Drug and disease signature integration identifies synergistic combinations in glioblastoma

por Vasileios Stathias, Anna M. Jermakowicz, Marie E. Maloof, Michele Forlin, Winston Walters, Robert K. Suter, Michael A. Durante, Sion L. Williams, J. William Harbour, Claude-Henry Volmar, Nicholas J. Lyons, Claes Wahlestedt, Regina M. Graham, Michael E. Ivan, Ricardo J. Komotar, Jann N. Sarkaria, Aravind Subramanian, Todd R. Golub, Stephan C. Schürer, Nagi G. Ayad
Publicado 2018

Immunogenicity and reactogenicity of 2009 influenza A (H1N1) inactivated monovalent non-adjuvanted vaccine in elderly and immunocompromised patients.

por João L Miraglia, Edson Abdala, Paulo M Hoff, André M Luiz, Danise S Oliveira, Carla G S Saad, Ieda M M Laurindo, Ana T R Viso, Angela Tayra, Lígia C Pierrotti, Luiz S Azevedo, Lúcia Maria A Campos, Nádia E Aikawa, Maria do Carmo S T Timenetsky, Expedito Luna, Maria Regina A Cardoso, José da S Guedes, Isaias Raw, Jorge Kalil, Alexander R Precioso
Publicado 2011

β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions

por Lu Zhu, Joana Almaça, Prasanna K. Dadi, Hao Hong, Wataru Sakamoto, Mario Rossi, Regina J. Lee, Nicholas C. Vierra, Huiyan Lu, Yinghong Cui, Sara M. McMillin, Nicole A. Perry, Vsevolod V. Gurevich, Amy Lee, Bryan Kuo, Richard D. Leapman, Franz M. Matschinsky, Nicolai M. Doliba, Nikhil M. Urs, Marc G. Caron, David A. Jacobson, Alejandro Caicedo, Jürgen Wess
Publicado 2017

Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information

por Sebastian Guelfi, Karishma D’Sa, Juan A. Botía, Jana Vandrovcova, Regina H. Reynolds, David Zhang, Daniah Trabzuni, Leonardo Collado-Torres, Andrew Thomason, Pedro Quijada Leyton, Sarah A. Gagliano Taliun, Mike A. Nalls, International Parkinson’s Disease Genomics Consortium (IPDGC), UK Brain Expression Consortium (UKBEC), Kerrin S. Small, Colin Smith, Adaikalavan Ramasamy, John Hardy, Michael E. Weale, Mina Ryten
Publicado 2020

Recomendaciones para el estudio y manejo farmacológico en pacientes adultos con sospecha de infección por SARS-CoV-2 (COVID-19)

por Pérez Godoy,Jorge, Rosales Chacón,Ruth, Bernal Ortiz,Fernando, Luengo Messen,Cecilia, Arancibia Henríquez,José Miguel, Pavez Azurmendi,Daniela, González Muñoz,Claudio, Arancibia Hernández,Francisco, Riquelme Oyarzún,Raúl, Pérez Pérez,Regina, Acuña Ávila,Mirta, Chanqueo Cornejo,Leonardo, Regueira Heskia,Tomás, Fuenzalida,Luz María, Hernández Mazurek,Rubén, Arias Lucero,Mariana, Impellizzeri Navarro,Paula, Paredes Kunst,Cristian, Pinto Claude,María Eugenia
Publicado 2020

Oxidative stress and modification of renal vascular permeability are associated with acute kidney injury during P. berghei ANKA infection.

por Rosa Maria Elias, Matheus Correa-Costa, Claudiene Rodrigues Barreto, Reinaldo Correia Silva, Caroline Y Hayashida, Angela Castoldi, Giselle Martins Gonçalves, Tarcio Teodoro Braga, Renato Barboza, Francisco José Rios, Alexandre Castro Keller, Marcos Antonio Cenedeze, Meire Ioshie Hyane, Maria Regina D'Império-Lima, Antônio Martins Figueiredo-Neto, Marlene Antônia Reis, Cláudio Romero Farias Marinho, Alvaro Pacheco-Silva, Niels Olsen Saraiva Câmara
Publicado 2012

Multiple Risk Factors for Heart Disease: A Challenge to the Ethnopharmacological Use of Croton urucurana Baill.

por Priscila Megda João Job Zago, Gustavo Ratti da Silva, Eduarda Carolina Amaral, Lorena Neris Barboza, Fernanda de Abreu Braga, Bethânia Rosa Lorençone, Aline Aparecida Macedo Marques, Karyne Garcia Tafarelo Moreno, Patrícia Regina Terço Leite, Alan de Almeida Veiga, Lauro Mera de Souza, Roosevelt Isaias Carvalho Souza, Ariany Carvalho dos Santos, João Tadeu Ribeiro-Paes, Arquimedes Gasparotto Junior, Francislaine Aparecida dos Reis Lívero
Publicado 2021

