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  1. 16361
    A Simple and Universal System for Gene Manipulation in <named-content content-type="genus-species">Aspergillus fumigatus</named-content>: <italic toggle="yes">In Vitro</italic>-Assembled Cas9-Guide RNA Ribonucleoproteins Coupled with Microhomology Repair Templates
    “... system utilizes 35 to 50 bp of flanking regions for mediating homologous recombination at Cas9 double...”
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  2. 16362
    Gene Knockout Shows That PML (TRIM19) Does Not Restrict the Early Stages of HIV-1 Infection in Human Cell Lines
    “...)-mediated inhibition of HIV-1 in MEFs. Additionally, PML caused transcriptional repression of the HIV-1...”
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  3. 16363
    The Endoplasmic Reticulum-Mitochondrion Tether ERMES Orchestrates Fungal Immune Evasion, Illuminating Inflammasome Responses to Hyphal Signals
    “... mitochondrial regulator that lacks human homologs. We show that ERMES mediates Candida escape via inflammasome...”
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  4. 16364
    Environmentally Endemic <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content> Strains with Mutations in <italic toggle="yes">lasR</italic> Are Associated with Increased Disease Severity in Corneal Ulcers
    “... the role for LasR-mediated regulation of virulence is more complex than previously appreciated....”
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  5. 16365
    A Small <italic toggle="yes">Wolbachia</italic> Protein Directly Represses Phage Lytic Cycle Genes in “<italic toggle="yes">Candidatus</italic> Liberibacter asiaticus” within Psyllids
    “... in “Ca. Liberibacter asiaticus” may be critical to survival of both endosymbionts, since phage-mediated...”
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  6. 16366
    Impact of Engineered Expression of Mitochondrial Association Factor 1b on <italic toggle="yes">Toxoplasma gondii</italic> Infection and the Host Response in a Mouse Model
    por Elizabeth D. English, Jon P. Boyle
    Publicado 2018
    “... membrane. This phenotype is T. gondii strain specific and is mediated by expression of a host mitochondrial...”
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  7. 16367
    <italic toggle="yes">Pseudomonas aeruginosa</italic> Protease IV Exacerbates Pneumococcal Pneumonia and Systemic Disease
    “... in vivo. Moreover, PIV-mediated enhancement of pneumonia and disease severity was dependent...”
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  8. 16368
    Recovirus NS1-2 Has Viroporin Activity That Induces Aberrant Cellular Calcium Signaling To Facilitate Virus Replication
    “...-mediated calcium signaling may be a broadly utilized pathway for enteric virus replication, and its...”
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  9. 16369
    Contribution of Cytidine Deaminase to Thymidylate Biosynthesis in <named-content content-type="genus-species">Trypanosoma brucei</named-content>: Intracellular Localization and Properties of the Enzyme
    “... with previous studies, we show that RNA interference (RNAi)-mediated CDA depletion impairs T. brucei...”
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  10. 16370
    <named-content content-type="genus-species">Trypanosoma brucei</named-content> Pex13.2 Is an Accessory Peroxin That Functions in the Import of Peroxisome Targeting Sequence Type 2 Proteins and Localizes to Subdomains of the Glycosome
    “.../peroxisome biogenesis is mediated by proteins called peroxins that facilitate organelle formation...”
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  11. 16371
    <named-content content-type="genus-species">Candida glabrata</named-content> Has No Enhancing Role in the Pathogenesis of <italic toggle="yes">Candida</italic>-Associated Denture Stomatitis in a Rat Model
    “... modulation of C. albicans-mediated pathogenic effects. These data suggest that C. glabrata readily...”
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  12. 16372
    Phosphorylation of FtsZ and FtsA by a DNA Damage-Responsive Ser/Thr Protein Kinase Affects Their Functional Interactions in <italic toggle="yes">Deinococcus radiodurans</italic>
    “.... Here we report RqkA-mediated phosphorylation of cell division proteins FtsZ and FtsA in vitro...”
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  13. 16373
    Circulating Neutrophil-Derived Microparticles Associated with the Prognosis of Patients with Sepsis
    por Chen HP, Wang XY, Pan XY, Hu WW, Cai ST, Joshi K, Deng LH, Ma D
    Publicado 2020
    “... in pro-inflammatory mediators and sepsis severity score (p &lt; 0.05) as well as mortality.Conclusion...”
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  14. 16374
    Tuftsin-Bearing Liposomes Co-Encapsulated with Doxorubicin and Curcumin Efficiently Inhibit EAC Tumor Growth in Mice
    “... blot analysis revealed that the tumor inhibition was associated with p53-mediated apoptotic pathway...”
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  15. 16375
    Moderating Effect of BMI on the Relationship Between Sympathetic Activation and Blood Pressure in Males with Obstructive Sleep Apnea
    por Chen B, Somers VK, Tang X, Li Y
    Publicado 2021
    “... activation is a primary mechanism mediating increased blood pressure (BP) in obstructive sleep apnea (OSA...”
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  16. 16376
    Photothermal effects of NaYF4:Yb,Er@PE3@Fe3O4 superparamagnetic nanoprobes in the treatment of melanoma
    por Wang X, Kang C, Pan Y, Jiang R
    Publicado 2019
    “... tumor xenografts. Mechanistic studies suggested an involvement of heat shock protein 70 in mediating...”
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  17. 16377
    Endothelial Function in Obese Patients Treated with Bariatric Surgery
    “... by flow-mediated dilation (FMD) of the brachial artery. Also, carotid intima-media thickness (c-IMT...”
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  18. 16378
    Design of pH-sensitive methotrexate prodrug-targeted curcumin nanoparticles for efficient dual-drug delivery and combination cancer therapy
    por Xie JJ, Fan ZX, Li Y, Zhang YY, Yu F, Su GH, Xie LY, Hou ZQ
    Publicado 2018
    “... into the cancer cells via folate receptor-mediated endocytosis followed by the rapid intracellular release of CUR...”
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  19. 16379
    Emerging treatments in lung cancer &ndash; targeting the RLIP76 molecular transporter
    por Goldfinger LE, Lee S
    Publicado 2013
    “... is often the result of efflux of the drugs from cancer cells, mediated by adenosine triphosphate (ATP...”
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  20. 16380
    Icariin-loaded porous scaffolds for bone regeneration through the regulation of the coupling process of osteogenesis and osteoclastic activity
    por Xie Y, Sun W, Yan F, Liu H, Deng Z, Cai L
    Publicado 2019
    “... scaffolds to load icariin and promote bone regeneration in situ through mediation of the coupling processes...”
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