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  1. 50641
    Multiscale heterogeneity in gastric adenocarcinoma evolution is an obstacle to precision medicine
    “... discovery cohort of 9 and a validation cohort of 463 GCs. Multiregional whole-exome sequencing was performed...”
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  2. 50642
    Global diversity of the gene encoding the Pfs25 protein—a Plasmodium falciparum transmission-blocking vaccine candidate
    “... was established. Population genetic analyses were performed to evaluate haplotype and nucleotide diversity...”
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  3. 50643
    Progressive myocardial injury in myotonic dystrophy type II and facioscapulohumeral muscular dystrophy 1: a cardiovascular magnetic resonance follow-up study
    “...% in FSHD1. 1.5 T CMR was performed to assess functional parameters as well as myocardial tissue...”
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  4. 50644
    Long-term visual pathway alterations after elemental mercury poisoning: report of a series of 29 cases
    “... analysis was performed. The correlations between variables also were studied. In addition...”
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  5. 50645
    Nasal spray live attenuated influenza vaccine: the first experience in Italy in children and adolescents during the 2020–21 season
    “... (24.4%). Statistical analysis performed with a multiple regression model, showed that children aged 2–5...”
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  6. 50646
    NAP1L1 interacts with hepatoma-derived growth factor to recruit c-Jun inducing breast cancer growth
    “... and confocal microscopy were performed to explore the detailed molecular mechanism of NAP1L1 in breast cancer...”
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  7. 50647
    DSS-induced inflammation in the colon drives a proinflammatory signature in the brain that is ameliorated by prophylactic treatment with the S100A9 inhibitor paquinimod
    “...-induced neuroinflammation. RNA sequencing was performed to identify transcriptomic changes occurring...”
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  8. 50648
    Sperm chromatin condensation as an in vivo fertility biomarker in bulls: a flow cytometry approach
    “.... This, coupled to the fact that the vast majority of bovine artificial inseminations (AI) are performed using...”
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  9. 50649
    Efficacy of Bushen Huatan Decoction combined with Baduanjin in the treatment of polycystic ovary syndrome with insulin resistance (IR-PCOS), kidney deficiency and phlegm dampness: study protocol for a randomized controlled trial
    “... monitoring of possible adverse events will be performed throughout the trial process. Discussion This trial...”
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  10. 50650
    Dimethyl fumarate prevents acute lung injury related cognitive impairment potentially via reducing inflammation
    por Xiaowei Wang, Yanbo Wang, Haiyan Pan, Ci Yan
    Publicado 2021
    “... was performed before any treatment (0 h) and 6 h after LPS-induction (54 h) to evaluate the cognitive impairment...”
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  11. 50651
    FGD5-AS1 facilitates the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells via targeting the miR-506-3p/BMP7 axis
    por Jun Li, Xingbiao Wu, Yaohua Shi, Hong Zhao
    Publicado 2021
    “...) on osteogenic differentiation. Methods RT-qPCR was performed to detect the expression of FGD5-AS1, miR-506-3p...”
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  12. 50652
    Uncovering Bupi Yishen Formula Pharmacological Mechanisms Against Chronic Kidney Disease by Network Pharmacology and Experimental Validation
    “... of BYF. We performed a comprehensive study by detecting the expression levels of fibrotic...”
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  13. 50653
    Possible role of intravenous administration of mesenchymal stem cells to alleviate interstitial cystitis/bladder pain syndrome in a Toll-like receptor-7 agonist-induced experimental animal model in rat
    “... (RT-PCR) to analyze the mRNA expression levels of inflammatory cytokines were performed. Results...”
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  14. 50654
    A New Strategy for the Rapid Identification and Validation of the Direct Targets of Aconitine-Induced Cardiotoxicity
    por Wei J, Fan S, Yu H, Shu L, Li Y
    Publicado 2021
    “... and predict the direct targets of aconitine. Finally, atomic force microscopy (AFM) imaging was performed...”
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  15. 50655
    Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Attenuate Oxygen-Glucose Deprivation/Reperfusion-Induced Microglial Pyroptosis by Promoting FOXO3a-Dependent Mitophagy
    “..., and Hoechst 33342/PI double staining were performed to detect the pyroptosis of BV-2 cells. Conditioned medium...”
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  16. 50656
    Validation of the Spanish Center for Epidemiological Studies Depression and Zung Self-Rating Depression Scales: a comparative validation study.
    “...) analysis performed. For the CES-D and ZSDS scales, C-α was 0.93 and 0.89 respectively, while MD-Ω was 0.90...”
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  17. 50657
    Activation of haem-oxidized soluble guanylyl cyclase with BAY 60-2770 in human platelets lead to overstimulation of the cyclic GMP signaling pathway.
    “...) integrin activation and Western blot for α1 and β1 sGC subunits were performed. Intracellular calcium...”
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  18. 50658
    Detection of antibodies to erythropoietin-based drugs: is it possible to create the universal test system?
    “... not receive recombinant human EPO (rhEPO) were studied for comparative analysis. ELISA assay was performed...”
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  19. 50659
    Altered glucose homeostasis is associated with increased serum apelin levels in type 2 diabetes mellitus.
    “... of serum apelin levels independently from age and BMI. Bariatric surgery performed in a subgroup of obese...”
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  20. 50660
    CloudDOE: a user-friendly tool for deploying Hadoop clouds and analyzing high-throughput sequencing data with MapReduce.
    “...-friendly graphical interface, thus liberating scientists from having to perform complicated operational...”
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