Epidemiological investigation reveals local transmission of SARS-CoV-2 lineage P.1 in Southern Brazil

por Richard Steiner Salvato, Tatiana Schäffer Gregianini, Aline Alves Scarpellini Campos, Lara Villanova Crescente, Marcelo Jostmeier Vallandro, Tani Maria Schilling Ranieri, Sabrina Vizeu, Letícia Garay Martins, Eduardo Viegas da Silva, Ellen Regina Pedroso, Andreia Burille, Ludmila Fiorenzano Baethgen, Sun Hee Schiefelbein, Taís Raquel Marcon Machado, Irina Marieta Becker, Raquel Ramos, Cláudia Fasolo Piazza, Zenaida Marion Alves Nunes, Cynthia Goulart Molina Bastos Bastos
Publicado 2021

European ancestry predominates in neuromyelitis optica and multiple sclerosis patients from Brazil.

por Doralina Guimarães Brum, Marcelo Rizzatti Luizon, Antônio Carlos Santos, Marco Aurélio Lana-Peixoto, Cristiane Franklin Rocha, Maria Lucia Brito, Enedina Maria Lobato de Oliveira, Denis Bernardi Bichuetti, Alberto Alan Gabbai, Denise Sisterolli Diniz, Damacio Ramon Kaimen-Maciel, Elizabeth Regina Comini-Frota, Claudia E Vieira Wiezel, Yara Costa Netto Muniz, Roberta Martins da Silva Costa, Celso Teixeira Mendes-Junior, Eduardo Antônio Donadi, Amilton Antunes Barreira, Aguinaldo Luiz Simões
Publicado 2013

Correction: Corrigendum: Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan

por Markus Schosserer, Nadege Minois, Tina B. Angerer, Manuela Amring, Hanna Dellago, Eva Harreither, Alfonso Calle-Perez, Andreas Pircher, Matthias Peter Gerstl, Sigrid Pfeifenberger, Clemens Brandl, Markus Sonntagbauer, Albert Kriegner, Angela Linder, Andreas Weinhäusel, Thomas Mohr, Matthias Steiger, Diethard Mattanovich, Mark Rinnerthaler, Thomas Karl, Sunny Sharma, Karl-Dieter Entian, Martin Kos, Michael Breitenbach, Iain B. H. Wilson, Norbert Polacek, Regina Grillari-Voglauer, Lore Breitenbach-Koller, Johannes Grillari
Publicado 2016

Phospholamban antisense oligonucleotides improve cardiac function in murine cardiomyopathy

por Niels Grote Beverborg, Daniela Später, Ralph Knöll, Alejandro Hidalgo, Steve T. Yeh, Zaher Elbeck, Herman H. W. Silljé, Tim R. Eijgenraam, Humam Siga, Magdalena Zurek, Malin Palmér, Susanne Pehrsson, Tamsin Albery, Nils Bomer, Martijn F. Hoes, Cornelis J. Boogerd, Michael Frisk, Eva van Rooij, Sagar Damle, William E. Louch, Qing-Dong Wang, Regina Fritsche-Danielson, Kenneth R. Chien, Kenny M. Hansson, Adam E. Mullick, Rudolf A. de Boer, Peter van der Meer
Publicado 2021

Humans Surviving Cholera Develop Antibodies against <named-content content-type="genus-species">Vibrio cholerae</named-content> O-Specific Polysaccharide That Inhibit Pathogen Moti...

por Richelle C. Charles, Meagan Kelly, Jenny M. Tam, Aklima Akter, Motaher Hossain, Kamrul Islam, Rajib Biswas, Mohammad Kamruzzaman, Fahima Chowdhury, Ashraful I. Khan, Daniel T. Leung, Ana Weil, Regina C. LaRocque, Taufiqur Rahman Bhuiyan, Atiqur Rahman, Leslie M. Mayo-Smith, Rachel L. Becker, Jatin M. Vyas, Christina S. Faherty, Kourtney P. Nickerson, Samantha Giffen, Alaina S. Ritter, Matthew K. Waldor, Peng Xu, Pavol Kováč, Stephen B. Calderwood, Robert C. Kauffman, Jens Wrammert, Firdausi Qadri, Jason B. Harris, Edward T. Ryan
Publicado 2020

