Organocatalytic enantioselective dearomatization of thiophenes by 1,10-conjugate addition of indole imine methides

por Xingguang Li, Meng Duan, Peiyuan Yu, K. N. Houk, Jianwei Sun
Publicado 2021

PD-L1+ and XCR1+ dendritic cells are region-specific regulators of gut homeostasis

por Thais G. Moreira, Davide Mangani, Laura M. Cox, Jeffrey Leibowitz, Eduardo. L. C. Lobo, Mariana A. Oliveira, Christian D. Gauthier, Brenda N. Nakagaki, Valerie Willocq, Anya Song, Lydia Guo, David C. A. Lima, Gopal Murugaiyan, Oleg Butovsky, Galina Gabriely, Ana C. Anderson, Rafael M. Rezende, Ana Maria C. Faria, Howard L. Weiner
Publicado 2021

Defining the molecular mechanisms of the mitochondrial permeability transition through genetic manipulation of F-ATP synthase

por Andrea Carrer, Ludovica Tommasin, Justina Šileikytė, Francesco Ciscato, Riccardo Filadi, Andrea Urbani, Michael Forte, Andrea Rasola, Ildikò Szabò, Michela Carraro, Paolo Bernardi
Publicado 2021

B-SOiD, an open-source unsupervised algorithm for identification and fast prediction of behaviors

por Alexander I. Hsu, Eric A. Yttri
Publicado 2021

A hybrid molecular peapod of sp2- and sp3-nanocarbons enabling ultrafast terahertz rotations

por Taisuke Matsuno, Seiya Terasaki, Kanako Kogashi, Ryosuke Katsuno, Hiroyuki Isobe
Publicado 2021

Acquisition of aneuploidy drives mutant p53-associated gain-of-function phenotypes

por Lindsay N. Redman-Rivera, Timothy M. Shaver, Hailing Jin, Clayton B. Marshall, Johanna M. Schafer, Quanhu Sheng, Rachel A. Hongo, Kathryn E. Beckermann, Ferrin C. Wheeler, Brian D. Lehmann, Jennifer A. Pietenpol
Publicado 2021

Li-ion storage properties of two-dimensional titanium-carbide synthesized via fast one-pot method in air atmosphere

por Guoliang Ma, Hui Shao, Jin Xu, Ying Liu, Qing Huang, Pierre-Louis Taberna, Patrice Simon, Zifeng Lin
Publicado 2021

PLK1 inhibition exhibits strong anti-tumoral activity in CCND1-driven breast cancer metastases with acquired palbociclib resistance

por Elodie Montaudon, Joanna Nikitorowicz-Buniak, Laura Sourd, Ludivine Morisset, Rania El Botty, Léa Huguet, Ahmed Dahmani, Pierre Painsec, Fariba Nemati, Sophie Vacher, Walid Chemlali, Julien Masliah-Planchon, Sophie Château-Joubert, Camilla Rega, Mariana Ferreira Leal, Nikiana Simigdala, Sunil Pancholi, Ricardo Ribas, André Nicolas, Didier Meseure, Anne Vincent-Salomon, Cécile Reyes, Audrey Rapinat, David Gentien, Thibaut Larcher, Mylène Bohec, Sylvain Baulande, Virginie Bernard, Didier Decaudin, Florence Coussy, Muriel Le Romancer, Guillaume Dutertre, Zakia Tariq, Paul Cottu, Keltouma Driouch, Ivan Bièche, Lesley-Ann Martin, Elisabetta Marangoni
Publicado 2020

Insights into projected changes in marine heatwaves from a high-resolution ocean circulation model

por Hakase Hayashida, Richard J. Matear, Peter G. Strutton, Xuebin Zhang
Publicado 2020

Small-molecule polymerase inhibitor protects non-human primates from measles and reduces shedding

por Kevin Wittwer, Danielle E. Anderson, Kristin Pfeffermann, Robert M. Cox, Josef D. Wolf, Sabine Santibanez, Annette Mankertz, Roland Plesker, Zachary M. Sticher, Alexander A. Kolkykhalov, Michael G. Natchus, Christian K. Pfaller, Richard K. Plemper, Veronika von Messling
Publicado 2021

