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  1. 5741
    Basmisanil, a highly selective GABAA-α5 negative allosteric modulator: preclinical pharmacology and demonstration of functional target engagement in man
    “...Abstract GABAA-α5 subunit-containing receptors have been shown to play a key modulatory role...”
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  2. 5742
    Concurrent mutations in RNA-dependent RNA polymerase and spike protein emerged as the epidemiologically most successful SARS-CoV-2 variant
    “...Abstract The D614G mutation in the Spike protein of the SARS-CoV-2 has effectively replaced...”
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  3. 5743
    A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19
    “... to the receptor binding domain of the SARS-CoV-2 spike protein and show that an engineered homotrimeric Nb...”
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  4. 5744
    Glycan reactive anti-HIV-1 antibodies bind the SARS-CoV-2 spike protein but do not block viral entry
    “...Abstract The SARS-CoV-2 spike glycoprotein is a focal point for vaccine immunogen and therapeutic...”
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  5. 5745
    Standard blood laboratory values as a clinical support tool to distinguish between SARS-CoV-2 positive and negative patients
    “... COVID-19 patients suspected to be infected with SARS-CoV-2, who underwent PCR testing in one of five...”
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  6. 5746
    In silico comparison of SARS-CoV-2 spike protein-ACE2 binding affinities across species and implications for virus origin
    “...Abstract The devastating impact of the COVID-19 pandemic caused by SARS–coronavirus 2 (SARS-CoV-2...”
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  7. 5747
    How a Patient Personalised Clinical Pharmacy Programme Can Secure Therapeutic Care in an Orthogeriatric Care Pathway (5P Project)?
    “...Marine Barral,1,* Julie Martin,1,* Emmanuelle Carre,2 Audrey Janoly-Dumenil,3– 5 Florence...”
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  8. 5748
    G protein-coupled receptor kinase 5 deletion suppresses synovial inflammation in a murine model of collagen antibody-induced arthritis
    “...Abstract G protein-coupled receptor kinase 5 (GRK5) regulates inflammatory responses via...”
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  9. 5749
    Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1α/SIRT1-dependent transcriptional regulation of mitochondrial function
    “...Perilipin 5 has been implicated as a modulator of lipase activity and a scaffold linking lipid...”
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  10. 5750
    Tissue-specific expression of the SARS-CoV-2 receptor, angiotensin-converting enzyme 2, in mouse models of chronic kidney disease
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  11. 5751
    miR-181c-5p mediates apoptosis of vascular endothelial cells induced by hyperoxemia via ceRNA crosstalk
    “.... Hyperoxia significantly up-regulated miR-181c-5p expression, while down-regulated the expressions of NCAPG...”
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  12. 5752
    Structural insights into Legionella RidL-Vps29 retromer subunit interaction reveal displacement of the regulator TBC1D5
    “... displacement of the regulator TBC1D5....”
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  13. 5753
    Computational evidence for nitro derivatives of quinoline and quinoline N-oxide as low-cost alternative for the treatment of SARS-CoV-2 infection
    “...Abstract A new and more aggressive strain of coronavirus, known as SARS-CoV-2, which is highly...”
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  14. 5754
    IL-1β mediated nanoscale surface clustering of integrin α5β1 regulates the adhesion of mesenchymal stem cells
    “... in an α5β1 integrin-specific manner. Further, through quantitative super-resolution imaging we elucidated...”
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  15. 5755
    Survival of the enveloped bacteriophage Phi6 (a surrogate for SARS-CoV-2) in evaporated saliva microdroplets deposited on glass surfaces
    “... as good models for respiratory pathogens: the enveloped Phi6 (a surrogate for SARS-CoV-2), and the non...”
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  16. 5756
    The 4G/5G Polymorphism of Plasminogen Activator Inhibitor Type 1 is a Predictor of Moderate-to-Severe Thyroid Eye Disease
    Materias: “...4g/5g polymorphism...”
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  17. 5757
    Deposition distribution of the new coronavirus (SARS-CoV-2) in the human airways upon exposure to cough-generated droplets and aerosol particles
    “... respiratory syndrome coronavirus 2 (SARS-CoV-2). It infects the cells binding to the angiotensin-converting...”
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  18. 5758
    The human EDAR 370V/A polymorphism affects tooth root morphology potentially through the modification of a reaction–diffusion system
    “... clarified that a nonsynonymous variant in the ectodysplasin A receptor gene (EDAR 370V/A; rs3827760...”
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  19. 5759
    Integrated Bioinformatic Analysis of SARS-CoV-2 Infection Related Genes ACE2, BSG and TMPRSS2 in Aerodigestive Cancers
    por He C, Hua X, Sun S, Li S, Wang J, Huang X
    Publicado 2021
    “...@sysucc.org.cnBackground: Cancer patients are more vulnerable to severe acute respiratory syndrome coronavirus 2 (SARS-CoV...”
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  20. 5760
    SOX-5 activates a novel RORγt enhancer to facilitate experimental autoimmune encephalomyelitis by promoting Th17 cell differentiation
    “... new enhancer for RORγt, RORCE2, which synergizes with another TF, Sox5, for binding with RORγ...”
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