SHOC2 phosphatase-dependent RAF dimerization mediates resistance to MEK inhibition in RAS-mutant cancers

por Greg G. Jones, Isabel Boned del Río, Sibel Sari, Aysen Sekerim, Lucy C. Young, Nicole Hartig, Itziar Areso Zubiaur, Mona A. El-Bahrawy, Rob E. Hynds, Winnie Lei, Miriam Molina-Arcas, Julian Downward, Pablo Rodriguez-Viciana
Publicado 2019

Unassisted solar lignin valorisation using a compartmented photo-electro-biochemical cell

por Myohwa Ko, Le Thanh Mai Pham, Young Jin Sa, Jinwoo Woo, Trang Vu Thien Nguyen, Jae Hyung Kim, Dongrak Oh, Pankaj Sharma, Jungki Ryu, Tae Joo Shin, Sang Hoon Joo, Yong Hwan Kim, Ji-Wook Jang
Publicado 2019

Precise capture and dynamic relocation of nanoparticulate biomolecules through dielectrophoretic enhancement by vertical nanogap architectures

por Eui-Sang Yu, Hyojin Lee, Sun-Mi Lee, Jiwon Kim, Taehyun Kim, Jongsu Lee, Chulki Kim, Minah Seo, Jae Hun Kim, Young Tae Byun, Seung-Chul Park, Seung-Yeol Lee, Sin-Doo Lee, Yong-Sang Ryu
Publicado 2020

Efficacy and feasibility of proton beam radiotherapy using the simultaneous integrated boost technique for locally advanced pancreatic cancer

por Tae Hyun Kim, Woo Jin Lee, Sang Myung Woo, Eun Sang Oh, Sang Hee Youn, Hye Young Jang, Sung-Sik Han, Sang-Jae Park, Yang-Gun Suh, Sung Ho Moon, Sang Soo Kim, Dae Yong Kim
Publicado 2020

Discovery and quality analysis of a comprehensive set of structural variants and short tandem repeats

por David Jakubosky, Erin N. Smith, Matteo D’Antonio, Marc Jan Bonder, William W. Young Greenwald, Agnieszka D’Antonio-Chronowska, Hiroko Matsui, i2QTL Consortium, Oliver Stegle, Stephen B. Montgomery, Christopher DeBoever, Kelly A. Frazer
Publicado 2020

SON drives oncogenic RNA splicing in glioblastoma by regulating PTBP1/PTBP2 switching and RBFOX2 activity

por Jung-Hyun Kim, Kyuho Jeong, Jianfeng Li, James M. Murphy, Lana Vukadin, Joshua K. Stone, Alexander Richard, Johnny Tran, G. Yancey Gillespie, Erik K. Flemington, Robert W. Sobol, Ssang-Teak Steve Lim, Eun-Young Erin Ahn
Publicado 2021

Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation

por Yadi Wu, Yu Wang, Yiwei Lin, Yajuan Liu, Yifan Wang, Jianhang Jia, Puja Singh, Young-In Chi, Chi Wang, Chenfang Dong, Wei Li, Min Tao, Dana Napier, Qiuying Shi, Jiong Deng, B Mark Evers, Binhua P. Zhou
Publicado 2017

Spin-orbit torque-driven skyrmion dynamics revealed by time-resolved X-ray microscopy

por Seonghoon Woo, Kyung Mee Song, Hee-Sung Han, Min-Seung Jung, Mi-Young Im, Ki-Suk Lee, Kun Soo Song, Peter Fischer, Jung-Il Hong, Jun Woo Choi, Byoung-Chul Min, Hyun Cheol Koo, Joonyeon Chang
Publicado 2017

YAP1 mediates survival of ALK-rearranged lung cancer cells treated with alectinib via pro-apoptotic protein regulation

por Takahiro Tsuji, Hiroaki Ozasa, Wataru Aoki, Shunsuke Aburaya, Tomoko Yamamoto Funazo, Koh Furugaki, Yasushi Yoshimura, Masatoshi Yamazoe, Hitomi Ajimizu, Yuto Yasuda, Takashi Nomizo, Hironori Yoshida, Yuichi Sakamori, Hiroaki Wake, Mitsuyoshi Ueda, Young Hak Kim, Toyohiro Hirai
Publicado 2020

Desensitized chimeric antigen receptor T cells selectively recognize target cells with enhanced antigen expression

por Chungyong Han, Su-Jung Sim, Seon-Hee Kim, Rohit Singh, Sunhee Hwang, Yu I. Kim, Sang H. Park, Kwang H. Kim, Don G. Lee, Ho S. Oh, Sangeun Lee, Young H. Kim, Beom K. Choi, Byoung S. Kwon
Publicado 2018

