HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons

por Sarah Kishinevsky, Tai Wang, Anna Rodina, Sun Young Chung, Chao Xu, John Philip, Tony Taldone, Suhasini Joshi, Mary L. Alpaugh, Alexander Bolaender, Simon Gutbier, Davinder Sandhu, Faranak Fattahi, Bastian Zimmer, Smit K. Shah, Elizabeth Chang, Carmen Inda, John Koren, Nathalie G. Saurat, Marcel Leist, Steven S. Gross, Venkatraman E. Seshan, Christine Klein, Mark J. Tomishima, Hediye Erdjument-Bromage, Thomas A. Neubert, Ronald C. Henrickson, Gabriela Chiosis, Lorenz Studer
Publicado 2018

Genome-enabled discovery of anthraquinone biosynthesis in Senna tora

por Sang-Ho Kang, Ramesh Prasad Pandey, Chang-Muk Lee, Joon-Soo Sim, Jin-Tae Jeong, Beom-Soon Choi, Myunghee Jung, Daniel Ginzburg, Kangmei Zhao, So Youn Won, Tae-Jin Oh, Yeisoo Yu, Nam-Hoon Kim, Ok Ran Lee, Tae-Ho Lee, Puspalata Bashyal, Tae-Su Kim, Woo-Haeng Lee, Charles Hawkins, Chang-Kug Kim, Jung Sun Kim, Byoung Ohg Ahn, Seung Yon Rhee, Jae Kyung Sohng
Publicado 2020

Resequencing 545 ginkgo genomes across the world reveals the evolutionary history of the living fossil

por Yun-Peng Zhao, Guangyi Fan, Ping-Ping Yin, Shuai Sun, Ning Li, Xiaoning Hong, Gang Hu, He Zhang, Fu-Min Zhang, Jing-Dan Han, Ya-Jun Hao, Qiwu Xu, Xianwei Yang, Wenjie Xia, Wenbin Chen, Han-Yang Lin, Rui Zhang, Jiang Chen, Xiao-Ming Zheng, Simon Ming-Yuen Lee, Joongku Lee, Koichi Uehara, Jian Wang, Huanming Yang, Cheng-Xin Fu, Xin Liu, Xun Xu, Song Ge
Publicado 2019

Vasculogenic mimicry in small cell lung cancer

por Stuart C. Williamson, Robert L. Metcalf, Francesca Trapani, Sumitra Mohan, Jenny Antonello, Benjamin Abbott, Hui Sun Leong, Christopher P. E. Chester, Nicole Simms, Radoslaw Polanski, Daisuke Nonaka, Lynsey Priest, Alberto Fusi, Fredrika Carlsson, Anders Carlsson, Mary J. C. Hendrix, Richard E. B. Seftor, Elisabeth A. Seftor, Dominic G. Rothwell, Andrew Hughes, James Hicks, Crispin Miller, Peter Kuhn, Ged Brady, Kathryn L. Simpson, Fiona H. Blackhall, Caroline Dive
Publicado 2016

Purine metabolism regulates DNA repair and therapy resistance in glioblastoma

por Weihua Zhou, Yangyang Yao, Andrew J. Scott, Kari Wilder-Romans, Joseph J. Dresser, Christian K. Werner, Hanshi Sun, Drew Pratt, Peter Sajjakulnukit, Shuang G. Zhao, Mary Davis, Barbara S. Nelson, Christopher J. Halbrook, Li Zhang, Francesco Gatto, Yoshie Umemura, Angela K. Walker, Maureen Kachman, Jann N. Sarkaria, Jianping Xiong, Meredith A. Morgan, Alnawaz Rehemtualla, Maria G. Castro, Pedro Lowenstein, Sriram Chandrasekaran, Theodore S. Lawrence, Costas A. Lyssiotis, Daniel R. Wahl
Publicado 2020

