A scalable, secure, and interoperable platform for deep data-driven health management

por Amir Bahmani, Arash Alavi, Thore Buergel, Sushil Upadhyayula, Qiwen Wang, Srinath Krishna Ananthakrishnan, Amir Alavi, Diego Celis, Dan Gillespie, Gregory Young, Ziye Xing, Minh Hoang Huynh Nguyen, Audrey Haque, Ankit Mathur, Josh Payne, Ghazal Mazaheri, Jason Kenichi Li, Pramod Kotipalli, Lisa Liao, Rajat Bhasin, Kexin Cha, Benjamin Rolnik, Alessandra Celli, Orit Dagan-Rosenfeld, Emily Higgs, Wenyu Zhou, Camille Lauren Berry, Katherine Grace Van Winkle, Kévin Contrepois, Utsab Ray, Keith Bettinger, Somalee Datta, Xiao Li, Michael P. Snyder
Publicado 2021

ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer.

por Maria Kalyuga, David Gallego-Ortega, Heather J Lee, Daniel L Roden, Mark J Cowley, C Elizabeth Caldon, Andrew Stone, Stephanie L Allerdice, Fatima Valdes-Mora, Rosalind Launchbury, Aaron L Statham, Nicola Armstrong, M Chehani Alles, Adelaide Young, Andrea Egger, Wendy Au, Catherine L Piggin, Cara J Evans, Anita Ledger, Tilman Brummer, Samantha R Oakes, Warren Kaplan, Julia M W Gee, Robert I Nicholson, Robert L Sutherland, Alexander Swarbrick, Matthew J Naylor, Susan J Clark, Jason S Carroll, Christopher J Ormandy
Publicado 2012

Detection of air and surface contamination by SARS-CoV-2 in hospital rooms of infected patients

por Po Ying Chia, Kristen Kelli Coleman, Yian Kim Tan, Sean Wei Xiang Ong, Marcus Gum, Sok Kiang Lau, Xiao Fang Lim, Ai Sim Lim, Stephanie Sutjipto, Pei Hua Lee, Than The Son, Barnaby Edward Young, Donald K. Milton, Gregory C. Gray, Stephan Schuster, Timothy Barkham, Partha Pratim De, Shawn Vasoo, Monica Chan, Brenda Sze Peng Ang, Boon Huan Tan, Yee-Sin Leo, Oon-Tek Ng, Michelle Su Yen Wong, Kalisvar Marimuthu, for the Singapore 2019 Novel Coronavirus Outbreak Research Team
Publicado 2020

The driver landscape of sporadic chordoma

por Patrick S. Tarpey, Sam Behjati, Matthew D. Young, Inigo Martincorena, Ludmil B. Alexandrov, Sarah J. Farndon, Charlotte Guzzo, Claire Hardy, Calli Latimer, Adam P. Butler, Jon W. Teague, Adam Shlien, P. Andrew Futreal, Sohrab Shah, Ali Bashashati, Farzad Jamshidi, Torsten O. Nielsen, David Huntsman, Daniel Baumhoer, Sebastian Brandner, Jay Wunder, Brendan Dickson, Patricia Cogswell, Josh Sommer, Joanna J. Phillips, M. Fernanda Amary, Roberto Tirabosco, Nischalan Pillay, Stephen Yip, Michael R. Stratton, Adrienne M. Flanagan, Peter J. Campbell
Publicado 2017

Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice

por Prasanta K. Dash, Rafal Kaminski, Ramona Bella, Hang Su, Saumi Mathews, Taha M. Ahooyi, Chen Chen, Pietro Mancuso, Rahsan Sariyer, Pasquale Ferrante, Martina Donadoni, Jake A. Robinson, Brady Sillman, Zhiyi Lin, James R. Hilaire, Mary Banoub, Monalisha Elango, Nagsen Gautam, R. Lee Mosley, Larisa Y. Poluektova, JoEllyn McMillan, Aditya N. Bade, Santhi Gorantla, Ilker K. Sariyer, Tricia H. Burdo, Won-Bin Young, Shohreh Amini, Jennifer Gordon, Jeffrey M. Jacobson, Benson Edagwa, Kamel Khalili, Howard E. Gendelman
Publicado 2019

Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression

por Astrid De Boeck, Bo Young Ahn, Charlotte D’Mello, Xueqing Lun, Shyam V. Menon, Mana M. Alshehri, Frank Szulzewsky, Yaoqing Shen, Lubaba Khan, Ngoc Ha Dang, Elliott Reichardt, Kimberly-Ann Goring, Jennifer King, Cameron J. Grisdale, Natalie Grinshtein, Dolores Hambardzumyan, Karlyne M. Reilly, Michael D. Blough, J. Gregory Cairncross, V. Wee Yong, Marco A. Marra, Steven J. M. Jones, David R. Kaplan, Kathy D. McCoy, Eric C. Holland, Pinaki Bose, Jennifer A. Chan, Stephen M. Robbins, Donna L. Senger
Publicado 2020

Global patterns in genomic diversity underpinning the evolution of insecticide resistance in the aphid crop pest Myzus persicae

por Kumar Saurabh Singh, Erick M. G. Cordeiro, Bartlomiej J. Troczka, Adam Pym, Joanna Mackisack, Thomas C. Mathers, Ana Duarte, Fabrice Legeai, Stéphanie Robin, Pablo Bielza, Hannah J. Burrack, Kamel Charaabi, Ian Denholm, Christian C. Figueroa, Richard H. ffrench-Constant, Georg Jander, John T. Margaritopoulos, Emanuele Mazzoni, Ralf Nauen, Claudio C. Ramírez, Guangwei Ren, Ilona Stepanyan, Paul A. Umina, Nina V. Voronova, John Vontas, Martin S. Williamson, Alex C. C. Wilson, Gao Xi-Wu, Young-Nam Youn, Christoph T. Zimmer, Jean-Christophe Simon, Alex Hayward, Chris Bass
Publicado 2021

Author Correction: Stretchable, dynamic covalent polymers for soft, long-lived bioresorbable electronic stimulators designed to facilitate neuromuscular regeneration

por Yeon Sik Choi, Yuan-Yu Hsueh, Jahyun Koo, Quansan Yang, Raudel Avila, Buwei Hu, Zhaoqian Xie, Geumbee Lee, Zheng Ning, Claire Liu, Yameng Xu, Young Joong Lee, Weikang Zhao, Jun Fang, Yujun Deng, Seung Min Lee, Abraham Vázquez-Guardado, Iwona Stepien, Ying Yan, Joseph W. Song, Chad Haney, Yong Suk Oh, Wentai Liu, Hong-Joon Yoon, Anthony Banks, Matthew R. MacEwan, Guillermo A. Ameer, Wilson Z. Ray, Yonggang Huang, Tao Xie, Colin K. Franz, Song Li, John A. Rogers
Publicado 2021

Clinical features and predictors of severity in COVID-19 patients with critical illness in Singapore

por Ser Hon Puah, Barnaby Edward Young, Po Ying Chia, Vui Kian Ho, Jiashen Loh, Roshni Sadashiv Gokhale, Seow Yen Tan, Duu Wen Sewa, Shirin Kalimuddin, Chee Keat Tan, Surinder K. M. S. Pada, Matthew Edward Cove, Louis Yi Ann Chai, Purnima Parthasarathy, Benjamin Choon Heng Ho, Jensen Jiansheng Ng, Li Min Ling, John A. Abisheganaden, Vernon J. M. Lee, Cher Heng Tan, Raymond T. P. Lin, Yee Sin Leo, David C. Lye, Tsin Wen Yeo, Singapore 2019 novel coronavirus outbreak research team
Publicado 2021

Stretchable, dynamic covalent polymers for soft, long-lived bioresorbable electronic stimulators designed to facilitate neuromuscular regeneration

por Yeon Sik Choi, Yuan-Yu Hsueh, Jahyun Koo, Quansan Yang, Raudel Avila, Buwei Hu, Zhaoqian Xie, Geumbee Lee, Zheng Ning, Claire Liu, Yameng Xu, Young Joong Lee, Weikang Zhao, Jun Fang, Yujun Deng, Seung Min Lee, Abraham Vázquez-Guardado, Iwona Stepien, Ying Yan, Joseph W. Song, Chad Haney, Yong Suk Oh, Wentai Liu, Hong-Joon Yoon, Anthony Banks, Matthew R. MacEwan, Guillermo A. Ameer, Wilson Z. Ray, Yonggang Huang, Tao Xie, Colin K. Franz, Song Li, John A. Rogers
Publicado 2020

