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  1. 3921
    MMP20-generated amelogenin cleavage products prevent formation of fan-shaped enamel malformations
    “... formation in wild-type (WT), Amelx −/− and Mmp20 −/− mouse mandibular incisors using focused ion beam...”
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  2. 3922
    COX-1/PGE2/EP4 alleviates mucosal injury by upregulating β-arr1-mediated Akt signaling in colitis
    “... and induce EP4 expression during dextran sulfate sodium (DSS)-induced colitis in wild-type (WT) mice...”
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  3. 3923
    Fluorometric evaluation of CYP3A4 expression using improved transgenic HepaRG cells carrying a dual-colour reporter for CYP3A4 and CYP3A7
    “... metabolism by CYP3A4 in these HepLCs was comparable to that in wild-type HepLCs. The EGFP fluorescence...”
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  4. 3924
    Role of Cytochrome P450 (CYP)1A in Hyperoxic Lung Injury: Analysis of the Transcriptome and Proteome
    “... Phase Proteomic Array. Wild type (WT), Cyp1a1−/− and Cyp1a2−/− (8–10 wk, C57BL/6J background) mice were...”
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  5. 3925
    Leukocytic Toll-Like Receptor 2 Deficiency Preserves Cardiac Function And Reduces Fibrosis In Sustained Pressure Overload
    “.... We induced pressure overload via transverse aortic constriction (TAC) in TLR2−/− and wild type (WT...”
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  6. 3926
    Suppression of cell migration by phospholipase C-related catalytically inactive protein-dependent modulation of PI3K signalling
    “.... Consistent with these results, in comparison with wild-type cells, Prip-deficient mouse embryonic fibroblasts...”
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  7. 3927
    STAT1 gain-of-function heterozygous cell models reveal diverse interferon-signature gene transcriptional responses
    “..., transcriptional polarization was evident among mutants compared with wild type, and this was maintained following...”
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  8. 3928
    Development and characterization of a monoclonal antibody blocking human TRPM4 channel
    “... TRPM4 current and ameliorated hypoxia-induced cell swelling. Using wild type rats, neither antibody...”
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  9. 3929
    Hepatocyte PRMT1 protects from alcohol induced liver injury by modulating oxidative stress responses
    “... wild type and S297A PRMT1 protected hepatocytes from oxidative stress induced apoptosis, however S297D...”
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  10. 3930
    Double deletion of tetraspanins CD9 and CD81 in mice leads to a syndrome resembling accelerated aging
    “... survival than wild-type (WT) mice. Consistent with this, DNA microarray analysis of DKO mouse lungs...”
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  11. 3931
    Glucansucrase (mutant) enzymes from Lactobacillus reuteri 180 efficiently transglucosylate Stevia component rebaudioside A, resulting in a superior taste
    “... sweeteners but suffer from a lingering bitterness. The Lactobacillus reuteri 180 wild-type glucansucrase Gtf...”
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  12. 3932
    Functional expression of CLIFAHDD and IHPRF pathogenic variants of the NALCN channel in neuronal cells reveals both gain- and loss-of-function properties
    “.... Several original properties of the wild-type (wt) NALCN current were retrieved: mainly carried by external...”
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  13. 3933
    Enzalutamide response in a panel of prostate cancer cell lines reveals a role for glucocorticoid receptor in enzalutamide resistant disease
    “... separation of responders and non-responders, predominantly related to status of wild-type AR. Surprisingly...”
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  14. 3934
    NaV1.5 knockout in iPSCs: a novel approach to study NaV1.5 variants in a human cardiomyocyte environment
    “... velocity Ca2+ transient waves propagation velocities were slow. A wild-type (WT) NaV1.5 channel expressed...”
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  15. 3935
    Virally-vectored vaccine candidates against white-nose syndrome induce anti-fungal immune response in little brown bats (Myotis lucifugus)
    “.... We conducted two trials to assess potential WNS vaccine candidates in wild-caught Myotis lucifugus...”
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  16. 3936
    Capsid amino acids at positions 247 and 270 are involved in the virulence of betanodaviruses to European sea bass
    “... replicated on E-11 cells, although showing some differences compared to the wild type virus, suggesting...”
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  17. 3937
    GmSYP24, a putative syntaxin gene, confers osmotic/drought, salt stress tolerances and ABA signal pathway
    “... exhibited insensitivity to osmotic/drought and high salinity. However, wild type soybean, Arabidopsis...”
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  18. 3938
    E3 ubiquitin ligase Nedd4 inhibits AP-1 activity and TNF-α production through targeting p38α for polyubiquitination and subsequent degradation
    por Qingjun Liu, Shihui Zhang, Gan Chen, Hong Zhou
    Publicado 2017
    “... response to LPS compared with wild-type cells. AP-1 activity and degradation of p38α were induced by Nedd4...”
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  19. 3939
    Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells
    “... (kl/kl) mice than in wild-type mice. In adrenalectomized kl/kl mice, spironolactone treatment still...”
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  20. 3940
    Susceptibility of cyclin-dependent kinase inhibitor 1-deficient mice to rheumatoid arthritis arising from interleukin-1β-induced inflammation
    “... and cartilage tissues in RA. The knee joints of p21-knockout (p21−/−) (n = 16) and wild type C57BL/6 (p21...”
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