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  1. 15061
    Identification of Piwil2-like (PL2L) proteins that promote tumorigenesis.
    “... and might mediate a common pathway for tumor development without tissue restriction. The identification...”
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  2. 15062
    Genetic variation in the TNF gene is associated with susceptibility to severe sepsis, but not with mortality.
    “...<h4>Background</h4>Tumor necrosis factor (TNF) and TNF receptor superfamily (TNFR)-mediated immune...”
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  3. 15063
    Lack or inhibition of dopaminergic stimulation induces a development increase of striatal tyrosine hydroxylase-positive interneurons.
    “... regulates the number of striatal TH(+) neurons by direct and indirect mechanisms mediated by multiple DA...”
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  4. 15064
    Puerarin suppresses proliferation of endometriotic stromal cells partly via the MAPK signaling pathway induced by 17ß-estradiol-BSA.
    “...-mediated activation of ERK1/2 in ESCs and this phenomenon was associated with an increased proliferation...”
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  5. 15065
    The effects of vitamin D receptor silencing on the expression of LVSCC-A1C and LVSCC-A1D and the release of NGF in cortical neurons.
    “... protein in cortical neurons. These results suggest a potential role for vitamin D and vitamin D-mediated...”
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  6. 15066
    O-methylguanine-DNA methyltransferase (MGMT) mRNA expression predicts outcome in malignant glioma independent of MGMT promoter methylation.
    “... expression.<h4>Conclusions/significance</h4>MGMT mRNA expression plays a direct role for mediating tumor...”
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  7. 15067
    IL-1β stimulates COX-2 dependent PGE₂ synthesis and CGRP release in rat trigeminal ganglia cells.
    “..., which reduce CGRP release, and cyclooxygenase (COX) inhibitors can abort trigeminally mediated pain...”
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  8. 15068
    Synphilin-1 enhances α-synuclein aggregation in yeast and contributes to cellular stress and cell death in a Sir2-dependent manner.
    “... induces cytotoxicity, an effect most pronounced for the wild-type protein and mediated via Sir2-dependent...”
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  9. 15069
    ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends of ZNF genes.
    “... histone methyltransferases (e.g. G9a and SETDB1) may be involved in mediating the H3K9me3 silencing mark...”
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  10. 15070
    Defects in innate immunity render breast cancer initiating cells permissive to oncolytic adenovirus.
    “... induced type I interferon (IFN) response regulation in these cell types. We show TLR mediated virus...”
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  11. 15071
    STK35L1 associates with nuclear actin and regulates cell cycle and migration of endothelial cells.
    “... domains motif was identified in STK35L1 that mediated its interaction with actin. Depletion of STK35L1...”
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  12. 15072
    CULTURES OF FIBROBLAST-LIKE SYNOVIAL CELLS FROM PATIENTS WITH RHEUMATOID ARTHRITIS: PROPERTIES AND OPPORTUNITIES
    “... to be hypermethylated. An increased histone acetylation of genes encoding proinflammatory mediators (such as MMP1) may...”
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  13. 15073
    Influence of 17β-estradiol on gene expression of Paracoccidioides during mycelia-to-yeast transition.
    “... protein showed high expression. Genes related to ubiquitin-mediated protein degradation, and oxidative...”
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  14. 15074
    Fusion to snowdrop lectin magnifies the oral activity of insecticidal ω-Hexatoxin-Hv1a peptide by enabling its delivery to the central nervous system.
    “... associated with the central nerve chord.<h4>Conclusions/significance</h4>In addition to mediating transport...”
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  15. 15075
    Augmented TLR2 expression on monocytes in both human Kawasaki disease and a mouse model of coronary arteritis.
    “... of coronary arteritis in human KD by modulating TLR2-mediated immune activation on CD14+ monocytes....”
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  16. 15076
    The role of the multiple banded antigen of Ureaplasma parvum in intra-amniotic infection: major virulence factor or decoy?
    “... finding. This host response may be important in the pathogenesis of inflammation-mediated adverse...”
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  17. 15077
    Additive contributions of two manganese-cored superoxide dismutases (MnSODs) to antioxidation, UV tolerance and virulence of Beauveria bassiana.
    “...-contribute to the biocontrol potential of B. bassiana by mediating cellular antioxidative response....”
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  18. 15078
    Analysis of miRNA and mRNA expression profiles highlights alterations in ionizing radiation response of human lymphocytes under modeled microgravity.
    “... pathway can originate from alteration in the functionality of the microRNA-mediated gene regulation, being...”
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  19. 15079
    Hepatitis B vaccine antibody response and the risk of clinical AIDS or death.
    “... hypersensitivity skin test responses (an in vivo marker of cell-mediated immunity). This association remained...”
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  20. 15080
    The scaffolding protein Dlg1 is a negative regulator of cell-free virus infectivity but not of cell-to-cell HIV-1 transmission in T cells.
    “...) is predominantly mediated by cellular structures such as the virological synapse (VS). The VS formed between an HIV...”
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