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  1. 981
    The cooperative binding of TDP-43 to GU-rich RNA repeats antagonizes TDP-43 aggregation
    “... neurodegenerative diseases, ALS and FTLD. While the self-assembly of TDP-43 by its structured N-terminal...”
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  2. 982
    PTENα functions as an immune suppressor and promotes immune resistance in PTEN-mutant cancer
    “...PTENα is an N-terminally extended isoform of PTEN, a gene frequently mutated in human cancers. Here...”
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  3. 983
    IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expression
    “... with the C-terminal fragment of NOTCH1 (NICD) to activate cell proliferation and an inflammatory response....”
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  4. 984
    The conserved NxNNWHW motif in Aha-type co-chaperones modulates the kinetics of Hsp90 ATPase stimulation
    “... and activation of many client proteins. Here authors show that a N-terminal motif in Aha-type co-chaperones...”
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  5. 985
    PTENβ is an alternatively translated isoform of PTEN that regulates rDNA transcription
    “... the authors identify an N-terminal extended isoform of PTEN, termed PTENβ that negatively regulates ribosomal...”
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  6. 986
    The mitotic kinesin-14 KlpA contains a context-dependent directionality switch
    “... the authors show that KlpA, a fungal kinesin-14 orthologue, relies on its N-terminal nonmotor microtubule...”
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  7. 987
    Copper-catalyzed enantioselective Sonogashira-type oxidative cross-coupling of unactivated C(sp 3)−H bonds with alkynes
    “...Enantioselective oxidative cross-coupling of unactivated C(sp 3)−H bonds and terminal alkynes...”
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  8. 988
    Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development
    “... are unclear. Here, Lampe et al. show that the blood-meal induced miR-276 balances the termination...”
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  9. 989
    The H2A.Z histone variant integrates Wnt signaling in intestinal epithelial homeostasis
    “..., by preventing terminal differentiation of intestinal progenitors....”
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  10. 990
    The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels
    “... al. show that the N-terminal helix of MscL dynamically couples membrane tension to channel gating...”
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  11. 991
    Evidence that phytochrome functions as a protein kinase in plant light signalling
    “... that phytochrome phosphorylates target proteins via kinase activity in the N-terminal core domain....”
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  12. 992
    Oxygen radical character in group 11 oxygen fluorides
    “...While transition metal complexes bearing terminal oxido ligands are common, those of group 11...”
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  13. 993
    CDK1 dependent phosphorylation of hTERT contributes to cancer progression
    “... dependent RNA polymerase activity but not for reverse transcriptase and terminal transferase activities....”
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  14. 994
    Alkyl halides as both hydride and alkyl sources in catalytic regioselective reductive olefin hydroalkylation
    “...Methods that regioselectively install a functionalized alkyl unit at the 2-position of a terminal...”
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  15. 995
    Single-site glycine-specific labeling of proteins
    “... developed a method in which they use an aldol-type reaction to modify proteins at N-terminal glycine...”
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  16. 996
    Activation mechanism of a small prototypic Rec-GGDEF diguanylate cyclase
    “... changes and the activation mechanism likely shared by many DGCs with N-terminal coiled-coil linkers....”
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  17. 997
    PKC-phosphorylation of Liprin-α3 triggers phase separation and controls presynaptic active zone structure
    “...Liquid–liquid phase separation may be a mechanism for organizing the presynaptic nerve terminal...”
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  18. 998
    Subglacial discharge controls seasonal variations in the thermal structure of a glacial lake in Patagonia
    “... atmospheric warming, glacier front melting and calving for freshwater-terminating glaciers....”
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  19. 999
    Parkinson’s disease associated mutation E46K of α-synuclein triggers the formation of a distinct fibril structure
    “... the cryo-EM structure of N-terminally acetylated E46K α-synuclein fibrils and find that it is distinct from...”
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  20. 1000
    Dopaminergic dynamics underlying sex-specific cocaine reward
    “... in DAT function expressed in terminals in the NAc. These differences underlie enhanced cocaine reward...”
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