The Small Molecule Alpha-Synuclein Aggregator, FN075, Enhances Alpha-Synuclein Pathology in Subclinical AAV Rat Models

por Rachel Kelly, Andrew G. Cairns, Jörgen Ådén, Fredrik Almqvist, Alexis-Pierre Bemelmans, Emmanuel Brouillet, Tommy Patton, Declan P. McKernan, Eilís Dowd
Publicado 2021

Novel Divergent Polar Bear-Associated Mastadenovirus Recovered from a Deceased Juvenile Polar Bear

por Anisha Dayaram, Kyriakos Tsangaras, Selvaraj Pavulraj, Walid Azab, Nicole Groenke, Gudrun Wibbelt, Florian Sicks, Nikolaus Osterrieder, Alex D. Greenwood
Publicado 2018

Pilot Study Assessing the Impact of Intrathecal Administration of Variants AAV-PHP.B and AAV-PHP.eB on Brain Transduction in Adult Rhesus Macaques

por Marie-Laure Arotcarena, Sandra Dovero, Nathalie Biendon, Nathalie Dutheil, Vincent Planche, Vincent Planche, Erwan Bezard, Benjamin Dehay
Publicado 2021

In Vivo Modelling of Hepatitis B Virus Subgenotype A1 Replication Using Adeno-Associated Viral Vectors

por Shonisani Wendy Limani, Njabulo Mnyandu, Abdullah Ely, Reubina Wadee, Anna Kramvis, Patrick Arbuthnot, Mohube Betty Maepa
Publicado 2021

Specificity and off-target effects of AAV8-TBG viral vectors for the manipulation of hepatocellular gene expression in mice

por Christos Kiourtis, Ania Wilczynska, Colin Nixon, William Clark, Stephanie May, Thomas G. Bird
Publicado 2021

Establishment of a HEK293T cell line able to site-specifically integrate and stably express GDNF by rAAV-2 vector

por Zhang,Jinju, Zhang,Yun, Liu,Xiaomei, Xiang,Jingjing, Zhang,Chun
Publicado 2016

Krabbe Disease: Prospects of Finding a Cure Using AAV Gene Therapy

por Gibran Nasir, Rajiv Chopra, Fiona Elwood, Seemin S. Ahmed
Publicado 2021

Editorial: The Versatile Role of Nicotinamide Adenine Dinucleotide in Immunity

por Björn Rissiek, Andreas H. Guse, Sahil Adriouch, Santina Bruzzone
Publicado 2021

VIRUSES OF THE PARVOVIRIDAE FAMILY: MOLECULAR GENETICAL ASPECTS OF REPRODUCTION AND MEDICAL IMPORTANCE

por A. Yu. Antipova, I. N. Lavrentieva
Publicado 2017

Transplantation of human embryonic stem cells alleviates motor dysfunction in AAV2-Htt171-82Q transfected rat model of Huntington’s disease

por Jaisan Islam, Kyoung Ha So, Elina KC, Hyeong Cheol Moon, Aryun Kim, Sang Hwan Hyun, Soochong Kim, Young Seok Park
Publicado 2021

In vivo genome editing at the albumin locus to treat methylmalonic acidemia

por Jessica L. Schneller, Ciaran M. Lee, Leah E. Venturoni, Randy J. Chandler, Ang Li, Sangho Myung, Thomas J. Cradick, Ayrea E. Hurley, William R. Lagor, Gang Bao, Charles P. Venditti
Publicado 2021

scAAVengr, a transcriptome-based pipeline for quantitative ranking of engineered AAVs with single-cell resolution

por Bilge E Öztürk, Molly E Johnson, Michael Kleyman, Serhan Turunç, Jing He, Sara Jabalameli, Zhouhuan Xi, Meike Visel, Valérie L Dufour, Simone Iwabe, Luis Felipe L Pompeo Marinho, Gustavo D Aguirre, José-Alain Sahel, David V Schaffer, Andreas R Pfenning, John G Flannery, William A Beltran, William R Stauffer, Leah C Byrne
Publicado 2021

Integration of adeno-associated virus (AAV) into the genomes of most Thai and Mongolian liver cancer patients does not induce oncogenesis

por Alejandro A. Schäffer, Dana A. Dominguez, Lesley M. Chapman, E. Michael Gertz, Anuradha Budhu, Marshonna Forgues, Jittiporn Chaisaingmongkol, Siritida Rabibhadana, Benjarath Pupacdi, Xiaolin Wu, Enkhjargal Bayarsaikhan, Curtis C. Harris, Mathuros Ruchirawat, Eytan Ruppin, Xin Wei Wang
Publicado 2021

Proteomic Landscape of Adeno-Associated Virus (AAV)-Producing HEK293 Cells

por Lisa Strasser, Stefano Boi, Felipe Guapo, Nicholas Donohue, Niall Barron, Alana Rainbow-Fletcher, Jonathan Bones
Publicado 2021

Targeted integration of EpCAM-specific CAR in human induced pluripotent stem cells and their differentiation into NK cells

por Shin Yi Tang, Shijun Zha, Zhicheng Du, Jieming Zeng, Detu Zhu, Yumei Luo, Shu Wang
Publicado 2021