Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2

por Yanbo Fan, Brooke N. Wolford, Haocheng Lu, Wenying Liang, Jinjian Sun, Wei Zhou, Oren Rom, Anubha Mahajan, Ida Surakka, Sarah E. Graham, Zhipeng Liu, Hyunbae Kim, Shweta Ramdas, Lars G. Fritsche, Jonas B. Nielsen, Maiken Elvestad Gabrielsen, Kristian Hveem, Dongshan Yang, Jun Song, Minerva T. Garcia-Barrio, Jifeng Zhang, Wanqing Liu, Kezhong Zhang, Cristen J. Willer, Y. Eugene Chen
Publicado 2021

Blockchain applications in health care for COVID-19 and beyond: a systematic review

por Wei Yan Ng, FRCOphth, Tien-En Tan, FRCOphth, Prasanth V H Movva, BEng, Andrew Hao Sen Fang, MBBS, Khung-Keong Yeo, ABIM, Dean Ho, ProfPhD, Fuji Shyy San Foo, MBA, Zhe Xiao, PhD, Kai Sun, PhD, Tien Yin Wong, ProfPhD, Alex Tiong-Heng Sia, FAMS, Daniel Shu Wei Ting, PhD
Publicado 2021

AQP9 Is a Prognostic Factor for Kidney Cancer and a Promising Indicator for M2 TAM Polarization and CD8+ T-Cell Recruitment

por Jibo Jing, Jibo Jing, Jibo Jing, Jin Sun, Yuqing Wu, Yuqing Wu, Yuqing Wu, Nieke Zhang, Nieke Zhang, Nieke Zhang, Chunhui Liu, Chunhui Liu, Chunhui Liu, Saisai Chen, Saisai Chen, Saisai Chen, Wenchao Li, Wenchao Li, Wenchao Li, Cheng Hong, Cheng Hong, Cheng Hong, Bin Xu, Bin Xu, Bin Xu, Ming Chen, Ming Chen, Ming Chen
Publicado 2021

Culture Enrichment Combined With Long-Read Sequencing Facilitates Genomic Understanding of Hadal Sediment Microbes

por Huan Wang, Huan Wang, Huan Wang, Meng Wang, Meng Wang, Meng Wang, Shen Fan, Shen Fan, Shen Fan, Jie Lu, Jie Lu, Jie Lu, Yi Lan, Yi Lan, Menggong Li, Jiangyan Li, Rulong Liu, Jin Sun, Jiasong Fang, Pei-Yuan Qian, Pei-Yuan Qian, Yu-Zhong Zhang, Yu-Zhong Zhang, Yu-Zhong Zhang, Weipeng Zhang, Weipeng Zhang
Publicado 2021

Safety and Immunogenicity of a Newcastle Disease Virus Vector-Based SARS-CoV-2 Vaccine Candidate, AVX/COVID-12-HEXAPRO (Patria), in Pigs

por Jesús Horacio Lara-Puente, Juan Manuel Carreño, Weina Sun, Alejandro Suárez-Martínez, Luis Ramírez-Martínez, Francisco Quezada-Monroy, Georgina Paz-De la Rosa, Rosalía Vigueras-Moreno, Gagandeep Singh, Oscar Rojas-Martínez, Héctor Elías Chagoya-Cortés, David Sarfati-Mizrahi, Ernesto Soto-Priante, Constantino López-Macías, Florian Krammer, Felipa Castro-Peralta, Peter Palese, Adolfo García-Sastre, Bernardo Lozano-Dubernard
Publicado 2021

A Low-Producing Haplotype of Interleukin-6 Disrupting CTCF Binding Is Protective against Severe COVID-19

por Tao Chen, Yu-Xin Lin, Yan Zha, Ying Sun, Jinxiu Tian, Zhiying Yang, Shan-Wen Lin, Fuxun Yu, Zi-Sheng Chen, Bo-Hua Kuang, Jin-Ju Lei, Ying-jie Nie, Yonghao Xu, Dong-Bo Tian, Ying-Zi Li, Bin Yang, Qiang Xu, Li Yang, Nanshan Zhong, Meizhen Zheng, Yimin Li, Jincun Zhao, Xiang-Yan Zhang, Lin Feng
Publicado 2021

Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids

por Ann-Na Cho, Yoonhee Jin, Yeonjoo An, Jin Kim, Yi Sun Choi, Jung Seung Lee, Junghoon Kim, Won-Young Choi, Dong-Jun Koo, Weonjin Yu, Gyeong-Eon Chang, Dong-Yoon Kim, Sung-Hyun Jo, Jihun Kim, Sung-Yon Kim, Yun-Gon Kim, Ju Young Kim, Nakwon Choi, Eunji Cheong, Young-Joon Kim, Hyunsoo Shawn Je, Hoon-Chul Kang, Seung-Woo Cho
Publicado 2021