An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction

por Leo Hanke, Laura Vidakovics Perez, Daniel J. Sheward, Hrishikesh Das, Tim Schulte, Ainhoa Moliner-Morro, Martin Corcoran, Adnane Achour, Gunilla B. Karlsson Hedestam, B. Martin Hällberg, Ben Murrell, Gerald M. McInerney
Publicado 2020

Cytotoxic T cells are able to efficiently eliminate cancer cells by additive cytotoxicity

por Bettina Weigelin, Annemieke Th. den Boer, Esther Wagena, Kelly Broen, Harry Dolstra, Rob J. de Boer, Carl G. Figdor, Johannes Textor, Peter Friedl
Publicado 2021

A comprehensive risk score for effective risk stratification and screening of nasopharyngeal carcinoma

por Xiang Zhou, Su-Mei Cao, Yong-Lin Cai, Xiao Zhang, Shanshan Zhang, Guo-Fei Feng, Yufeng Chen, Qi-Sheng Feng, Yijun Chen, Ellen T. Chang, Zhonghua Liu, Hans-Olov Adami, Jianjun Liu, Weimin Ye, Zhe Zhang, Yi-Xin Zeng, Miao Xu
Publicado 2021

Improved modeling of human AD with an automated culturing platform for iPSC neurons, astrocytes and microglia

por Reina Bassil, Kenneth Shields, Kevin Granger, Ivan Zein, Shirley Ng, Ben Chih
Publicado 2021

Functional characterization of T2D-associated SNP effects on baseline and ER stress-responsive β cell transcriptional activation

por Shubham Khetan, Susan Kales, Romy Kursawe, Alexandria Jillette, Jacob C. Ulirsch, Steven K. Reilly, Duygu Ucar, Ryan Tewhey, Michael L. Stitzel
Publicado 2021

Circadian clock mechanism driving mammalian photoperiodism

por S. H. Wood, M. M. Hindle, Y. Mizoro, Y. Cheng, B. R. C. Saer, K. Miedzinska, H. C. Christian, N. Begley, J. McNeilly, A. S. McNeilly, S. L. Meddle, D. W. Burt, A. S. I. Loudon
Publicado 2020

A quantitative model predicts how m6A reshapes the kinetic landscape of nucleic acid hybridization and conformational transitions

por Bei Liu, Honglue Shi, Atul Rangadurai, Felix Nussbaumer, Chia-Chieh Chu, Kevin Andreas Erharter, David A. Case, Christoph Kreutz, Hashim M. Al-Hashimi
Publicado 2021

Publisher Correction: Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination

por Lars Muhl, Guillem Genové, Stefanos Leptidis, Jianping Liu, Liqun He, Giuseppe Mocci, Ying Sun, Sonja Gustafsson, Byambajav Buyandelger, Indira V. Chivukula, Åsa Segerstolpe, Elisabeth Raschperger, Emil M. Hansson, Johan L. M. Björkegren, Xiao-Rong Peng, Michael Vanlandewijck, Urban Lendahl, Christer Betsholtz
Publicado 2020

Distinct Cdk9-phosphatase switches act at the beginning and end of elongation by RNA polymerase II

por Pabitra K. Parua, Sampada Kalan, Bradley Benjamin, Miriam Sansó, Robert P. Fisher
Publicado 2020

Author Correction: Reef Cover, a coral reef classification for global habitat mapping from remote sensing

por Emma V. Kennedy, Chris M. Roelfsema, Mitchell B. Lyons, Eva M. Kovacs, Rodney Borrego-Acevedo, Meredith Roe, Stuart R. Phinn, Kirk Larsen, Nicholas J. Murray, Doddy Yuwono, Jeremy Wolff, Paul Tudman
Publicado 2021