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  1. 14321
    Using Multiplexed CRISPR/Cas9 for Suppression of Cotton Leaf Curl Virus
    “... viral diseases. Here we demonstrate multiplex CRISPR/Cas-mediated genome editing against CLCuD using...”
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  2. 14322
    Heterologous Expression of the Melatonin-Related Gene <i>HIOMT</i> Improves Salt Tolerance in <i>Malus domestica</i>
    “...Melatonin, a widely known indoleamine molecule that mediates various animal and plant physiological...”
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  3. 14323
    TGFβ1 Secreted by Cancer-Associated Fibroblasts as an Inductor of Resistance to Photodynamic Therapy in Squamous Cell Carcinoma Cells
    “... to PDT of SCC13 cells was mediated by the elevated levels of TGFβ1 secreted by this cell line. Our...”
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  4. 14324
    Impact of Bicarbonate-β-Lactam Exposures on Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA) Gene Expression in Bicarbonate-β-Lactam-Responsive vs. Non-Responsive Strains
    “... models. Mechanistic studies to-date have implicated NaHCO<sub>3</sub>-mediated repression of genes...”
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  5. 14325
    High Glucose Reduces the Paracellular Permeability of the Submandibular Gland Epithelium via the MiR-22-3p/Sp1/Claudin Pathway
    “... permeability of SMG cells by inhibiting miR-22-3p/Sp1-mediated claudin-1 and claudin-3 expression....”
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  6. 14326
    Rapid, Cheap, and Effective COVID-19 Diagnostics for Africa
    “.... These include two isothermal nucleic acid amplification assays (loop-mediated isothermal amplification (LAMP...”
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  7. 14327
    Human Brown Adipose Tissue and Metabolic Health: Potential for Therapeutic Avenues
    “...-shivering thermogenesis mediated by mitochondrial uncoupling protein 1 (UCP1). Since the confirmation...”
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  8. 14328
    GM101 in Combination with Histone Deacetylase Inhibitor Enhances Anti-Tumor Effects in Desmoplastic Microenvironment
    “...- and clathrin-mediated endocytosis of Ad. The combination of GM101 with HDACi induced superior cancer cell...”
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  9. 14329
    Identification of Gene Co-Expression Networks Associated with Consensus Molecular Subtype-1 of Colorectal Cancer
    “..., microsatellite instability, chemokine-mediated signaling pathways, and immune responses. CMS1 also differentially...”
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  10. 14330
    Seagrass Patch Complexity Affects Macroinfaunal Community Structure in Intertidal Areas: An In Situ Experiment Using Seagrass Mimics
    “... and quantity) mediated by seagrass canopies were the main driving forces structuring this community...”
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  11. 14331
    Cyclin E1 in Murine and Human Liver Cancer: A Promising Target for Therapeutic Intervention during Tumour Progression
    “.... Additionally, the tumour microenvironment of <i>Ccne1</i>-deficient mice showed a reduction in immune mediators...”
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  12. 14332
    A hemolysin secretion pathway-based novel secretory expression platform for efficient manufacturing of tag peptides and anti-microbial peptides in Escherichia coli
    “... mediated the secretion but also decreased the toxicity of anti-microbial peptides (AMPs) to the host...”
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  13. 14333
    Effect of fermented Rhus verniciflua stokes extract on liver function parameters in healthy Korean adults: a double-blind randomized controlled trial
    “... lipidemic property mediated by the upregulation of AMP-activated protein kinase (AMPK) in cell and animal...”
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  14. 14334
    TLR2 and TLR4 in Parkinson’s disease pathogenesis: the environment takes a toll on the gut
    “... that toll-like receptors (TLRs), especially TLR2 and TLR4, are critical mediators of gut homeostasis...”
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  15. 14335
    Assemblage of indigenous arbuscular mycorrhizal fungi and green waste compost enhance drought stress tolerance in carob (Ceratonia siliqua L.) trees
    “... increased in C + AMF plants under DS. Overall, our findings suggest that the pairing of C + AMF can mediate...”
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  16. 14336
    Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation
    “...-mediated introduction of human ZNF212 into the Cb of 3-week-old Zfp212-KO mice prevented Purkinje cell...”
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  17. 14337
    Molecular differences of adipose-derived mesenchymal stem cells between non-responders and responders in treatment of  transphincteric perianal fistulas
    “... to be an effective and safe treatment for anal fistulas. AT mesenchymal stem cells (AT-MSCs) mediate the healing...”
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  18. 14338
    Efficacy of intranasal fluticasone propionate and budesonide in management of allergic rhinitis—a prospective comparative study
    “... mucosa induced by IgE-mediated hypersensitivity due to exposure of various allergens. AR occurs as a...”
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  19. 14339
    Effects of indulgent food snacking, with and without exercise training, on body weight, fat mass, and cardiometabolic risk markers in overweight and obese men
    “...‐mediated dilation (FMD) was not changed in any group. VO2max increased (p ≤ 0.001) in MICT (9.2%) and HIIT...”
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  20. 14340
    Phosphorylation of Lamin A/C at serine 22 modulates Nav1.5 function
    “... acid 22 substitution (S22D‐R545H‐LMNA). We found that S22A‐LMNA inhibited Lamin‐mediated activation...”
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