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  1. 14221
    The conserved residue Arg46 in the N-terminal heptad repeat domain of HIV-1 gp41 is critical for viral fusion and entry.
    “... infection and HIV-1-mediated cell-to-cell fusion. These results suggest that the positively charged residue...”
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  2. 14222
    The hepatic Raldh1 expression is elevated in Zucker fatty rats and its over-expression introduced the retinal-induced Srebp-1c expression in INS-1 cells.
    “.... The over-expression of RALDH1 introduced the retinal-mediated induction of Srebp-1c expression in INS-1...”
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  3. 14223
    Glutathione transferase from Trichoderma virens enhances cadmium tolerance without enhancing its accumulation in transgenic Nicotiana tabacum.
    “..., a biocontrol fungus and introducing it into Nicotiana tabacum plants by Agrobacterium-mediated gene...”
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  4. 14224
    Restoration of altered microRNA expression in the ischemic heart with resveratrol.
    “.... MicroRNAs are known regulators for genes involved in resveratrol-mediated cardiac remodeling...”
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  5. 14225
    The initial step in human immunodeficiency virus type 1 GagProPol processing can be regulated by reversible oxidation.
    “..., it is possible that the effects of oxidation on viral maturation are mediated in whole, or part, through effects...”
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  6. 14226
    Ligand-induced tyrosine phosphorylation of cysteinyl leukotriene receptor 1 triggers internalization and signaling in intestinal epithelial cells.
    “... arrestin-3, we suggest that a clathrin-, arrestin-3, and Rab-5-dependent process mediated...”
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  7. 14227
    Deletion of CDKAL1 affects mitochondrial ATP generation and first-phase insulin exocytosis.
    “... and the subsequent activity of Ca(2+) channels through pathways other than CDK5-mediated regulation....”
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  8. 14228
    PROINFLAMMATORY CYTOKINE LEVELS AND INDEXES OF ENDOTHELIAL FUNCTION IN PATIENTS WITH OSTEOARTHRITIS IS DEPENDENT ON THE PAIN INTENSITY
    por E. Yu. Aleksenko, S. M. Tsvinger
    Publicado 2017
    “.... Inflammatory mediators are able to induce activation and injury of endothelium causing its dysfunction. vWF...”
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  9. 14229
    CHEMOKINES AND THEIR RECEPTORS EXPRESSION IN BLOOD AND LIVER TISSUE IN CHRONIC HEPATITIS C
    “.... Chemokines and chemokine receptors are fascinating object for investigation since they are mediators...”
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  10. 14230
    Deguelin action involves c-Met and EGFR signaling pathways in triple negative breast cancer cells.
    “... analyses and immunostaining studies indicated that the deguelin effects may be mediated through EGFR-PAKT/c...”
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  11. 14231
    Comparative Genomics Reveal That Host-Innate Immune Responses Influence the Clinical Prevalence of Legionella pneumophila Serogroups.
    “... dissemination through resistance to the alternative pathway of complement mediated killing in the human host may...”
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  12. 14232
    Gα₁₂ drives invasion of oral squamous cell carcinoma through up-regulation of proinflammatory cytokines.
    “... of proinflammatory cytokines in their mediation of OSCC invasion. We found that both the transcription and protein...”
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  13. 14233
    Reciprocal regulation of NF-kB (Relish) and Subolesin in the tick vector, Ixodes scapularis.
    “... interacting proteins regulate the specificity of the NF-kB-mediated gene expression. These results suggested a...”
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  14. 14234
    Keratinocyte-targeted overexpression of the glucocorticoid receptor delays cutaneous wound healing.
    “... to contribute to the therapeutical effects mediated by GR; however their relative contribution to unwanted side...”
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  15. 14235
    Earthworm-mycorrhiza interactions can affect the diversity, structure and functioning of establishing model grassland communities.
    “... and AMF are important mediators of the diversity, structure and functioning of plant communities....”
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  16. 14236
    Interleukin-1 receptor-associated kinase-3 is a key inhibitor of inflammation in obesity and metabolic syndrome.
    “... inhibitor of IRAK/NFκB-mediated chronic inflammation, is downregulated in monocytes of obese persons. Low...”
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  17. 14237
    Platelets induce apoptosis during sepsis in a contact-dependent manner that is inhibited by GPIIb/IIIa blockade.
    “... than vehicle control mice.<h4>Conclusions</h4>In sepsis, platelet granzyme B-mediated apoptosis occurs...”
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  18. 14238
    The HCV non-nucleoside inhibitor Tegobuvir utilizes a novel mechanism of action to inhibit NS5B polymerase function.
    “...- mediated intracellular activation step and the resulting metabolite, after forming a glutathione conjugate...”
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  19. 14239
    Is the association between general cognitive ability and violent crime caused by family-level confounders?
    “... to be causal, potentially mediated through school adjustment problems and conduct disorder. Socioeconomic...”
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  20. 14240
    Characterization of pro-inflammatory flagellin proteins produced by Lactobacillus ruminis and related motile Lactobacilli.
    “... into the trait of flagellum-mediated motility in the lactobacilli....”
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