The pathogenesis of mesothelioma is driven by a dysregulated translatome

por Stefano Grosso, Alberto Marini, Katarina Gyuraszova, Johan Vande Voorde, Aristeidis Sfakianos, Gavin D. Garland, Angela Rubio Tenor, Ryan Mordue, Tanya Chernova, Nobu Morone, Marco Sereno, Claire P. Smith, Leah Officer, Pooyeh Farahmand, Claire Rooney, David Sumpton, Madhumita Das, Ana Teodósio, Catherine Ficken, Maria Guerra Martin, Ruth V. Spriggs, Xiao-Ming Sun, Martin Bushell, Owen J. Sansom, Daniel Murphy, Marion MacFarlane, John P. C. Le Quesne, Anne E. Willis
Publicado 2021

Asian Pacific Society of Cardiology Consensus Recommendations on the Use of MitraClip for Mitral Regurgitation

por Khung Keong Yeo, Jack Wei Chieh Tan, David WM Muller, Darren L Walters, JoAnn Lindenfeld, Michael Kang Yin Lee, Angus Shing Fung Chui, Sai Satish, Teguh Santoso, Shunsuke Kubo, John Chan Kok Meng, Kenny YK Sin, See Hooi Ewe, David Sim, Edgar Tay, Krissada Meemook, Shih-Hsien Sung, Quang Ngoc Nguyen, Xiangbin Pan, Makoto Amaki, Masaki Izumo, Kentaro Hayashida, Jung Sun Kim, Do-Yoon Kang, Gregg Stone, Takashi Matsumoto
Publicado 2021

A bispecific antibody targeting sclerostin and DKK-1 promotes bone mass accrual and fracture repair

por Monica Florio, Kannan Gunasekaran, Marina Stolina, Xiaodong Li, Ling Liu, Barbara Tipton, Hossein Salimi-Moosavi, Franklin J. Asuncion, Chaoyang Li, Banghua Sun, Hong Lin Tan, Li Zhang, Chun-Ya Han, Ryan Case, Amy N. Duguay, Mario Grisanti, Jennitte Stevens, James K. Pretorius, Efrain Pacheco, Heidi Jones, Qing Chen, Brian D. Soriano, Jie Wen, Brenda Heron, Frederick W. Jacobsen, Emil Brisan, William G. Richards, Hua Zhu Ke, Michael S. Ominsky
Publicado 2016

Disrupting biological sensors of force promotes tissue regeneration in large organisms

por Kellen Chen, Sun Hyung Kwon, Dominic Henn, Britta A. Kuehlmann, Ruth Tevlin, Clark A. Bonham, Michelle Griffin, Artem A. Trotsyuk, Mimi R. Borrelli, Chikage Noishiki, Jagannath Padmanabhan, Janos A. Barrera, Zeshaan N. Maan, Teruyuki Dohi, Chyna J. Mays, Autumn H. Greco, Dharshan Sivaraj, John Q. Lin, Tobias Fehlmann, Alana M. Mermin-Bunnell, Smiti Mittal, Michael S. Hu, Alsu I. Zamaleeva, Andreas Keller, Jayakumar Rajadas, Michael T. Longaker, Michael Januszyk, Geoffrey C. Gurtner
Publicado 2021

Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent

por Anren Song, Yujin Zhang, Leng Han, Gennady G. Yegutkin, Hong Liu, Kaiqi Sun, Angelo D’Alessandro, Jessica Li, Harry Karmouty-Quintana, Takayuki Iriyama, Tingting Weng, Shushan Zhao, Wei Wang, Hongyu Wu, Travis Nemkov, Andrew W. Subudhi, Sonja Jameson-Van Houten, Colleen G. Julian, Andrew T. Lovering, Kirk C. Hansen, Hong Zhang, Mikhail Bogdanov, William Dowhan, Jianping Jin, Rodney E. Kellems, Holger K. Eltzschig, Michael Blackburn, Robert C. Roach, Yang Xia
Publicado 2017

