Contact-independent killing mediated by a T6SS effector with intrinsic cell-entry properties

por Li Song, Junfeng Pan, Yantao Yang, Zhenxing Zhang, Rui Cui, Shuangkai Jia, Zhuo Wang, Changxing Yang, Lei Xu, Tao G. Dong, Yao Wang, Xihui Shen
Publicado 2021

Extracellular-matrix-mediated osmotic pressure drives Vibrio cholerae biofilm expansion and cheater exclusion

por Jing Yan, Carey D. Nadell, Howard A. Stone, Ned S. Wingreen, Bonnie L. Bassler
Publicado 2017

Antagonizing the spindle assembly checkpoint silencing enhances paclitaxel and Navitoclax-mediated apoptosis with distinct mechanistic

por Ana C. Henriques, Patrícia M. A. Silva, Bruno Sarmento, Hassan Bousbaa
Publicado 2021

BNIP3L/NIX-mediated mitophagy protects against glucocorticoid-induced synapse defects

por Gee Euhn Choi, Hyun Jik Lee, Chang Woo Chae, Ji Hyeon Cho, Young Hyun Jung, Jun Sung Kim, Seo Yihl Kim, Jae Ryong Lim, Ho Jae Han
Publicado 2021

Disrupting the LINC complex by AAV mediated gene transduction prevents progression of Lamin induced cardiomyopathy

por Ruth Jinfen Chai, Hendrikje Werner, Peter Yiqing Li, Yin Loon Lee, Khaing Thet Nyein, Irina Solovei, Tuan Danh Anh Luu, Bhavya Sharma, Raju Navasankari, Martina Maric, Lois Yu En Sim, Ying Jie Loh, Edita Aliwarga, Jason Wen Long Cheong, Alexandre Chojnowski, Matias Ilmari Autio, Yu Haiyang, Kenneth Kian Boon Tan, Choong Tat Keng, Shi Ling Ng, Wei Leong Chew, Michael Ferenczi, Brian Burke, Roger Sik Yin Foo, Colin L. Stewart
Publicado 2021

Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation

por Zhe Ji, Lizhi He, Asaf Rotem, Andreas Janzer, Christine S. Cheng, Aviv Regev, Kevin Struhl
Publicado 2018

CRISPR/Cas9-mediated targeted mutagenesis in Japanese cedar (Cryptomeria japonica D. Don)

por Yoshihiko Nanasato, Masafumi Mikami, Norihiro Futamura, Masaki Endo, Mitsuru Nishiguchi, Yasunori Ohmiya, Ken-ichi Konagaya, Toru Taniguchi
Publicado 2021

MDM2 E3 ligase-mediated ubiquitination and degradation of HDAC1 in vascular calcification

por Duk-Hwa Kwon, Gwang Hyeon Eom, Jeong Hyeon Ko, Sera Shin, Hosouk Joung, Nakwon Choe, Yoon Seok Nam, Hyun-Ki Min, Taewon Kook, Somy Yoon, Wanseok Kang, Yong Sook Kim, Hyung Seok Kim, Hyuck Choi, Jeong-Tae Koh, Nacksung Kim, Youngkeun Ahn, Hyun-Jai Cho, In-Kyu Lee, Dong Ho Park, Kyoungho Suk, Sang Beom Seo, Erin R. Wissing, Susan M. Mendrysa, Kwang-Il Nam, Hyun Kook
Publicado 2016

L-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast

por Lena Hochrein, Leslie A. Mitchell, Karina Schulz, Katrin Messerschmidt, Bernd Mueller-Roeber
Publicado 2018

Intracellular interleukin-32γ mediates antiviral activity of cytokines against hepatitis B virus

por Doo Hyun Kim, Eun-Sook Park, Ah Ram Lee, Soree Park, Yong Kwang Park, Sung Hyun Ahn, Hong Seok Kang, Ju Hee Won, Yea Na Ha, ByeongJune Jae, Dong-Sik Kim, Woo-Chang Chung, Moon Jung Song, Kee-Hwan Kim, Seung Hwa Park, Soo-Hyun Kim, Kyun-Hwan Kim
Publicado 2018

Virtual memory T cells develop and mediate bystander protective immunity in an IL-15-dependent manner

por Jason T. White, Eric W. Cross, Matthew A. Burchill, Thomas Danhorn, Martin D. McCarter, Hugo R. Rosen, Brian O’Connor, Ross M. Kedl
Publicado 2016