CpG-adjuvanted stable prefusion SARS-CoV-2 spike protein protected hamsters from SARS-CoV-2 challenge

por Chia-En Lien, Yi-Jiun Lin, Charles Chen, Wei-Cheng Lian, Tsun-Yung Kuo, John D. Campbell, Paula Traquina, Meei-Yun Lin, Luke Tzu-Chi Liu, Ya-Shan Chuang, Hui-Ying Ko, Chun-Che Liao, Yen-Hui Chen, Jia-Tsrong Jan, Hsiu-Hua Ma, Cheng-Pu Sun, Yin-Shiou Lin, Ping-Yi Wu, Yu-Chiuan Wang, Mi-Hua Tao, Yi-Ling Lin
Publicado 2021

Integrated genomics point to immune vulnerabilities in pleural mesothelioma

por Anca Nastase, Amit Mandal, Shir Kiong Lu, Hima Anbunathan, Deborah Morris-Rosendahl, Yu Zhi Zhang, Xiao-Ming Sun, Spyridon Gennatas, Robert C. Rintoul, Matthew Edwards, Alex Bowman, Tatyana Chernova, Tim Benepal, Eric Lim, Anthony Newman Taylor, Andrew G. Nicholson, Sanjay Popat, Anne E. Willis, Marion MacFarlane, Mark Lathrop, Anne M. Bowcock, Miriam F. Moffatt, William O. C. M. Cookson
Publicado 2021

YAP/TAZ direct commitment and maturation of lymph node fibroblastic reticular cells

por Sung Yong Choi, Hosung Bae, Sun-Hye Jeong, Intae Park, Hyunsoo Cho, Seon Pyo Hong, Da-Hye Lee, Choong-kun Lee, Jin-Sung Park, Sang Heon Suh, Jeongwoon Choi, Myung Jin Yang, Jeon Yeob Jang, Lucas Onder, Jeong Hwan Moon, Han-Sin Jeong, Ralf H. Adams, Jin-Man Kim, Burkhard Ludewig, Joo-Hye Song, Dae-Sik Lim, Gou Young Koh
Publicado 2020

Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses

por Christian K. Holm, Stine H. Rahbek, Hans Henrik Gad, Rasmus O. Bak, Martin R. Jakobsen, Zhaozaho Jiang, Anne Louise Hansen, Simon K. Jensen, Chenglong Sun, Martin K. Thomsen, Anders Laustsen, Camilla G. Nielsen, Kasper Severinsen, Yingluo Xiong, Dara L. Burdette, Veit Hornung, Robert Jan Lebbink, Mogens Duch, Katherine A. Fitzgerald, Shervin Bahrami, Jakob Giehm Mikkelsen, Rune Hartmann, Søren R. Paludan
Publicado 2016

Recurrent GNAQ mutation encoding T96S in natural killer/T cell lymphoma

por Zhaoming Li, Xudong Zhang, Weili Xue, Yanjie Zhang, Chaoping Li, Yue Song, Mei Mei, Lisha Lu, Yingjun Wang, Zhiyuan Zhou, Mengyuan Jin, Yangyang Bian, Lei Zhang, Xinhua Wang, Ling Li, Xin Li, Xiaorui Fu, Zhenchang Sun, Jingjing Wu, Feifei Nan, Yu Chang, Jiaqin Yan, Hui Yu, Xiaoyan Feng, Guannan Wang, Dandan Zhang, Xuefei Fu, Yuan Zhang, Ken H. Young, Wencai Li, Mingzhi Zhang
Publicado 2019

Loss-of-function mutations in QRICH2 cause male infertility with multiple morphological abnormalities of the sperm flagella

por Ying Shen, Feng Zhang, Fuping Li, Xiaohui Jiang, Yihong Yang, Xiaoliang Li, Weiyu Li, Xiang Wang, Juan Cheng, Mohan Liu, Xueguang Zhang, Guiping Yuan, Xue Pei, Kailai Cai, Fengyun Hu, Jianfeng Sun, Lanzhen Yan, Li Tang, Chuan Jiang, Wenling Tu, Jinyan Xu, Haojuan Wu, Weiqi Kong, Shuying Li, Ke Wang, Kai Sheng, Xudong Zhao, Huanxun Yue, Xiaoyu Yang, Wenming Xu
Publicado 2019

