase meaningful learning...”
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  9. 13609
    Promoter hypermethylation inactivates CDKN2A, CDKN2B and RASSF1A genes in sporadic parathyroid adenomas
    “... potential methylation-mediated inactivation of these genes in parathyroid adenomas. Gene expressions...”
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  10. 13610
    Human monocyte-derived type 1 and 2 macrophages recognize Ara h 1, a major peanut allergen, by different mechanisms
    “... interfering RNA knockdown of DC-SIGN did not suppress nAra h 1 uptake and nAra h 1-mediated cytokine...”
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  11. 13611
    Paracrine cyclooxygenase-2 activity by macrophages drives colorectal adenoma progression in the Apc Min/+ mouse model of intestinal tumorigenesis
    “... the hypothesis that paracrine Cox-2-mediated signalling from macrophages drives adenoma growth and progression...”
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  12. 13612
    Fenofibrate prevents iron induced activation of canonical Wnt/β-catenin and oxidative stress signaling in the retina
    “... of an iron chelator or an antioxidant reversed the iron-mediated upregulation of Wnt/β-catenin signaling...”
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  13. 13613
    Etv2 transcriptionally regulates Yes1 and promotes cell proliferation during embryogenesis
    “... that was expressed in Etv2-EYFP + cells at E7.75 and E8.25 using single cell RNA-seq analysis. Doxycycline-mediated...”
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  14. 13614
    Salvia fruticosa Induces Vasorelaxation In Rat Isolated Thoracic Aorta: Role of the PI3K/Akt/eNOS/NO/cGMP Signaling Pathway
    “... µM) significantly diminished SF-mediated vasorelaxation. Furthermore, SF induced Akt phosphorylation...”
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  15. 13615
    Naja sputatrix Venom Preconditioning Attenuates Neuroinflammation in a Rat Model of Surgical Brain Injury via PLA2/5-LOX/LTB4 Cascade Activation
    “... h and 72 h after SBI. The expression of pro-inflammatory mediators in peri-resection brain tissue...”
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  16. 13616
    Class II phosphatidylinositol 3-kinase-C2α is essential for Notch signaling by regulating the endocytosis of γ-secretase in endothelial cells
    “...-mediated endocytosis of γ-secretase complex, which allows for the cleavage of endocytosed Notch1 by γ...”
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  17. 13617
    Hepatocyte PRMT1 protects from alcohol induced liver injury by modulating oxidative stress responses
    “... induced a hepatocyte specific PRMT1 knockout using AAV mediated Cre delivery in mice fed either alcohol...”
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  18. 13618
    Smoking status and endothelial function in Japanese men
    “... status and endothelial function in detail in men. We measured flow-mediated vasodilation (FMD) in 2209...”
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  19. 13619
    Protection from α-Synuclein induced dopaminergic neurodegeneration by overexpression of the mitochondrial import receptor TOM20
    “... overexpression. The observed TOM20-mediated dopaminergic neuron preservation appeared to be due, in part...”
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  20. 13620
    Cathepsin S provokes interleukin-6 (IL-6) trans-signaling through cleavage of the IL-6 receptor in vitro
    “... of signaling. Regenerative and anti-inflammatory activities are mediated via classic signaling, in which IL-6...”
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