Structure mapping of dengue and Zika viruses reveals functional long-range interactions

por Roland G. Huber, Xin Ni Lim, Wy Ching Ng, Adelene Y. L. Sim, Hui Xian Poh, Yang Shen, Su Ying Lim, Karin B. Sundstrom, Xuyang Sun, Jong Ghut Aw, Horng Khit Too, Peng Hee Boey, Andreas Wilm, Tanu Chawla, Milly M. Choy, Lu Jiang, Paola Florez de Sessions, Xian Jun Loh, Sylvie Alonso, Martin Hibberd, Niranjan Nagarajan, Eng Eong Ooi, Peter J. Bond, October M. Sessions, Yue Wan
Publicado 2019

In-orbit operation of an atomic clock based on laser-cooled 87Rb atoms

por Liang Liu, De-Sheng Lü, Wei-Biao Chen, Tang Li, Qiu-Zhi Qu, Bin Wang, Lin Li, Wei Ren, Zuo-Ren Dong, Jian-Bo Zhao, Wen-Bing Xia, Xin Zhao, Jing-Wei Ji, Mei-Feng Ye, Yan-Guang Sun, Yuan-Yuan Yao, Dan Song, Zhao-Gang Liang, Shan-Jiang Hu, Dun-He Yu, Xia Hou, Wei Shi, Hua-Guo Zang, Jing-Feng Xiang, Xiang-Kai Peng, Yu-Zhu Wang
Publicado 2018

Efficacy and safety of a novel anti‐HER2 therapeutic antibody RC48 in patients with HER2‐overexpressing, locally advanced or metastatic gastric or gastroesophageal junction cancer:...

por Zhi Peng, Tianshu Liu, Jia Wei, Airong Wang, Yifu He, Liuzhong Yang, Xizhi Zhang, Nanfeng Fan, Suxia Luo, Zhen Li, Kangsheng Gu, Jianwei Lu, Jianming Xu, Qingxia Fan, Ruihua Xu, Liangming Zhang, Enxiao Li, Yuping Sun, Guohua Yu, Chunmei Bai, Yong Liu, Jiangzheng Zeng, Jieer Ying, Xinjun Liang, Nong Xu, Chao Gao, Yongqian Shu, Dong Ma, Guanghai Dai, Shengmian Li, Ting Deng, Yuehong Cui, Jianmin Fang, Yi Ba, Lin Shen
Publicado 2021

Patient‐Derived Organoids Can Guide Personalized‐Therapies for Patients with Advanced Breast Cancer

por Ping Chen, Xu Zhang, Renbo Ding, Linglin Yang, Xueying Lyu, Jianming Zeng, Josh Haipeng Lei, Lijian Wang, Jiong Bi, Nan Shao, Ditian Shu, Bin Wu, Jingbo Wu, Zhihui Yang, Haiyan Wang, Biqiong Wang, Kang Xiong, Yun Lu, Shaozhi Fu, Tak Kan Choi, Ng Wai Lon, Aiping Zhang, Dongyang Tang, Yingyao Quan, Ya Meng, Kai Miao, Heng Sun, Ming Zhao, Jiaolin Bao, Lei Zhang, Xiaoling Xu, Yanxia Shi, Ying Lin, Chuxia Deng
Publicado 2021

Discovery and Genomic Characterization of a 382-Nucleotide Deletion in ORF7b and ORF8 during the Early Evolution of SARS-CoV-2

por Yvonne C. F. Su, Danielle E. Anderson, Barnaby E. Young, Martin Linster, Feng Zhu, Jayanthi Jayakumar, Yan Zhuang, Shirin Kalimuddin, Jenny G. H. Low, Chee Wah Tan, Wan Ni Chia, Tze Minn Mak, Sophie Octavia, Jean-Marc Chavatte, Raphael T. C. Lee, Surinder Pada, Seow Yen Tan, Louisa Sun, Gabriel Z. Yan, Sebastian Maurer-Stroh, Ian H. Mendenhall, Yee-Sin Leo, David Chien Lye, Lin-Fa Wang, Gavin J. D. Smith
Publicado 2020

WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling

por Huimei Chen, Aida Moreno-Moral, Francesco Pesce, Nithya Devapragash, Massimiliano Mancini, Ee Ling Heng, Maxime Rotival, Prashant K. Srivastava, Nathan Harmston, Kirill Shkura, Owen J. L. Rackham, Wei-Ping Yu, Xi-Ming Sun, Nicole Gui Zhen Tee, Elisabeth Li Sa Tan, Paul J. R. Barton, Leanne E. Felkin, Enrique Lara-Pezzi, Gianni Angelini, Cristina Beltrami, Michal Pravenec, Sebastian Schafer, Leonardo Bottolo, Norbert Hubner, Costanza Emanueli, Stuart A. Cook, Enrico Petretto
Publicado 2019

Tumour-initiating cell-specific miR-1246 and miR-1290 expression converge to promote non-small cell lung cancer progression

por Wen Cai Zhang, Tan Min Chin, Henry Yang, Min En Nga, Declan Patrick Lunny, Edwin Kok Hao Lim, Li Li Sun, Yin Huei Pang, Yi Ning Leow, Shanneen Rossellini Y Malusay, Priscilla Xin Hui Lim, Jeravan Zili Lee, Benedict Jian Wei Tan, Ng Shyh-Chang, Elaine Hsuen Lim, Wan Teck Lim, Daniel Shao Weng Tan, Eng Huat Tan, Bee Choo Tai, Ross Andrew Soo, Wai Leong Tam, Bing Lim
Publicado 2016

Perovskite neural trees

por Hai-Tian Zhang, Tae Joon Park, Ivan A. Zaluzhnyy, Qi Wang, Shakti Nagnath Wadekar, Sukriti Manna, Robert Andrawis, Peter O. Sprau, Yifei Sun, Zhen Zhang, Chengzi Huang, Hua Zhou, Zhan Zhang, Badri Narayanan, Gopalakrishnan Srinivasan, Nelson Hua, Evgeny Nazaretski, Xiaojing Huang, Hanfei Yan, Mingyuan Ge, Yong S. Chu, Mathew J. Cherukara, Martin V. Holt, Muthu Krishnamurthy, Oleg G. Shpyrko, Subramanian K.R.S. Sankaranarayanan, Alex Frano, Kaushik Roy, Shriram Ramanathan
Publicado 2020

Co-activation of super-enhancer-driven CCAT1 by TP63 and SOX2 promotes squamous cancer progression

por Yuan Jiang, Yan-Yi Jiang, Jian-Jun Xie, Anand Mayakonda, Masaharu Hazawa, Li Chen, Jin-Fen Xiao, Chun-Quan Li, Mo-Li Huang, Ling-Wen Ding, Qiao-Yang Sun, Liang Xu, Deepika Kanojia, Maya Jeitany, Jian-Wen Deng, Lian-Di Liao, Harmik J. Soukiasian, Benjamin P. Berman, Jia-Jie Hao, Li-Yan Xu, En-Min Li, Ming-Rong Wang, Xin-Gang Bi, De-Chen Lin, H. Phillip Koeffler
Publicado 2018

Penaeid shrimp genome provides insights into benthic adaptation and frequent molting

por Xiaojun Zhang, Jianbo Yuan, Yamin Sun, Shihao Li, Yi Gao, Yang Yu, Chengzhang Liu, Quanchao Wang, Xinjia Lv, Xiaoxi Zhang, Ka Yan Ma, Xiaobo Wang, Wenchao Lin, Long Wang, Xueli Zhu, Chengsong Zhang, Jiquan Zhang, Songjun Jin, Kuijie Yu, Jie Kong, Peng Xu, Jack Chen, Hongbin Zhang, Patrick Sorgeloos, Amir Sagi, Acacia Alcivar-Warren, Zhanjiang Liu, Lei Wang, Jue Ruan, Ka Hou Chu, Bin Liu, Fuhua Li, Jianhai Xiang
Publicado 2019