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  1. 3141
    Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation
    “...In cancer, global DNA methylation loss and CpG island hypermethylation are commonly observed. Here...”
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  2. 3142
    Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma
    “... with and without associated STICs and show similar profiles supporting a common origin for all HGSCs....”
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  3. 3143
    A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme
    “... to the development of highly mutated cancers. Here, the authors report that a major consequence of the most common...”
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  4. 3144
    Intrinsic correlation between β-relaxation and spatial heterogeneity in a metallic glass
    “...Beta-relaxation in glasses is commonly attributed to the confined motions of constituent atoms...”
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  5. 3145
    Ancient balancing selection at tan underlies female colour dimorphism in Drosophila erecta
    “...Sexual dimorphism is common in nature. Here, the authors combine population genetics and functional...”
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  6. 3146
    Distinct dynamics of social motivation drive differential social behavior in laboratory rat and mouse strains
    “... social behavior. Here, the authors describe differences in social behavior between commonly used rat...”
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  7. 3147
    The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger
    “...Neutrophils are increased in response to injury and infection but how they form from a common...”
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  8. 3148
    CRISPR–Cas9-targeted fragmentation and selective sequencing enable massively parallel microsatellite analysis
    “...Microsatellite genotyping is a common molecular method of for identification but current methods...”
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  9. 3149
    Regioselective synthesis of C3 alkylated and arylated benzothiophenes
    “...Benzothiophenes are common motifs in bioactive compounds, but selective functionalization at C3...”
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  10. 3150
    Targeted inhibition of the COP9 signalosome for treatment of cancer
    “...Dysregulation of protein degradation by the ubiquitin-proteasome system is a feature commonly...”
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  11. 3151
    Digital logic circuits in yeast with CRISPR-dCas9 NOR gates
    “...The leakiness of commonly used genetic components can make the construction of complex synthetic...”
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  12. 3152
    Charge-specific size-dependent separation of water-soluble organic molecules by fluorinated nanoporous networks
    “...Porous materials for aqueous contaminant removal are common, but there are few examples of size...”
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  13. 3153
    Genome-wide analysis yields new loci associating with aortic valve stenosis
    por Anna Helgadottir, Gudmar Thorleifsson, Solveig Gretarsdottir, Olafur A. Stefansson, Vinicius Tragante, Rosa B. Thorolfsdottir, Ingileif Jonsdottir, Thorsteinn Bjornsson, Valgerdur Steinthorsdottir, Niek Verweij, Jonas B. Nielsen, Wei Zhou, Lasse Folkersen, Andreas Martinsson, Mahyar Heydarpour, Siddharth Prakash, Gylfi Oskarsson, Tomas Gudbjartsson, Arnar Geirsson, Isleifur Olafsson, Emil L. Sigurdsson, Peter Almgren, Olle Melander, Anders Franco-Cereceda, Anders Hamsten, Lars Fritsche, Maoxuan Lin, Bo Yang, Whitney Hornsby, Dongchuan Guo, Chad M. Brummett, Gonçalo Abecasis, Michael Mathis, Dianna Milewicz, Simon C. Body, Per Eriksson, Cristen J. Willer, Kristian Hveem, Christopher Newton-Cheh, J. Gustav Smith, Ragnar Danielsen, Gudmundur Thorgeirsson, Unnur Thorsteinsdottir, Daniel F. Gudbjartsson, Hilma Holm, Kari Stefansson
    Publicado 2018
    “...Aortic valve stenosis (AS) is the most common valvular heart disease. Here the authors identify two...”
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  14. 3154
    Genetic deficiency of NOD2 confers resistance to invasive aspergillosis
    “... show that a common NOD2 genetic variant associated with Crohn’s disease is associated with reduced risk...”
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  15. 3155
    Correct determination of charge transfer state energy from luminescence spectra in organic solar cells
    “... and is commonly accessed by electroluminescence spectra. Here List et al. show that the reliable spectra can only...”
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  16. 3156
    The evolution of cheating in viruses
    “...Cooperation is vulnerable to cheating, and both cooperation and cheating may be especially common...”
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  17. 3157
    Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in preclinical models
    “...C9orf72 expansion mutations are the most common genetic cause of ALS and FTD, which have limited...”
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  18. 3158
    Characterization of transgenic mouse models targeting neuromodulatory systems reveals organizational principles of the dorsal raphe
    “... specificity, anatomical distribution, and connectivity of DR cells targeted by commonly used Cre lines....”
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  19. 3159
    Functional characterization of the 12p12.1 renal cancer-susceptibility locus implicates BHLHE41
    “...A common susceptibility haplotype for renal cell carcinoma is located on chromosome 12p12.1. Here...”
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  20. 3160
    Non-invasive detection of iron deficiency by fluorescence measurement of erythrocyte zinc protoporphyrin in the lip
    “...Iron deficiency, the most common health problem in the world, has required a blood test...”
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