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  1. 2521
    Origins of Transcriptional Transition: Balance between Upstream and Downstream Regulatory Gene Sequences
    “... frequency and sizes. Independent activation of the regulatory-gene sequence does not produce bimodal...”
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  2. 2522
    Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure.
    “... Env with deletion of these loops. Strikingly, in SIV CP-MAC, a CD4-independent strain, trimeric Env...”
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  3. 2523
    Fatal outcome in bacteremia is characterized by high plasma cell free DNA concentration and apoptotic DNA fragmentation: a prospective cohort study.
    “... for fatal disease. High cf-DNA (>1.52 ug/ml) remained an independent risk factor for case fatality in a...”
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  4. 2524
    Assessing the performance of a computer-based policy model of HIV and AIDS.
    “... to prevent HIV complications independent of virologic suppression. Good-fitting parameter sets required...”
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  5. 2525
    Alkylation base damage is converted into repairable double-strand breaks and complex intermediates in G2 cells lacking AP endonuclease.
    “... in G2-arrested cells, i.e., S-phase independent. These derived DSBs were observed in apn1/2...”
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  6. 2526
    Risk Factors for Pericallosal Artery Aneurysm Rupture Based on Morphological Computer-Assisted Semiautomated Measurement and Hemodynamic Analysis
    “... was an independent risk factor for PAA rupture (OR = 6.45, 95% CI 1.37–30.32, P = 0.018).Conclusion: This preliminary...”
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  7. 2527
    Dynamic analysis of stochastic transcription cycles.
    “... cells. However, the timing of the cycles was independent and out-of-phase. For the first time, we have...”
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  8. 2528
    Multi-study integration of brain cancer transcriptomes reveals organ-level molecular signatures.
    “.... For this reason, we restricted ourselves to studying only cases where we had at least two independent studies...”
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  9. 2529
    Graph-based analysis of the metabolic exchanges between two co-resident intracellular symbionts, Baumannia cicadellinicola and Sulcia muelleri, with their insect host, Homalodisca coagulata.
    “... results show that the carbon metabolism of S. muelleri may be completely independent of the metabolic...”
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  10. 2530
    Reliable B cell epitope predictions: impacts of method development and improved benchmarking.
    “... displayed improved performance both in cross-validation and in independent evaluations. Using DiscoTope-2.0...”
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  11. 2531
    Tim-3 expression in cervical cancer promotes tumor metastasis.
    “... was an independent factor for predicting the prognosis of cervical cancer. Significantly, down-regulating...”
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  12. 2532
    An ensemble method for predicting subnuclear localizations from primary protein structures.
    “... is evaluated on four datasets: Lei dataset, multi-localization dataset, SNL9 dataset and a new independent...”
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  13. 2533
    Differences in sepsis treatment and outcomes between public and private hospitals in Brazil: a multicenter observational study.
    “... that age, disease severity at baseline and being treated at a public hospital were independent risk factors...”
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  14. 2534
    MiR-SNPs as markers of toxicity and clinical outcome in Hodgkin lymphoma patients.
    “... emerged as independent factors in the multivariate analysis. The XPO5 AA and CC genotypes were also...”
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  15. 2535
    Postoperative neutrophil-to-lymphocyte ratio change predicts survival of patients with small hepatocellular carcinoma undergoing radiofrequency ablation.
    “..., was an independent prognostic factor for both OS (P<0.001, HR = 2.39, 95%CI 1.53-3.72) and RFS (P = 0.003, HR = 1.69...”
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  16. 2536
    MicroRNA-195 inhibits the proliferation of human glioma cells by directly targeting cyclin D1 and cyclin E1.
    “... phase cells. Overexpression of miR-195 dramatically reduced the anchorage-independent growth ability...”
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  17. 2537
    Association of new loci identified in European genome-wide association studies with susceptibility to type 2 diabetes in the Japanese.
    “... study using 3 independent Japanese case-control studies.<h4>Methodology/principal findings</h4>We...”
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  18. 2538
    NK-like T cells and plasma cytokines, but not anti-viral serology, define immune fingerprints of resilience and mild disability in exceptional aging.
    “...D. In logistic regression models, unimpaired phenotype was predicted independently by IL-5 and by CD...”
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  19. 2539
    Acute overactive endocannabinoid signaling induces glucose intolerance, hepatic steatosis, and novel cannabinoid receptor 1 responsive genes.
    “... of endogenously produced endocannabinoids to cause hepatic lipid accumulation and insulin resistance, independent...”
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  20. 2540
    Quantitative mass spectrometry analysis using PAcIFIC for the identification of plasma diagnostic biomarkers for abdominal aortic aneurysm.
    “... control patients were depleted of the most abundant proteins and compared using a data-independent shotgun...”
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