Modulation of brain cation-Cl− cotransport via the SPAK kinase inhibitor ZT-1a

por Jinwei Zhang, Mohammad Iqbal H. Bhuiyan, Ting Zhang, Jason K. Karimy, Zhijuan Wu, Victoria M. Fiesler, Jingfang Zhang, Huachen Huang, Md Nabiul Hasan, Anna E. Skrzypiec, Mariusz Mucha, Daniel Duran, Wei Huang, Robert Pawlak, Lesley M. Foley, T. Kevin Hitchens, Margaret B. Minnigh, Samuel M. Poloyac, Seth L. Alper, Bradley J. Molyneaux, Andrew J. Trevelyan, Kristopher T. Kahle, Dandan Sun, Xianming Deng
Publicado 2020

RhoGAP domain-containing fusions and PPAPDC1A fusions are recurrent and prognostic in diffuse gastric cancer

por Hanna Yang, Dongwan Hong, Soo Young Cho, Young Soo Park, Woo Ri Ko, Ju Hee Kim, Hoon Hur, Jongkeun Lee, Su-Jin Kim, Sun Young Kwon, Jae-Hyuk Lee, Do Youn Park, Kyu Sang Song, Heekyung Chang, Min-Hee Ryu, Kye Soo Cho, Jeong Won Kang, Myeong-Cherl Kook, Nina Thiessen, An He, Andy Mungall, Sang-Uk Han, Hark Kyun Kim
Publicado 2018

Wars2 is a determinant of angiogenesis

por Mao Wang, Patrick Sips, Ester Khin, Maxime Rotival, Ximing Sun, Rizwan Ahmed, Anissa Anindya Widjaja, Sebastian Schafer, Permeen Yusoff, Pervinder Kaur Choksi, Nicole Shi Jie Ko, Manvendra K. Singh, David Epstein, Yuguang Guan, Josef Houštěk, Tomas Mracek, Hana Nuskova, Brittney Mikell, Jessie Tan, Francesco Pesce, Frantisek Kolar, Leonardo Bottolo, Massimiliano Mancini, Norbert Hubner, Michal Pravenec, Enrico Petretto, Calum MacRae, Stuart A Cook
Publicado 2016

Metagenome-wide association of gut microbiome features for schizophrenia

por Feng Zhu, Yanmei Ju, Wei Wang, Qi Wang, Ruijin Guo, Qingyan Ma, Qiang Sun, Yajuan Fan, Yuying Xie, Zai Yang, Zhuye Jie, Binbin Zhao, Liang Xiao, Lin Yang, Tao Zhang, Junqin Feng, Liyang Guo, Xiaoyan He, Yunchun Chen, Ce Chen, Chengge Gao, Xun Xu, Huanming Yang, Jian Wang, Yonghui Dang, Lise Madsen, Susanne Brix, Karsten Kristiansen, Huijue Jia, Xiancang Ma
Publicado 2020

Display of the human mucinome with defined O-glycans by gene engineered cells

por Rebecca Nason, Christian Büll, Andriana Konstantinidi, Lingbo Sun, Zilu Ye, Adnan Halim, Wenjuan Du, Daniel M. Sørensen, Fabien Durbesson, Sanae Furukawa, Ulla Mandel, Hiren J. Joshi, Leo Alexander Dworkin, Lars Hansen, Leonor David, Tina M. Iverson, Barbara A. Bensing, Paul M. Sullam, Ajit Varki, Erik de Vries, Cornelis A. M. de Haan, Renaud Vincentelli, Bernard Henrissat, Sergey Y. Vakhrushev, Henrik Clausen, Yoshiki Narimatsu
Publicado 2021

Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro

por Hsiang-Chi Huang, Yun-Ju Lai, Chun-Che Liao, Wang-Feng Yang, Ke-Bin Huang, I-Jung Lee, Wen-Cheng Chou, Shih-Han Wang, Ling-Hui Wang, Jung-Mao Hsu, Cheng-Pu Sun, Chun-Tse Kuo, Jyun Wang, Tzu-Chun Hsiao, Po-Jiun Yang, Te-An Lee, Wilson Huang, Fu-An Li, Chen-Yang Shen, Yi-Ling Lin, Mi-Hua Tao, Chia-Wei Li
Publicado 2021

Safety of endovascular therapy for symptomatic intracranial artery stenosis: a national prospective registry

por Yongli Li, Yang Zhang, Osama O Zaidat, Liqun Jiao, Wei Wu, Bo Hong, Hua Yang, Qiong Cheng, Adam Andrew Dmytriw, Jie Lu, Kun Yang, Xueli Cai, Tianxiao Li, Yiling Cai, Huaizhang Shi, Zhenwei Zhao, Xiaoxin Bai, Zuoquan Chen, Yabing Wang, Jun Zhao, Qinjian Sun, Jieqing Wan, Liyong Zhang, Yujie Huang, Jianfeng Chu, Pengfei Wang, Qi Luo, Baijing Dong, Weiwen He, Maimai Ti