NIR-II bioluminescence for in vivo high contrast imaging and in situ ATP-mediated metastases tracing

por Lingfei Lu, Benhao Li, Suwan Ding, Yong Fan, Shangfeng Wang, Caixia Sun, Mengyao Zhao, Chun-Xia Zhao, Fan Zhang
Publicado 2020

Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

por Linda Kachuri, Mattias Johansson, Sara R. Rashkin, Rebecca E. Graff, Yohan Bossé, Venkata Manem, Neil E. Caporaso, Maria Teresa Landi, David C. Christiani, Paolo Vineis, Geoffrey Liu, Ghislaine Scelo, David Zaridze, Sanjay S. Shete, Demetrius Albanes, Melinda C. Aldrich, Adonina Tardón, Gad Rennert, Chu Chen, Gary E. Goodman, Jennifer A. Doherty, Heike Bickeböller, John K. Field, Michael P. Davies, M. Dawn Teare, Lambertus A. Kiemeney, Stig E. Bojesen, Aage Haugen, Shanbeh Zienolddiny, Stephen Lam, Loïc Le Marchand, Iona Cheng, Matthew B. Schabath, Eric J. Duell, Angeline S. Andrew, Jonas Manjer, Philip Lazarus, Susanne Arnold, James D. McKay, Nima C. Emami, Matthew T. Warkentin, Yonathan Brhane, Ma’en Obeidat, Richard M. Martin, Caroline Relton, George Davey Smith, Philip C. Haycock, Christopher I. Amos, Paul Brennan, John S. Witte, Rayjean J. Hung
Publicado 2020

Evolutionary selection of biofilm-mediated extended phenotypes in Yersinia pestis in response to a fluctuating environment

por Yujun Cui, Boris V. Schmid, Hanli Cao, Xiang Dai, Zongmin Du, W. Ryan Easterday, Haihong Fang, Chenyi Guo, Shanqian Huang, Wanbing Liu, Zhizhen Qi, Yajun Song, Huaiyu Tian, Min Wang, Yarong Wu, Bing Xu, Chao Yang, Jing Yang, Xianwei Yang, Qingwen Zhang, Kjetill S. Jakobsen, Yujiang Zhang, Nils Chr. Stenseth, Ruifu Yang
Publicado 2020

Glucocorticoid Receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor

por Ioanna Petta, Nadia Bougarne, Jolien Vandewalle, Lien Dejager, Sofie Vandevyver, Marlies Ballegeer, Sofie Desmet, Jonathan Thommis, Lode De Cauwer, Sam Lievens, Claude Libert, Jan Tavernier, Karolien De Bosscher
Publicado 2017

The Lyme disease agent co-opts adiponectin receptor-mediated signaling in its arthropod vector

por Xiaotian Tang, Yongguo Cao, Gunjan Arora, Jesse Hwang, Andaleeb Sajid, Courtney L Brown, Sameet Mehta, Alejandro Marín-López, Yu-Min Chuang, Ming-Jie Wu, Hongwei Ma, Utpal Pal, Sukanya Narasimhan, Erol Fikrig
Publicado 2021

EZH2-mediated epigenetic silencing of TIMP2 promotes ovarian cancer migration and invasion

por Xiaoqing Yi, Jianfeng Guo, Jing Guo, Si Sun, Ping Yang, Junjie Wang, Yuan Li, Lisha Xie, Jing Cai, Zehua Wang
Publicado 2017

Does Subjective Cognitive Function Mediate the Effect of Affective Temperaments on Functional Disability in Japanese Adults?

por Toyoshima K, Inoue T, Masuya J, Fujimura Y, Higashi S, Kusumi I
Publicado 2020

RUNX1/RUNX1T1 mediates alternative splicing and reorganises the transcriptional landscape in leukemia

por Vasily V. Grinev, Farnaz Barneh, Ilya M. Ilyushonak, Sirintra Nakjang, Job Smink, Anita van Oort, Richard Clough, Michael Seyani, Hesta McNeill, Mojgan Reza, Natalia Martinez-Soria, Salam A. Assi, Tatsiana V. Ramanouskaya, Constanze Bonifer, Olaf Heidenreich
Publicado 2021

CD39+PD-1+CD8+ T cells mediate metastatic dormancy in breast cancer

por Paulino Tallón de Lara, Héctor Castañón, Marijne Vermeer, Nicolás Núñez, Karina Silina, Bettina Sobottka, Joaquín Urdinez, Virginia Cecconi, Hideo Yagita, Farkhondeh Movahedian Attar, Stefanie Hiltbrunner, Isabelle Glarner, Holger Moch, Sònia Tugues, Burkhard Becher, Maries van den Broek
Publicado 2021