New therapeutic target for pediatric anaplastic ependymoma control: study of anti-tumor activity by a Kunitz-type molecule, Amblyomin-X

por Lorena Favaro Pavon, David Capper, Tatiana Tais Sibov, Silvia Regina Caminada de Toledo, Ulrich-W. Thomale, Jean Gabriel de Souza, Francisco Romero Cabral, Carolina Maria Berra, Marcos Devanir Silva da Costa, Jardel Mendonça Niçacio, Patrícia Alessandra Dastoli, Daniela Mara de Oliveira, Suzana M. F. Malheiros, Edgar Ferreira da Cruz, Jackeline Moraes Malheiros, Sérgio Mascarenhas de Oliveira, Nasjla Saba Silva, Antonio Sérgio Petrilli, Andrea Maria Cappellano, Milena Colò Brunialti, Reinaldo Salomão, Manoel A. de Paiva Neto, Ana Marisa Chudzinski-Tavassi, Sérgio Cavalheiro
Publicado 2019

CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary

por Yibo Xue, Brian Meehan, Elizabeth Macdonald, Sriram Venneti, Xue Qing D. Wang, Leora Witkowski, Petar Jelinic, Tim Kong, Daniel Martinez, Geneviève Morin, Michelle Firlit, Atefeh Abedini, Radia M. Johnson, Regina Cencic, Jay Patibandla, Hongbo Chen, Andreas I. Papadakis, Aurelie Auguste, Iris de Rink, Ron M. Kerkhoven, Nicholas Bertos, Walter H. Gotlieb, Blaise A. Clarke, Alexandra Leary, Michael Witcher, Marie-Christine Guiot, Jerry Pelletier, Josée Dostie, Morag Park, Alexander R. Judkins, Ralf Hass, Douglas A. Levine, Janusz Rak, Barbara Vanderhyden, William D. Foulkes, Sidong Huang
Publicado 2019

A functionally significant SNP in TP53 and breast cancer risk in African-American women

por Maureen E. Murphy, Song Liu, Song Yao, Dezheng Huo, Qin Liu, Sonia C. Dolfi, Kim M. Hirshfield, Chi-Chen Hong, Qiang Hu, Andrew F. Olshan, Temidayo O. Ogundiran, Clement Adebamowo, Susan M. Domchek, Katherine L. Nathanson, Barbara Nemesure, Stefan Ambs, William J. Blot, Ye Feng, Esther M. John, Leslie Bernstein, Wei Zheng, Jennifer J. Hu, Regina G. Ziegler, Sarah Nyante, Sue A. Ingles, Michael F. Press, Sandra L. Deming, Jorge L. Rodriguez-Gil, Christopher A. Haiman, Olufunmilayo I. Olopade, Kathryn L. Lunetta, Julie R. Palmer, Christine B. Ambrosone
Publicado 2017

Unstable TTTTA/TTTCA expansions in MARCH6 are associated with Familial Adult Myoclonic Epilepsy type 3

por Rahel T. Florian, Florian Kraft, Elsa Leitão, Sabine Kaya, Stephan Klebe, Eloi Magnin, Anne-Fleur van Rootselaar, Julien Buratti, Theresa Kühnel, Christopher Schröder, Sebastian Giesselmann, Nikolai Tschernoster, Janine Altmueller, Anaide Lamiral, Boris Keren, Caroline Nava, Delphine Bouteiller, Sylvie Forlani, Ludmila Jornea, Regina Kubica, Tao Ye, Damien Plassard, Bernard Jost, Vincent Meyer, Jean-François Deleuze, Yannick Delpu, Mario D. M. Avarello, Lisanne S. Vijfhuizen, Gabrielle Rudolf, Edouard Hirsch, Thessa Kroes, Philipp S. Reif, Felix Rosenow, Christos Ganos, Marie Vidailhet, Lionel Thivard, Alexandre Mathieu, Thomas Bourgeron, Ingo Kurth, Haloom Rafehi, Laura Steenpass, Bernhard Horsthemke, FAME consortium, Eric LeGuern, Karl Martin Klein, Pierre Labauge, Mark F. Bennett, Melanie Bahlo, Jozef Gecz, Mark A. Corbett, Marina A. J. Tijssen, Arn M. J. M. van den Maagdenberg, Christel Depienne
Publicado 2019

Circulating sex hormones in relation to anthropometric, sociodemographic and behavioural factors in an international dataset of 12,300 men.

