USP11 controls R-loops by regulating senataxin proteostasis

por Mateusz Jurga, Arwa A. Abugable, Alastair S. H. Goldman, Sherif F. El-Khamisy
Publicado 2021

Metallic nanocrystals with low angle grain boundary for controllable plastic reversibility

por Qi Zhu, Qishan Huang, Cao Guang, Xianghai An, Scott X. Mao, Wei Yang, Ze Zhang, Huajian Gao, Haofei Zhou, Jiangwei Wang
Publicado 2020

A pig BodyMap transcriptome reveals diverse tissue physiologies and evolutionary dynamics of transcription

por Long Jin, Qianzi Tang, Silu Hu, Zhongxu Chen, Xuming Zhou, Bo Zeng, Yuhao Wang, Mengnan He, Yan Li, Lixuan Gui, Linyuan Shen, Keren Long, Jideng Ma, Xun Wang, Zhengli Chen, Yanzhi Jiang, Guoqing Tang, Li Zhu, Fei Liu, Bo Zhang, Zhiqing Huang, Guisen Li, Diyan Li, Vadim N. Gladyshev, Jingdong Yin, Yiren Gu, Xuewei Li, Mingzhou Li
Publicado 2021

Tailored cobalt-salen complexes enable electrocatalytic intramolecular allylic C–H functionalizations

por Chen-Yan Cai, Zheng-Jian Wu, Ji-Ying Liu, Ming Chen, Jinshuai Song, Hai-Chao Xu
Publicado 2021

Designed and biologically active protein lattices

por Shih-Ting Wang, Brian Minevich, Jianfang Liu, Honghu Zhang, Dmytro Nykypanchuk, James Byrnes, Wu Liu, Lev Bershadsky, Qun Liu, Tong Wang, Gang Ren, Oleg Gang
Publicado 2021

Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding

por Fangjun Yu, Zhigang Wang, Tianpeng Zhang, Xun Chen, Haiman Xu, Fei Wang, Lianxia Guo, Min Chen, Kaisheng Liu, Baojian Wu
Publicado 2021

Adoptive immunotherapy with transient anti-CD4 treatment enhances anti-tumor response by increasing IL-18Rαhi CD8+ T cells

por Seon-Hee Kim, Eunjung Cho, Yu I. Kim, Chungyong Han, Beom K. Choi, Byoung S. Kwon
Publicado 2021

Central circuit mechanisms of itch

por Xiao-Jun Chen, Yan-Gang Sun
Publicado 2020

Structural insights into an atypical secretory pathway kinase crucial for Toxoplasma gondii invasion

por Gaëlle Lentini, Rouaa Ben Chaabene, Oscar Vadas, Chandra Ramakrishnan, Budhaditya Mukherjee, Ved Mehta, Matteo Lunghi, Jonas Grossmann, Bohumil Maco, Rémy Visentin, Adrian B. Hehl, Volodymyr M. Korkhov, Dominique Soldati-Favre
Publicado 2021

A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus

por Christopher J. Harding, Simona G. Huwiler, Hannah Somers, Carey Lambert, Luke J. Ray, Rob Till, Georgina Taylor, Patrick J. Moynihan, R. Elizabeth Sockett, Andrew L. Lovering
Publicado 2020

Optical gap and fundamental gap of oligoynes and carbyne

por Johannes Zirzlmeier, Stephen Schrettl, Jan C. Brauer, Emmanuel Contal, Laurent Vannay, Éric Brémond, Eike Jahnke, Dirk M. Guldi, Clémence Corminboeuf, Rik R. Tykwinski, Holger Frauenrath
Publicado 2020

Evolutionarily informed machine learning enhances the power of predictive gene-to-phenotype relationships

por Chia-Yi Cheng, Ying Li, Kranthi Varala, Jessica Bubert, Ji Huang, Grace J. Kim, Justin Halim, Jennifer Arp, Hung-Jui S. Shih, Grace Levinson, Seo Hyun Park, Ha Young Cho, Stephen P. Moose, Gloria M. Coruzzi
Publicado 2021

High-efficiency broadband achromatic metalens for near-IR biological imaging window

por Yujie Wang, Qinmiao Chen, Wenhong Yang, Ziheng Ji, Limin Jin, Xing Ma, Qinghai Song, Alexandra Boltasseva, Jiecai Han, Vladimir M. Shalaev, Shumin Xiao
Publicado 2021

PD-L1 on dendritic cells attenuates T cell activation and regulates response to immune checkpoint blockade

por Qi Peng, Xiangyan Qiu, Zihan Zhang, Silin Zhang, Yuanyuan Zhang, Yong Liang, Jingya Guo, Hua Peng, Mingyi Chen, Yang-Xin Fu, Haidong Tang
Publicado 2020

Captivity and the co-diversification of great ape microbiomes

por Alex H. Nishida, Howard Ochman
Publicado 2021

Synthetic hydrogel nanoparticles for sepsis therapy

por Hiroyuki Koide, Anna Okishima, Yu Hoshino, Yuri Kamon, Keiichi Yoshimatsu, Kazuhiro Saito, Ikumi Yamauchi, Saki Ariizumi, Yuqi Zhou, Ting-Hui Xiao, Keisuke Goda, Naoto Oku, Tomohiro Asai, Kenneth J. Shea
Publicado 2021

Whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domestication

por Prasun Dutta, Andrea Talenti, Rachel Young, Siddharth Jayaraman, Rebecca Callaby, Santosh Kumar Jadhav, Velu Dhanikachalam, Mayakannan Manikandan, Bhim B. Biswa, Wai Y. Low, John L. Williams, Elizabeth Cook, Phil Toye, Eileen Wall, Appolinaire Djikeng, Karen Marshall, Alan L. Archibald, Suresh Gokhale, Satish Kumar, David A. Hume, James G. D. Prendergast
Publicado 2020

Berberine is an insulin secretagogue targeting the KCNH6 potassium channel

por Miao-Miao Zhao, Jing Lu, Sen Li, Hao Wang, Xi Cao, Qi Li, Ting-Ting Shi, Kohichi Matsunaga, Chen Chen, Haixia Huang, Testuro Izumi, Jin-Kui Yang
Publicado 2021

Update to the dataset of cerebral ischemia in juvenile pigs with evoked potentials

por Martin G. Frasch, Bernd Walter, Christoph Anders, Reinhard Bauer
Publicado 2021

MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme

por Yingzhong Li, Nikola A. Ivica, Ting Dong, Dimitrios P. Papageorgiou, Yanpu He, Douglas R. Brown, Marianna Kleyman, Guangan Hu, Walter W. Chen, Lucas B. Sullivan, Amanda Del Rosario, Paula T. Hammond, Matthew G. Vander Heiden, Jianzhu Chen
Publicado 2020