NADPH oxidase 4 is required for the generation of macrophage migration inhibitory factor and host defense against Toxoplasma gondii infection

por Ji Hye Kim, Jina Lee, Su-Jin Bae, Yeeun Kim, Byung-Joon Park, Jae-Won Choi, Jaeyul Kwon, Guang-Ho Cha, Heon Jong Yoo, Eun-Kyeong Jo, Yun Soo Bae, Young-Ha Lee, Jae-Min Yuk
Publicado 2017

Near-island biological hotspots in barren ocean basins

por Jamison M. Gove, Margaret A. McManus, Anna B. Neuheimer, Jeffrey J. Polovina, Jeffrey C. Drazen, Craig R. Smith, Mark A. Merrifield, Alan M. Friedlander, Julia S. Ehses, Charles W. Young, Amanda K. Dillon, Gareth J. Williams
Publicado 2016

Human brain metastatic stroma attracts breast cancer cells via chemokines CXCL16 and CXCL12

por Brile Chung, Ali A. Esmaeili, Sailesh Gopalakrishna-Pillai, John P. Murad, Emily S. Andersen, Naveen Kumar Reddy, Gayathri Srinivasan, Brian Armstrong, Caleb Chu, Young Kim, Tommy Tong, James Waisman, John H. Yim, Behnam Badie, Peter P. Lee
Publicado 2017

Background frequency can enhance the prognostication power of EEG patterns categories in comatose cardiac arrest survivors: a prospective, multicenter, observational cohort study

por Youn-Jung Kim, Min-Jee Kim, Yong Hwan Kim, Chun Song Youn, In Soo Cho, Su Jin Kim, Jung Hee Wee, Yoo Seok Park, Joo Suk Oh, Dong Hoon Lee, Won Young Kim, the Korean Hypothermia Network Investigators
Publicado 2021

Human kidney organoids model the tacrolimus nephrotoxicity and elucidate the role of autophagy

por Jin Won Kim, Sun Ah Nam, Eunjeong Seo, Jong Young Lee, Dohui Kim, Ji Hyeon Ju, Sun Woo Lim, Hong Lim Kim, Hyung Wook Kim, Chul Woo Yang, Jin Kim, Dong Sung Kim, Yong Kyun Kim
Publicado 2021

Effect of intraoperative fluid volume on postoperative ileus after robot-assisted radical cystectomy

por Ji Sung Shim, Tae Il Noh, Ja Hyeon Ku, Sangchul Lee, Tae Gyun Kwon, Tae-Hwan Kim, Seung Hyun Jeon, Sang Hyup Lee, Jong Kil Nam, Wan Seok Kim, Byong Chang Jeong, Ji Youl Lee, Sung Hoo Hong, Koon Ho Rha, Woong Kyu Han, Won Sik Ham, Young Goo Lee, Yong Seong Lee, Sung Yul Park, Young Eun Yoon, Sung Gu Kang, Jong Jin Oh, Seok Ho Kang, Korean Robot Assisted Radical Cystectomy (KORARC) Study Group
Publicado 2021

Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication

por Wayne Vuong, Muhammad Bashir Khan, Conrad Fischer, Elena Arutyunova, Tess Lamer, Justin Shields, Holly A. Saffran, Ryan T. McKay, Marco J. van Belkum, Michael A. Joyce, Howard S. Young, D. Lorne Tyrrell, John C. Vederas, M. Joanne Lemieux
Publicado 2020

Development of background-free tame fluorescent probes for intracellular live cell imaging

por Samira Husen Alamudi, Rudrakanta Satapathy, Jihyo Kim, Dongdong Su, Haiyan Ren, Rajkumar Das, Lingna Hu, Enrique Alvarado-Martínez, Jung Yeol Lee, Christian Hoppmann, Eduardo Peña-Cabrera, Hyung-Ho Ha, Hee-Sung Park, Lei Wang, Young-Tae Chang
Publicado 2016

Functional significance of U2AF1 S34F mutations in lung adenocarcinomas

por Mohammad S. Esfahani, Luke J. Lee, Young-Jun Jeon, Ryan A. Flynn, Henning Stehr, Angela B. Hui, Noriko Ishisoko, Eric Kildebeck, Aaron M. Newman, Scott V. Bratman, Matthew H. Porteus, Howard Y. Chang, Ash A. Alizadeh, Maximilian Diehn
Publicado 2019

Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5

por Sungjun Park, Seungwon Lee, Choong-Gu Lee, Guk Yeol Park, Hyebeen Hong, Jeon-Soo Lee, Young Min Kim, Sung Bae Lee, Daehee Hwang, Youn Soo Choi, John D. Fryer, Sin-Hyeog Im, Seung-Woo Lee, Yoontae Lee
Publicado 2017