por Eleanor L Watts, Paul N Appleby, Demetrius Albanes, Amanda Black, June M Chan, Chu Chen, Piera M Cirillo, Barbara A Cohn, Michael B Cook, Jenny L Donovan, Luigi Ferrucci, Cedric F Garland, Graham G Giles, Phyllis J Goodman, Laurel A Habel, Christopher A Haiman, Jeff M P Holly, Robert N Hoover, Rudolf Kaaks, Paul Knekt, Laurence N Kolonel, Tatsuhiko Kubo, Loïc Le Marchand, Tapio Luostarinen, Robert J MacInnis, Hanna O Mäenpää, Satu Männistö, E Jeffrey Metter, Roger L Milne, Abraham M Y Nomura, Steven E Oliver, J Kellogg Parsons, Petra H Peeters, Elizabeth A Platz, Elio Riboli, Fulvio Ricceri, Sabina Rinaldi, Harri Rissanen, Norie Sawada, Catherine A Schaefer, Jeannette M Schenk, Frank Z Stanczyk, Meir Stampfer, Pär Stattin, Ulf-Håkan Stenman, Anne Tjønneland, Antonia Trichopoulou, Ian M Thompson, Shoichiro Tsugane, Lars Vatten, Alice S Whittemore, Regina G Ziegler, Naomi E Allen, Timothy J Key, Ruth C Travis
Publicado 2017

Cross-ancestry GWAS meta-analysis identifies six breast cancer loci in African and European ancestry women

por Babatunde Adedokun, Zhaohui Du, Guimin Gao, Thomas U. Ahearn, Kathryn L. Lunetta, Gary Zirpoli, Jonine Figueroa, Esther M. John, Leslie Bernstein, Wei Zheng, Jennifer J. Hu, Regina G. Ziegler, Sarah Nyante, Elisa V. Bandera, Sue A. Ingles, Michael F. Press, Sandra L. Deming-Halverson, Jorge L. Rodriguez-Gil, Song Yao, Temidayo O. Ogundiran, Oladosu Ojengbede, William Blot, Melissa A. Troester, Katherine L. Nathanson, Anselm Hennis, Barbara Nemesure, Stefan Ambs, Peter N. Fiorica, Lara E. Sucheston-Campbell, Jeannette T. Bensen, Lawrence H. Kushi, Gabriela Torres-Mejia, Donglei Hu, Laura Fejerman, Manjeet K. Bolla, Joe Dennis, Alison M. Dunning, Douglas F. Easton, Kyriaki Michailidou, Paul D. P. Pharoah, Qin Wang, Dale P. Sandler, Jack A. Taylor, Katie M. O’Brien, Cari M. Kitahara, Adeyinka G. Falusi, Chinedum Babalola, Joel Yarney, Baffour Awuah, Beatrice Addai-Wiafe, The GBHS Study Team, Stephen J. Chanock, Andrew F. Olshan, Christine B. Ambrosone, David V. Conti, Elad Ziv, Olufunmilayo I. Olopade, Montserrat Garcia-Closas, Julie R. Palmer, Christopher A. Haiman, Dezheng Huo
Publicado 2021

Evidence for reductive genome evolution and lateral acquisition of virulence functions in two Corynebacterium pseudotuberculosis strains.

por Jerônimo C Ruiz, Vívian D'Afonseca, Artur Silva, Amjad Ali, Anne C Pinto, Anderson R Santos, Aryanne A M C Rocha, Débora O Lopes, Fernanda A Dorella, Luis G C Pacheco, Marcília P Costa, Meritxell Z Turk, Núbia Seyffert, Pablo M R O Moraes, Siomar C Soares, Sintia S Almeida, Thiago L P Castro, Vinicius A C Abreu, Eva Trost, Jan Baumbach, Andreas Tauch, Maria Paula C Schneider, John McCulloch, Louise T Cerdeira, Rommel T J Ramos, Adhemar Zerlotini, Anderson Dominitini, Daniela M Resende, Elisângela M Coser, Luciana M Oliveira, André L Pedrosa, Carlos U Vieira, Cláudia T Guimarães, Daniela C Bartholomeu, Diana M Oliveira, Fabrício R Santos, Élida Mara Rabelo, Francisco P Lobo, Glória R Franco, Ana Flávia Costa, Ieso M Castro, Sílvia Regina Costa Dias, Jesus A Ferro, José Miguel Ortega, Luciano V Paiva, Luiz R Goulart, Juliana Franco Almeida, Maria Inês T Ferro, Newton P Carneiro, Paula R K Falcão, Priscila Grynberg, Santuza M R Teixeira, Sérgio Brommonschenkel, Sérgio C Oliveira, Roberto Meyer, Robert J Moore, Anderson Miyoshi, Guilherme C Oliveira, Vasco Azevedo
Publicado 2011