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  1. 2161
    The Impact of DNA Polymerase and Number of Rounds of Amplification in PCR on 16S rRNA Gene Sequence Data
    por Marc A. Sze, Patrick D. Schloss
    Publicado 2019
    Materias: “...16S rRNA gene...”
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  2. 2162
    Simultaneous identification of DNA and RNA viruses present in pig faeces using process-controlled deep sequencing.
    “... fraction of viral particles from pig faeces. The genomes of the purified DNA and RNA viruses were...”
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  3. 2163
    MicroRNA-152 mediates DNMT1-regulated DNA methylation in the estrogen receptor α gene.
    “..., SHXXT) could exert a therapeutic effect on microRNA, DNMT and ERα methylation.<h4>Methodology/principal...”
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  4. 2164
    Transcriptome analysis of Houttuynia cordata Thunb. by Illumina paired-end RNA sequencing and SSR marker discovery.
    “... over 56 million sequencing reads from H. cordata mRNA. Subsequent de novo assembly yielded 63,954...”
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  5. 2165
    The utility of shallow RNA-Seq for documenting differential gene expression in genes with high and low levels of expression.
    “...The sequencing depth necessary for documenting differential gene expression using RNA-Seq has been...”
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  6. 2166
    Cardiac pathologies in mouse loss of imprinting models are due to misexpression of H19 long noncoding RNA
    Materias: “...H19 lncRNA...”
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  7. 2167
    The m6A RNA Modification Modulates Gene Expression and Fibrosis-Related Pathways in Hypertrophic Scar
    “... and RNA sequencing, and subsequently bioinformatics analysis was performed. The m6A-related RNA...”
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  8. 2168
    Exosomal cargo including microRNA regulates sensory neuron to macrophage communication after nerve trauma
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  9. 2169
    Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer
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  10. 2170
    Chromosome-associated RNA–protein complexes promote pairing of homologous chromosomes during meiosis in Schizosaccharomyces pombe
    “... the authors reveal in S. pombe the role of lncRNA–protein complexes during the pairing of homologues...”
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  11. 2171
    N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis
    “.... Here the authors report that N6-methyladenosine mRNA methyltransferase complex stimulates...”
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  12. 2172
    Metal ions and sugar puckering balance single-molecule kinetic heterogeneity in RNA and DNA tertiary contacts
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  13. 2173
    Realistic in silico generation and augmentation of single-cell RNA-seq data using generative adversarial networks
    “... introduce a method to generate realistic scRNA-seq data using GANs that learn gene expression dependencies...”
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  14. 2174
    Predicting bacterial infection outcomes using single cell RNA-sequencing analysis of human immune cells
    “... infections. Here, Avraham and colleagues present a deconvolution algorithm that uses single-cell RNA and bulk...”
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  15. 2175
    The RNA helicase DHX34 functions as a scaffold for SMG1-mediated UPF1 phosphorylation
    “...UPF1 is a central Nonsense-mediated mRNA decay—(NMD), a mechanism to degrade mRNAs containing...”
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  16. 2176
    Urine miRNA signature as a potential non-invasive diagnostic and prognostic biomarker in cervical cancer
    “... but analysis of miRNA in urine is limited. We investigated the expression of selected miRNAs in the paired...”
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  17. 2177
    A live imaging system to analyze spatiotemporal dynamics of RNA polymerase II modification in Arabidopsis thaliana
    “... of RNA polymerase II modification in single cells in Arabidopsis thaliana. This approach potentially...”
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  18. 2178
    Single-molecule, full-length transcript isoform sequencing reveals disease-associated RNA isoforms in cardiomyocytes
    “...Alternative splicing generates RNA isoforms that contribute to phenotypic diversity. Here...”
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  19. 2179
    Docking sites inside Cas9 for adenine base editing diversification and RNA off-target elimination
    “...Current SpCas9 adenine base editors that minimise RNA off-target activities have constrained...”
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  20. 2180
    Optimized CRISPR guide RNA design for two high-fidelity Cas9 variants by deep learning
    “...Application of highly specific Cas9 variants can be restricted by the design of the guide RNA. Here...”
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