Radicicol-Mediated Inhibition of Topoisomerase VIB-VIA Activity of the Human Malaria Parasite <named-content content-type="genus-species">Plasmodium falciparum</named-content>

por Sureshkumar Chalapareddy, Swati Chakrabarty, Mrinal Kanti Bhattacharyya, Sunanda Bhattacharyya
Publicado 2016

INDUCTION OF C-MYC G-QUADRUPLEX DNA AND CYTOTOXICITY OF A CALIX[]ARENE-CONTAINING BINUCLEAR RUTHENIUM(II) COMPLEX

por Mi,Ya-Xuan, Wang,Shuang, Yan,Shuang-Mei, Cui,Yue, Wang,Ming-He, Zheng,Ze-Bao, Zhao,Xiao-Long
Publicado 2019

New molecular biologist perspective and insight: DNA topoisomerases production by recombinant DNA technology for medical laboratory application and pharmaceutical industry

por Chan,Mooi Kwai, Fadzil,Nur Adila, Chew,Ai Lan, Khoo,Boon Yin
Publicado 2013

Novel 1,2,4-oxadiazole/pyrrolidine hybrids as DNA gyrase and topoisomerase IV inhibitors with potential antibacterial activity

por Firas Obaid Arhema Frejat, Yaquan Cao, Hongjin Zhai, Salah A. Abdel-Aziz, Hesham A.M. Gomaa, Bahaa G.M. Youssif, Chunli Wu
Publicado 2022

Pharmacokinetics and safety of DTS-108, a human oligopeptide bound to SN-38 with an esterase-sensitive cross-linker in patients with advanced malignancies: a Phase I study

por Coriat R, Faivre SJ, Mir O, Dreyer C, Ropert S, Bouattour M, Desjardins R, Goldwasser F, Raymond E
Publicado 2016

The Antileukemic Effect of Xestoquinone, A Marine-Derived Polycyclic Quinone-Type Metabolite, Is Mediated through ROS-Induced Inhibition of HSP-90

por Kuan-Chih Wang, Mei-Chin Lu, Kai-Cheng Hsu, Mohamed El-Shazly, Shou-Ping Shih, Ssu-Ting Lien, Fu-Wen Kuo, Shyh-Chyun Yang, Chun-Lin Chen, Yu-Chen S. H. Yang
Publicado 2021

Topoisomerase 1 Inhibition Promotes Cyclic GMP-AMP Synthase-Dependent Antiviral Responses

por Geneviève Pépin, Charlotte Nejad, Jonathan Ferrand, Belinda J. Thomas, H. James Stunden, Elaine Sanij, Chwan-Hong Foo, Cameron R. Stewart, Jason E. Cain, Philip G. Bardin, Bryan R. G. Williams, Michael P. Gantier
Publicado 2017

Topoisomerase-Mediated DNA Damage in Neurological Disorders

por Morgan Crewe, Ram Madabhushi
Publicado 2021

Competitive binding of MatP and topoisomerase IV to the MukB hinge domain

por Gemma LM Fisher, Jani R Bolla, Karthik V Rajasekar, Jarno Mäkelä, Rachel Baker, Man Zhou, Josh P Prince, Mathew Stracy, Carol V Robinson, Lidia K Arciszewska, David J Sherratt
Publicado 2021

Estradiol increases risk of topoisomerase IIβ-mediated DNA strand breaks to initiate Xp11.2 translocation renal cell carcinoma

por Qiancheng Shi, Ning Liu, Lei Yang, Yi Chen, Yanwen Lu, Hongqian Guo, Xiaodong Han, Dongmei Li, Weidong Gan
Publicado 2021

Synthesis, Characterization, Biomedical Application, Molecular Dynamic Simulation and Molecular Docking of Schiff Base Complex of Cu(II) Supported on Fe3O4/SiO2/APTS

por Eshaghi Malekshah R, Fahimirad B, Khaleghian A
Publicado 2020

In vivo Pharmacokinetic and Anticancer Studies of HH-N25, a Selective Inhibitor of Topoisomerase I, and Hormonal Signaling for Treating Breast Cancer

por Lawal B, Kuo YC, Sumitra MR, Wu ATH, Huang HS
Publicado 2021

Insights into idarubicin antimicrobial activity against methicillin-resistant Staphylococcus aureus

por Pengfei She, Shijia Li, Linying Zhou, Zhen Luo, Jinfeng Liao, Lanlan Xu, Xianghai Zeng, Ti Chen, Yaqian Liu, Yong Wu
Publicado 2020

Three-Component Synthesis of 2-Amino-3-cyano-4<i>H</i>-chromenes, In Silico Analysis of Their Pharmacological Profile, and In Vitro Anticancer and Antifungal Testing

por Alberto Feliciano, Omar Gómez-García, Carlos H. Escalante, Mario A. Rodríguez-Hernández, Mariana Vargas-Fuentes, Dulce Andrade-Pavón, Lourdes Villa-Tanaca, Cecilio Álvarez-Toledano, María Teresa Ramírez-Apan, Miguel A. Vázquez, Joaquín Tamariz, Francisco Delgado
Publicado 2021