Deimmunization of flagellin for repeated administration as a vaccine adjuvant

por Koemchhoy Khim, Yong Jun Bang, Sao Puth, Yoonjoo Choi, Youn Suhk Lee, Kwangjoon Jeong, Shee Eun Lee, Joon Haeng Rhee
Publicado 2021

Highly conserved, non-human-like, and cross-reactive SARS-CoV-2 T cell epitopes for COVID-19 vaccine design and validation

por Lauren M. Meyers, Andres H. Gutiérrez, Christine M. Boyle, Frances Terry, Bethany G. McGonnigal, Andres Salazar, Michael F. Princiotta, Wiliam D. Martin, Anne S. De Groot, Leonard Moise
Publicado 2021

Genomic diversity contributes to the neuroinvasiveness of the Yellow fever French neurotropic vaccine

por Florian Bakoa, Christophe Préhaud, Guillaume Beauclair, Maxime Chazal, Nathalie Mantel, Monique Lafon, Nolwenn Jouvenet
Publicado 2021

The effect of SARS-CoV-2 D614G mutation on BNT162b2 vaccine-elicited neutralization

por Jing Zou, Xuping Xie, Camila R. Fontes-Garfias, Kena A. Swanson, Isis Kanevsky, Kristin Tompkins, Mark Cutler, David Cooper, Philip R. Dormitzer, Pei-Yong Shi
Publicado 2021

Author Correction: Personalized cancer vaccine strategy elicits polyfunctional T cells and demonstrates clinical benefits in ovarian cancer

por Janos L. Tanyi, Cheryl L.-L. Chiang, Johanna Chiffelle, Anne-Christine Thierry, Petra Baumgartener, Florian Huber, Christine Goepfert, David Tarussio, Stephanie Tissot, Drew A. Torigian, Harvey L. Nisenbaum, Brian J. Stevenson, Hajer Fritah Guiren, Ritaparna Ahmed, Anne-Laure Huguenin-Bergenat, Emese Zsiros, Michal Bassani-Sternberg, Rosemarie Mick, Daniel J. Powell, George Coukos, Alexandre Harari, Lana E. Kandalaft
Publicado 2021

Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates

por Kevin O. Saunders, Norbert Pardi, Robert Parks, Sampa Santra, Zekun Mu, Laura Sutherland, Richard Scearce, Maggie Barr, Amanda Eaton, Giovanna Hernandez, Derrick Goodman, Michael J. Hogan, Istvan Tombacz, David N. Gordon, R. Wes Rountree, Yunfei Wang, Mark G. Lewis, Theodore C. Pierson, Chris Barbosa, Ying Tam, Xiaoying Shen, Guido Ferrari, Georgia D. Tomaras, David C. Montefiori, Drew Weissman, Barton F. Haynes
Publicado 2021

Immunofocusing humoral immunity potentiates the functional efficacy of the AnAPN1 malaria transmission-blocking vaccine antigen

por Nicole G. Bender, Prachi Khare, Juan Martinez, Rebecca E. Tweedell, Vincent O. Nyasembe, Borja López-Gutiérrez, Abhai Tripathi, Dustin Miller, Timothy Hamerly, Eric M. Vela, Ryan R. Davis, Randall F. Howard, Sandrine Nsango, Ronald R. Cobb, Matthias Harbers, Rhoel R. Dinglasan
Publicado 2021

A Chlamydia trachomatis VD1-MOMP vaccine elicits cross-neutralizing and protective antibodies against C/C-related complex serovars

por Anja Weinreich Olsen, Ida Rosenkrands, Martin J. Holland, Peter Andersen, Frank Follmann
Publicado 2021

Recommendations for acceleration of vaccine development and emergency use filings for COVID-19 leveraging lessons from the novel oral polio vaccine

por Natalie Thiel, Casey Selwyn, Georgina Murphy, Shmona Simpson, Ajoy C. Chakrabarti
Publicado 2021

Intranasal powder live attenuated influenza vaccine is thermostable, immunogenic, and protective against homologous challenge in ferrets

por Jasmina M. Luczo, Tatiana Bousse, Scott K. Johnson, Cheryl A. Jones, Nicholas Pearce, Carlie A. Neiswanger, Min-Xuan Wang, Erin A. Miller, Nikolai Petrovsky, David E. Wentworth, Victor Bronshtein, Mark Papania, Stephen M. Tompkins
Publicado 2021

