The antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting.

por Andrew E Shaw, Suzannah J Rihn, Nardus Mollentze, Arthur Wickenhagen, Douglas G Stewart, Richard J Orton, Srikeerthana Kuchi, Siddharth Bakshi, Mila Rodriguez Collados, Matthew L Turnbull, Joseph Busby, Quan Gu, Katherine Smollett, Connor G G Bamford, Elena Sugrue, Paul C D Johnson, Ana Filipe Da Silva, Alfredo Castello, Daniel G Streicker, David L Robertson, Massimo Palmarini, Sam J Wilson
Publicado 2021

The Δ40p53 isoform inhibits p53-dependent eRNA transcription and enables regulation by signal-specific transcription factors during p53 activation.

por Cecilia B Levandowski, Taylor Jones, Margaret Gruca, Sivapriya Ramamoorthy, Robin D Dowell, Dylan J Taatjes
Publicado 2021

Macroevolutionary thermodynamics: Temperature and the tempo of evolution in the tropics.

por Daniel L Rabosky
Publicado 2021

Do psychiatric diseases follow annual cyclic seasonality?

por Hanxin Zhang, Atif Khan, Qi Chen, Henrik Larsson, Andrey Rzhetsky
Publicado 2021

Glycerol suppresses glucose consumption in trypanosomes through metabolic contest.

por Stefan Allmann, Marion Wargnies, Nicolas Plazolles, Edern Cahoreau, Marc Biran, Pauline Morand, Erika Pineda, Hanna Kulyk, Corinne Asencio, Oriana Villafraz, Loïc Rivière, Emmanuel Tetaud, Brice Rotureau, Arnaud Mourier, Jean-Charles Portais, Frédéric Bringaud
Publicado 2021

Structural characterization of the Plasmodium falciparum lactate transporter PfFNT alone and in complex with antimalarial compound MMV007839 reveals its inhibition mechanism.

por Xi Peng, Nan Wang, Angqi Zhu, Hanwen Xu, Jialu Li, Yanxia Zhou, Chen Wang, Qingjie Xiao, Li Guo, Fei Liu, Zhi-Jun Jia, Huaichuan Duan, Jianping Hu, Weidan Yuan, Jia Geng, Chuangye Yan, Xin Jiang, Dong Deng
Publicado 2021

On the optimality of the enzyme-substrate relationship in bacteria.

por Hugo Dourado, Matteo Mori, Terence Hwa, Martin J Lercher
Publicado 2021

Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling.

por Taylor P Light, Delphine Brun, Pablo Guardado-Calvo, Riccardo Pederzoli, Ahmed Haouz, Frank Neipel, Félix A Rey, Kalina Hristova, Marija Backovic
Publicado 2021

The induction of preterm labor in rhesus macaques is determined by the  strength of immune response to intrauterine infection.

por Monica Cappelletti, Pietro Presicce, Ma Feiyang, Paranthaman Senthamaraikannan, Lisa A Miller, Matteo Pellegrini, Myung S Sim, Alan H Jobe, Senad Divanovic, Sing Sing Way, Claire A Chougnet, Suhas G Kallapur
Publicado 2021

A phylogenomic framework for charting the diversity and evolution of giant viruses.

por Frank O Aylward, Mohammad Moniruzzaman, Anh D Ha, Eugene V Koonin
Publicado 2021

Stimulation of the left dorsolateral prefrontal cortex with slow rTMS enhances verbal memory formation.

por Mircea van der Plas, Verena Braun, Benjamin Johannes Stauch, Simon Hanslmayr
Publicado 2021

Adult medial habenula neurons require GDNF receptor GFRα1 for synaptic stability and function.

por Diana Fernández-Suárez, Favio A Krapacher, Katarzyna Pietrajtis, Annika Andersson, Lilian Kisiswa, Alvaro Carrier-Ruiz, Marco A Diana, Carlos F Ibáñez
Publicado 2021

Exploring bacterial diversity via a curated and searchable snapshot of archived DNA sequences.

por Grace A Blackwell, Martin Hunt, Kerri M Malone, Leandro Lima, Gal Horesh, Blaise T F Alako, Nicholas R Thomson, Zamin Iqbal
Publicado 2021

The noncoding small RNA SsrA is released by Vibrio fischeri and modulates critical host responses.

por Silvia Moriano-Gutierrez, Clotilde Bongrand, Tara Essock-Burns, Leo Wu, Margaret J McFall-Ngai, Edward G Ruby
Publicado 2020

iSDAsoil: The first continent-scale soil property map at 30 m resolution provides a soil information revolution for Africa.

por Matthew A E Miller, Keith D Shepherd, Bruce Kisitu, Jamie Collinson
Publicado 2021

The microbiome impacts host hybridization and speciation.

por Asia K Miller, Camille S Westlake, Karissa L Cross, Brittany A Leigh, Seth R Bordenstein
Publicado 2021

Transgenerational inheritance of centromere identity requires the CENP-A N-terminal tail in the C. elegans maternal germ line.

por Reinier F Prosée, Joanna M Wenda, Isa Özdemir, Caroline Gabus, Kamila Delaney, Francoise Schwager, Monica Gotta, Florian A Steiner
Publicado 2021

Transposon debris in ciliate genomes.

por Yi Feng, Laura F Landweber
Publicado 2021

Exosomes mediate LTB4 release during neutrophil chemotaxis.

por Ritankar Majumdar, Aidin Tavakoli Tameh, Subhash B Arya, Carole A Parent
Publicado 2021

High-throughput characterization of photocrosslinker-bearing ion channel variants to map residues critical for function and pharmacology.

por Nina Braun, Søren Friis, Christian Ihling, Andrea Sinz, Jacob Andersen, Stephan A Pless
Publicado 2021