Structural dynamics in the water and proton channels of photosystem II during the S2 to S3 transition

por Rana Hussein, Mohamed Ibrahim, Asmit Bhowmick, Philipp S. Simon, Ruchira Chatterjee, Louise Lassalle, Margaret Doyle, Isabel Bogacz, In-Sik Kim, Mun Hon Cheah, Sheraz Gul, Casper de Lichtenberg, Petko Chernev, Cindy C. Pham, Iris D. Young, Sergio Carbajo, Franklin D. Fuller, Roberto Alonso-Mori, Alex Batyuk, Kyle D. Sutherlin, Aaron S. Brewster, Robert Bolotovsky, Derek Mendez, James M. Holton, Nigel W. Moriarty, Paul D. Adams, Uwe Bergmann, Nicholas K. Sauter, Holger Dobbek, Johannes Messinger, Athina Zouni, Jan Kern, Vittal K. Yachandra, Junko Yano
Publicado 2021

Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma

por Sam Behjati, Patrick S. Tarpey, Kerstin Haase, Hongtao Ye, Matthew D. Young, Ludmil B. Alexandrov, Sarah J. Farndon, Grace Collord, David C. Wedge, Inigo Martincorena, Susanna L. Cooke, Helen Davies, William Mifsud, Mathias Lidgren, Sancha Martin, Calli Latimer, Mark Maddison, Adam P. Butler, Jon W. Teague, Nischalan Pillay, Adam Shlien, Ultan McDermott, P. Andrew Futreal, Daniel Baumhoer, Olga Zaikova, Bodil Bjerkehagen, Ola Myklebost, M. Fernanda Amary, Roberto Tirabosco, Peter Van Loo, Michael R. Stratton, Adrienne M. Flanagan, Peter J. Campbell
Publicado 2017

Longitudinal single-cell profiling reveals molecular heterogeneity and tumor-immune evolution in refractory mantle cell lymphoma

por Shaojun Zhang, Vivian Changying Jiang, Guangchun Han, Dapeng Hao, Junwei Lian, Yang Liu, Rongjia Zhang, Joseph McIntosh, Ruiping Wang, Minghao Dang, Enyu Dai, Yuanxin Wang, David Santos, Maria Badillo, Angela Leeming, Zhihong Chen, Kimberly Hartig, John Bigcal, Jia Zhou, Rashmi Kanagal-Shamanna, Chi Young Ok, Hun Lee, Raphael E. Steiner, Jianhua Zhang, Xingzhi Song, Ranjit Nair, Sairah Ahmed, Alma Rodriquez, Selvi Thirumurthi, Preetesh Jain, Nicolaus Wagner-Bartak, Holly Hill, Krystle Nomie, Christopher Flowers, Andrew Futreal, Linghua Wang, Michael Wang
Publicado 2021

Intratumoural immune heterogeneity as a hallmark of tumour evolution and progression in hepatocellular carcinoma

por Phuong H. D. Nguyen, Siming Ma, Cheryl Z. J. Phua, Neslihan A. Kaya, Hannah L. H. Lai, Chun Jye Lim, Jia Qi Lim, Martin Wasser, Liyun Lai, Wai Leong Tam, Tony K. H. Lim, Wei Keat Wan, Tracy Loh, Wei Qiang Leow, Yin Huei Pang, Chung Yip Chan, Ser Yee Lee, Peng Chung Cheow, Han Chong Toh, Florent Ginhoux, Shridhar Iyer, Alfred W. C. Kow, Yock Young Dan, Alexander Chung, Brian K. P. Goh, Salvatore Albani, Pierce K. H. Chow, Weiwei Zhai, Valerie Chew
Publicado 2021

Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

por Alexandra L Young, Razvan V Marinescu, Neil P Oxtoby, Martina Bocchetta, Keir Yong, Nicholas C Firth, David M Cash, David L Thomas, Katrina M Dick, Jorge Cardoso, John van Swieten, Barbara Borroni, Daniela Galimberti, Mario Masellis, Maria Carmela Tartaglia, James B Rowe, Caroline Graff, Fabrizio Tagliavini, Giovanni B Frisoni, Robert Laforce, Elizabeth Finger, Alexandre de Mendonça, Sandro Sorbi, Jason D Warren, Sebastian Crutch, Nick C Fox, Sebastien Ourselin, Jonathan M Schott, Jonathan D Rohrer, Daniel C Alexander, The Genetic FTD Initiative (GENFI), The Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Publicado 2018

Effects of climate and land-use changes on fish catches across lakes at a global scale

por Yu-Chun Kao, Mark W. Rogers, David B. Bunnell, Ian G. Cowx, Song S. Qian, Orlane Anneville, T. Douglas Beard, Alexander Brinker, J. Robert Britton, René Chura-Cruz, Natasha J. Gownaris, James R. Jackson, Külli Kangur, Jeppe Kolding, Anatoly A. Lukin, Abigail J. Lynch, Norman Mercado-Silva, Rodrigo Moncayo-Estrada, Friday J. Njaya, Ilia Ostrovsky, Lars G. Rudstam, Alfred L. E. Sandström, Yuichi Sato, Humberto Siguayro-Mamani, Andy Thorpe, Paul A. M. van Zwieten, Pietro Volta, Yuyu Wang, András Weiperth, Olaf L. F. Weyl, Joelle D. Young
Publicado 2020

Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans

por Jae-Hyung Jin, Kyung-Tae Lee, Joohyeon Hong, Dongpil Lee, Eun-Ha Jang, Jin-Young Kim, Yeonseon Lee, Seung-Heon Lee, Yee-Seul So, Kwang-Woo Jung, Dong-Gi Lee, Eunji Jeong, Minjae Lee, Yu-Byeong Jang, Yeseul Choi, Myung Ha Lee, Ji-Seok Kim, Seong-Ryong Yu, Jin-Tae Choi, Jae-Won La, Haneul Choi, Sun-Woo Kim, Kyung Jin Seo, Yelin Lee, Eun Jung Thak, Jaeyoung Choi, Anna F. Averette, Yong-Hwan Lee, Joseph Heitman, Hyun Ah Kang, Eunji Cheong, Yong-Sun Bahn
Publicado 2020

DNA vaccination protects mice against Zika virus-induced damage to the testes

por Bryan D. Griffin, Kar Muthumani, Bryce M. Warner, Anna Majer, Mable Hagan, Jonathan Audet, Derek R. Stein, Charlene Ranadheera, Trina Racine, Marc-Antoine De La Vega, Jocelyne Piret, Stephanie Kucas, Kaylie N. Tran, Kathy L. Frost, Christine De Graff, Geoff Soule, Leanne Scharikow, Jennifer Scott, Gordon McTavish, Valerie Smid, Young K. Park, Joel N. Maslow, Niranjan Y. Sardesai, J. Joseph Kim, Xiao-jian Yao, Alexander Bello, Robbin Lindsay, Guy Boivin, Stephanie A. Booth, Darwyn Kobasa, Carissa Embury-Hyatt, David Safronetz, David B. Weiner, Gary P. Kobinger
Publicado 2017

Author Correction: Intratumoural immune heterogeneity as a hallmark of tumour evolution and progression in hepatocellular carcinoma

por Phuong H. D. Nguyen, Siming Ma, Cheryl Z. J. Phua, Neslihan A. Kaya, Hannah L. H. Lai, Chun Jye Lim, Jia Qi Lim, Martin Wasser, Liyun Lai, Wai Leong Tam, Tony K. H. Lim, Wei Keat Wan, Tracy Loh, Wei Qiang Leow, Yin Huei Pang, Chung Yip Chan, Ser Yee Lee, Peng Chung Cheow, Han Chong Toh, Florent Ginhoux, Shridhar Iyer, Alfred W. C. Kow, Yock Young Dan, Alexander Chung, Glen K. Bonney, Brian K. P. Goh, Salvatore Albani, Pierce K. H. Chow, Weiwei Zhai, Valerie Chew
Publicado 2021