Clinicopathological Analysis and Demographic Features of Ocular Malignancies

por Al-Mujaini A, Maurya RP, Bosak S, Karan MK, Roy M, Singh VP, Singh MK, Kumar A, Singh S
Publicado 2021

The effect of calcium and magnesium on activity, immunogenicity, and efficacy of a recombinant N1/N2 neuraminidase vaccine

por Luca T. Giurgea, Jae-Keun Park, Kathie-Anne Walters, Kelsey Scherler, Adriana Cervantes-Medina, Ashley Freeman, Luz Angela Rosas, John C. Kash, Jeffery K. Taubenberger, Matthew J. Memoli
Publicado 2021

Protective efficacy of a SARS-CoV-2 DNA vaccine in wild-type and immunosuppressed Syrian hamsters

por Rebecca L. Brocato, Steven A. Kwilas, Robert K. Kim, Xiankun Zeng, Lucia M. Principe, Jeffrey M. Smith, Jay W. Hooper
Publicado 2021

A new generation needle- and adjuvant-free trivalent plague vaccine utilizing adenovirus-5 nanoparticle platform

por Paul B. Kilgore, Jian Sha, Jourdan A. Andersson, Vladimir L. Motin, Ashok K. Chopra
Publicado 2021

Onchocerca volvulus bivalent subunit vaccine induces protective immunity in genetically diverse collaborative cross recombinant inbred intercross mice

por Nathan M. Ryan, Jessica A. Hess, Fernando Pardo-Manuel de Villena, Benjamin E. Leiby, Ayako Shimada, Lei Yu, Amir Yarmahmoodi, Nikolai Petrovsky, Bin Zhan, Maria Elena Bottazzi, Benjamin L. Makepeace, Sara Lustigman, David Abraham
Publicado 2021

The double-sided effects of Mycobacterium Bovis bacillus Calmette–Guérin vaccine

por Junli Li, Lingjun Zhan, Chuan Qin
Publicado 2021

Relative effectiveness of influenza vaccines in elderly persons in the United States, 2012/2013-2017/2018 seasons

por Marina Amaral de Avila Machado, Cristiano S. Moura, Michal Abrahamowicz, Brian J. Ward, Louise Pilote, Sasha Bernatsky
Publicado 2021

Assessment of genetic changes and neurovirulence of shed Sabin and novel type 2 oral polio vaccine viruses

por Rahnuma Wahid, Laina Mercer, Andrew Macadam, Sarah Carlyle, Laura Stephens, Javier Martin, Konstantin Chumakov, Majid Laassri, Svetlana Petrovskaya, Saskia L. Smits, Koert J. Stittelaar, Chris Gast, William C. Weldon, Jennifer L. Konopka-Anstadt, M. Steven Oberste, Pierre Van Damme, Ilse De Coster, Ricardo Rüttimann, Ananda Bandyopadhyay, John Konz
Publicado 2021

A single dose of replication-competent VSV-vectored vaccine expressing SARS-CoV-2 S1 protects against virus replication in a hamster model of severe COVID-19

por Delphine C. Malherbe, Drishya Kurup, Christoph Wirblich, Adam J. Ronk, Chad Mire, Natalia Kuzmina, Noor Shaik, Sivakumar Periasamy, Matthew A. Hyde, Julie M. Williams, Pei-Yong Shi, Matthias J. Schnell, Alexander Bukreyev
Publicado 2021

Ad26.COV2.S protects Syrian hamsters against G614 spike variant SARS-CoV-2 and does not enhance respiratory disease

por Joan E. M. van der Lubbe, Sietske K. Rosendahl Huber, Aneesh Vijayan, Liesbeth Dekking, Ella van Huizen, Jessica Vreugdenhil, Ying Choi, Miranda R. M. Baert, Karin Feddes-de Boer, Ana Izquierdo Gil, Marjolein van Heerden, Tim J. Dalebout, Sebenzile K. Myeni, Marjolein Kikkert, Eric J. Snijder, Leon de Waal, Koert J. Stittelaar, Jeroen T. B. M. Tolboom, Jan Serroyen, Leacky Muchene, Leslie van der Fits, Lucy Rutten, Johannes P. M. Langedijk, Dan H. Barouch, Hanneke Schuitemaker, Roland C. Zahn, Frank Wegmann
Publicado 2021