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  1. 15101
    Activation of a Ductal-to-Endocrine Transdifferentiation Transcriptional Program in the Pancreatic Cancer Cell Line PANC-1 Is Controlled by RAC1 and RAC1b through Antagonistic Regulation of Stemness Factors
    “.... Finally, rescue experiments involving pharmacological or RNA interference-mediated inhibition of RAC1...”
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  2. 15102
    Elucidating the role of free polycationic chains in polycation gene carriers by free chains of polyethylenimine or N,N,N-trimethyl chitosan plus a certain polyplex
    por Xu T, Lui W, Wang SH, Shao ZZ
    Publicado 2014
    “..., by shutting down the clathrin-mediated endocytosis or vacuolar proton pump, the transfection efficiency...”
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  3. 15103
    Transferrin receptor-targeted pH-sensitive micellar system for diminution of drug resistance and targetable delivery in multidrug-resistant breast cancer
    por Gao W, Ye G, Duan X, Yang X, Yang VC
    Publicado 2017
    “... to the synergistic effect of poly(l-histidine)-triggered endolysosom escape and TfR-mediated endocytosis. Most...”
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  4. 15104
    Psychological well-being in individuals with mild cognitive impairment
    “... reduced model, then hierarchical regression with the Baron Kenny test of mediation derived the final three...”
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  5. 15105
    Aggregation is a critical cause of poor transfer into the brain tissue of intravenously administered cationic PAMAM dendrimer nanoparticles
    “...-mediated endocytosis, but not by an inhibitor of macropinocytosis. Physicochemical analysis of the PD...”
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  6. 15106
    Liposome-based polymer complex as a novel adjuvant: enhancement of specific antibody production and isotype switch
    “... appropriate immunity against pathogens. Antibody-mediated immunity is critical for protection against many...”
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  7. 15107
    A reinforced composite structure composed of polydiacetylene assemblies deposited on polystyrene microspheres and its application to H5N1 virus detection
    por Dong WJ, Luo J, He HX, Jiang L
    Publicado 2013
    “... be mediated by changing the extent of layer deposition, which affected the sensitivity of detection. It showed...”
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  8. 15108
    Immunoliposome co-delivery of bufalin and anti-CD40 antibody adjuvant induces synergetic therapeutic efficacy against melanoma
    por Li Y, Yuan J, Yang Q, Cao W, Zhou X, Xie Y, Tu H, Zhang Y, Wang S
    Publicado 2014
    “... transferase-mediated dUTP-Fluorescein nick end labeling and Western blot assay. Meanwhile, anti-CD40-BFL...”
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  9. 15109
    Evaluation of highly carbonated hydroxyapatite bioceramic implant coatings with hierarchical micro-/nanorod topography optimized for osseointegration
    por Li S, Yu W, Zhang W, Zhang G, Yu L, Lu E
    Publicado 2018
    “... surface bioactivity and biocompatibility, as well as better wettability, which mediated improved protein...”
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  10. 15110
    Effects of Wharton's jelly-derived mesenchymal stem cells on neonatal neutrophils
    “... of inflammatory, oxidant, and antioxidant mediators in adult and neonatal neutrophils.Methods: WJ-MSCs were...”
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  11. 15111
    Targeted tumor imaging of anti-CD20-polymeric nanoparticles developed for the diagnosis of B-cell malignancies
    “.... NPs’ binding specificity mediated by anti-CD20 antibody was evaluated on MEC1 cells and chronic...”
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  12. 15112
    Size-dependent cytotoxicity of Fe3O4 nanoparticles induced by biphasic regulation of oxidative stress in different human hepatoma cells
    por Xie Y, Liu D, Cai C, Chen X, Zhou Y, Wu L, Sun Y, Dai H, Kong X, Liu P
    Publicado 2016
    “... and by inducing necrosis mediated through the mitochondria-dependent intracellular reactive oxygen species...”
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  13. 15113
    Parallel comparative studies on toxicity of quantum dots synthesized and surface engineered with different methods in vitro and in vivo
    por Liu F, Ye W, Wang J, Song F, Cheng Y, Zhang B
    Publicado 2017
    “... surface engineered by glutathione-mediated ligand exchange (denoted as QDs-2), and the ones prepared...”
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  14. 15114
    Slowly Progressive Type 1 Diabetes Mellitus: Current Knowledge And Future Perspectives
    “...-mediated insulitis, a marker of type 1 diabetes; pseudoatrophic islets (islets specifically devoid of beta...”
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  15. 15115
    Clinical potential of sodium-glucose cotransporter 2 inhibitors in the management of type 2 diabetes
    por Kim Y, Babu AR
    Publicado 2012
    “... (SGLT2) mediates most of the glucose reabsorption from the proximal renal tubule. Inhibition of SGLT2...”
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  16. 15116
    Rho GTPases in A549 and Caco-2 cells dominating the endocytic pathways of nanocarbons with different morphologies
    “..., the cellular uptake of oxMWCNT was clathrin-mediated and oxGRAPHENE was caveolin-modulated, both...”
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  17. 15117
    Cellular uptake mechanism and comparative evaluation of antineoplastic effects of paclitaxel–cholesterol lipid emulsion on triple-negative and non-triple-negative breast cancer cell lines
    “...-mediated internalization pathway via clathrin-coated pits, localized in lysosomes, and then released...”
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  18. 15118
    Small interfering RNAs (siRNAs) in cancer therapy: a nano-based approach
    “... discuss the progress of siRNA therapy as well as its medical application via nanoparticle-mediated...”
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  19. 15119
    CPX-351: a nanoscale liposomal co-formulation of daunorubicin and cytarabine with unique biodistribution and tumor cell uptake properties
    por Mayer LD, Tardi P, Louie AC
    Publicado 2019
    “... bypassing P-glycoprotein-based efflux pumps, which are important mediators of chemotherapy resistance...”
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  20. 15120
    Structural and functional comparability study of anti-CD20 monoclonal antibody with reference product
    “... are being used to treat B-cell malignancies and B-cell mediated autoimmune diseases. Considering the cost...”
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