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  1. 16081
    αvβ3 integrin-targeted micellar mertansine prodrug effectively inhibits triple-negative breast cancer in vivo
    por Zhong P, Gu X, Cheng R, Deng C, Meng F, Zhong Z
    Publicado 2017
    “... demonstrated that cRGD-MMP mediated a clearly more efficient cellular uptake and intracellular release...”
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  2. 16082
    A Potent and Safer Anticancer and Antibacterial Taxus-Based Green Synthesized Silver Nanoparticle
    por Sarli S, Kalani MR, Moradi A
    Publicado 2020
    “... bacteria, respectively).Conclusion: The production of herbal-mediated silver nanoparticles may...”
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  3. 16083
    Yu Nu Compound Regulates Autophagy and Apoptosis Through mTOR in vivo and vitro
    por He C, Liu G, Zhuang S, Zhang J, Chen Y, Li H, Huang Z, Zheng Y
    Publicado 2020
    “... to treat type 2 diabetes possibly through mediating autophagy. Abnormal podocyte autophagy and apoptosis...”
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  4. 16084
    Ulva lactuca polysaccharides prevent Wistar rat breast carcinogenesis through the augmentation of apoptosis, enhancement of antioxidant defense system, and suppression of inflammation
    “.... These preventive effects may be mediated through the augmentation of apoptosis, suppression of oxidative stress...”
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  5. 16085
    Factors correlated with the improvement of endothelial dysfunction during Abatacept therapy in patients with rheumatoid arthritis
    “... flow-mediated dilation (FMD) of 45 rheumatoid arthritis patients without known cardiovascular risk...”
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  6. 16086
    Lack of change in glucose metabolism in eszopiclone-treated primary insomnia patients
    “...-mediated glucose uptake.Conclusion: Treatment with 3 mg eszopiclone for 2 months, compared with placebo...”
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  7. 16087
    Enhanced endosomal escape by photothermal activation for improved small interfering RNA delivery and antitumor effect
    por Yang X, Fan B, Gao W, Li L, Li T, Sun J, Peng X, Li X, Wang Z, Wang B, Zhang R, Xie J
    Publicado 2018
    “...: These findings suggest that the M-PLL-mediated siRNA delivery is a promising candidate for therapeutic siRNA...”
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  8. 16088
    Development of PLGA-lipid nanoparticles with covalently conjugated indocyanine green as a versatile nanoplatform for tumor-targeted imaging and drug delivery
    por Xin Y, Liu T, Yang CL
    Publicado 2016
    “... via FA receptor-mediated endocytosis. Furthermore, FA-RIPNPs (containing 50 µg/mL RSV...”
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  9. 16089
    Study on the prostate cancer-targeting mechanism of aptamer-modified nanoparticles and their potential anticancer effect in vivo
    “... *These authors contributed equally to this work Abstract: Ligand-mediated prostate cancer (PCa)-targeting...”
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  10. 16090
    Efficacy and mechanism of tanshinone IIA liquid nanoparticles in preventing experimental postoperative peritoneal adhesions in vivo and in vitro
    por Qin F, Ma Y, Li X, Wang X, Wei Y, Hou C, Lin S, Hou L, Wang C
    Publicado 2015
    “... studies showed that these effects may be mediated by the TGF-β signal pathway. Keywords: peritoneal...”
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  11. 16091
    Single peptide ligand-functionalized uniform hollow mesoporous silica nanoparticles achieving dual-targeting drug delivery to tumor cells and angiogenic blood vessel cells
    por Liu Y, Chen Q, Xu M, Guan G, Hu W, Liang Y, Zhao X, Qiao M, Chen D, Liu H
    Publicado 2015
    “...-mediated endocytosis pathway has a primary role in the transport of tHMSN into the cytoplasm.Conclusion...”
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  12. 16092
    Identification of Pharmacological Autophagy Regulators of Active Ulcerative Colitis
    “... of UC, and the therapeutic effect of some UC drugs is mediated by regulating autophagy pathways...”
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  13. 16093
    Biomarkers of subclinical atherosclerosis in patients with psoriatic arthritis
    “..., Ferrara, ItalyBackground: Psoriatic arthritis (PsA) is a chronic immune-mediated disease. It is associated...”
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  14. 16094
    Renal-targeted delivery of triptolide by entrapment in pegylated TRX-20-modified liposomes
    por Yuan Z, Jia L, Lim LY, Lin J, Shu G, Zhao L, Ye G, Liang X, Ji H, Fu H
    Publicado 2017
    “...) in an attempt to prolong their circulation in blood and enhance TP-mediated immune suppression. Due to specific...”
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  15. 16095
    Marine pollutant exposures and human milk extracellular vesicle-microRNAs in a mother-infant cohort from the Faroe Islands
    “... biologically relevant cargo from mother to infant, including microRNAs (miRNAs), and may partly mediate...”
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  16. 16096
    A Functional Human-on-a-Chip Autoimmune Disease Model of Myasthenia Gravis for Development of Therapeutics
    “... between pathological mechanisms of antibody-mediated receptor disruption including blocking, receptor...”
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  17. 16097
    PLASMINOGEN ACTIVATOR OF YERSINIA PESTIS
    “.... Pla-mediated ability of Y. pestis for selective binding with extracellular matrix and basal membranes...”
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  18. 16098
    Prostaglandin E2 sensitizes the cough reflex centrally via EP3 receptor-dependent activation of NaV 1.8 channels
    “... understood. Inflammatory mediators, such as prostaglandin E2 (PGE2), have been implicated in both peripheral...”
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  19. 16099
    CONCEPÇÕES E POTENCIALIDADES DO MEMORIAL MINAS GERAIS VALE PARA O ENSINO DE HISTÓRIA (Dossíê: As Dinâmicas do Patrimônio Cultural da Materialidade a Imaterialidade)
    “... mediated visit to the Africanities axis of the Minas Gerais Vale Memorial. The dialogues in the classroom...”
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  20. 16100
    Gasdermin D deficiency attenuates arthritis induced by traumatic injury but not autoantibody-assembled immune complexes
    “... fragments form plasma membrane pores, which mediate the secretion of IL-1β and IL-18 and cause...”
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