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  1. 14481
    The Mnn2 mannosyltransferase family modulates mannoprotein fibril length, immune recognition and virulence of Candida albicans.
    “... associated molecular patterns (PAMPs) recognised by the innate immune system. Glycan synthesis is mediated...”
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  2. 14482
    DNA break site at fragile subtelomeres determines probability and mechanism of antigenic variation in African trypanosomes.
    por Lucy Glover, Sam Alsford, David Horn
    Publicado 2013
    “.... We then induced high-efficiency meganuclease-mediated DSBs and monitored DSB-responses and DSB...”
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  3. 14483
    Extreme genetic fragility of the HIV-1 capsid.
    “... as a whole. The extreme genetic fragility of HIV-1 CA may be one reason why cell-mediated immune...”
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  4. 14484
    Neutralization serotyping of BK polyomavirus infection in kidney transplant recipients.
    “... on antibody-mediated neutralization of BKV genotype I and IV reporter vectors (pseudoviruses). Neutralization...”
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  5. 14485
    The Plasmodium berghei Ca(2+)/H(+) exchanger, PbCAX, is essential for tolerance to environmental Ca(2+) during sexual development.
    “... the ionic microenvironment of the mosquito midgut. Ca(2+) homeostasis mediated by PbCAX is critical...”
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  6. 14486
    Negative regulation of type I IFN expression by OASL1 permits chronic viral infection and CD8⁺ T-cell exhaustion.
    “... on IFN-I receptor signaling. Together, these results demonstrate that OASL1-mediated negative regulation...”
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  7. 14487
    Calcium influx rescues adenylate cyclase-hemolysin from rapid cell membrane removal and enables phagocyte permeabilization by toxin pores.
    “...774A.1 macrophages at concentrations starting from 100 ng/ml. Hence, by mediating calcium influx...”
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  8. 14488
    Nitric oxide synthase dysfunction contributes to impaired cerebroarteriolar reactivity in experimental cerebral malaria.
    “... in the brain during ECM development strongly indicate a state of eNOS/nNOS uncoupling likely mediated...”
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  9. 14489
    The RBP-Jκ binding sites within the RTA promoter regulate KSHV latent infection and cell proliferation.
    “..., the development of KSHV-mediated lymphoproliferative disease is not fully understood. Here, we generated two...”
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  10. 14490
    Structure and assembly of a trans-periplasmic channel for type IV pili in Neisseria meningitidis.
    “... is mediated by a specialized secretin protein, PilQ, but the way in which this large channel is formed...”
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  11. 14491
    The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
    “... of phosphotyrosine-mediated signaling in a broad range of cellular functions and virulence....”
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  12. 14492
    Critical and independent role for SOCS3 in either myeloid or T cells in resistance to Mycobacterium tuberculosis.
    “... in infected macrophages and DCs prevented the IL-6-mediated inhibition of TNF and IL-12 secretion...”
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  13. 14493
    Structural basis for the ABO blood-group dependence of Plasmodium falciparum rosetting.
    “... of infected red blood cells (iRBCs) with uninfected RBCs. Rosetting is mediated by a subgroup of PfEMP1...”
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  14. 14494
    Novel immunomodulators from hard ticks selectively reprogramme human dendritic cell responses.
    “... the greatest diversity of pathogens of any arthropod vector. Tick-induced immunomodulation is mediated...”
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  15. 14495
    The anti-repressor MecR2 promotes the proteolysis of the mecA repressor and enables optimal expression of β-lactam resistance in MRSA.
    “..., presumably mediated by native cytoplasmatic proteases. These observations point to a revision of the current...”
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  16. 14496
    Functional cure of SIVagm infection in rhesus macaques results in complete recovery of CD4+ T cells and is reverted by CD8+ cell depletion.
    “... be at least in part immune mediated. Viral control was independent of MHC, partial APOBEC restriction...”
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  17. 14497
    Wnt/β-catenin signaling induces the aging of mesenchymal stem cells through the DNA damage response and the p53/p21 pathway.
    por Da-yong Zhang, Hai-jie Wang, Yu-zhen Tan
    Publicado 2011
    “... and p53/p21 pathway may be the main mediators of MSC aging induced by excessive activation of Wnt/β...”
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  18. 14498
    hHGF overexpression in myoblast sheets enhances their angiogenic potential in rat chronic heart failure.
    “... from histological sections at 4 weeks. Paracrine mediators from L6-HGF myoblast sheets effectively...”
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  19. 14499
    The adaptor function of TRAPPC2 in mammalian TRAPPs explains TRAPPC2-associated SEDT and TRAPPC9-associated congenital intellectual disability.
    “..., mediating the formation of TRAPPII and/or TRAPPIII. Furthermore, disease-causing deletional mutants...”
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  20. 14500
    Predator diversity and abundance provide little support for the enemies hypothesis in forests of high tree diversity.
    “... roles in mediating the observed relationships between spider and plant diversity, but further testing...”
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