USP25 Regulates the Proliferation and Apoptosis of Ovarian Granulosa Cells in Polycystic Ovary Syndrome by Modulating the PI3K/AKT Pathway via Deubiquitinating PTEN

por Yue Gao, Jiao Chen, Rui Ji, Jinli Ding, Yan Zhang, Jing Yang
Publicado 2021

Downregulation of miR-34a Promotes Proliferation and Inhibits Apoptosis of Rat Osteoarthritic Cartilage Cells by Activating PI3K/Akt Pathway

por Tao H, Cheng L, Yang R
Publicado 2020

Function of selected natural antidiabetic compounds with potential against cancer via modulation of the PI3K/AKT/mTOR cascade

por Agustina Dwi Retno Nurcahyanti, Adeline Jap, Jullietta Lady, Deka Prismawan, Farukh Sharopov, Rachid Daoud, Michael Wink, Mansour Sobeh
Publicado 2021

Costunolide-Induced Apoptosis via Promoting the Reactive Oxygen Species and Inhibiting AKT/GSK3β Pathway and Activating Autophagy in Gastric Cancer

por Cuixiang Xu, Xiaoyan Huang, Xiaohua Lei, Zhankui Jin, Min Wu, Xiao Liu, Xiao Liu, Yubin Huang, Yubin Huang, Xiangrong Zhao, Yue Xiong, Jingying Sun, Xianglong Duan, Jianhua Wang
Publicado 2021

Proinflammatory Responses of 1-Nitropyrene against RAW264.7 Macrophages through Akt Phosphorylation and NF-κB Pathways

por Ping-Kun Tsai, Shih-Pin Chen, Rosa Huang-Liu, Chun-Jung Chen, Wen-Ying Chen, Yan-Yan Ng, Yu-Hsiang Kuan
Publicado 2021

Fluctuations in AKT and PTEN Activity Are Linked by the E3 Ubiquitin Ligase cCBL

por Manuel Olazábal-Morán, Miriam Sánchez-Ortega, Laura Martínez-Muñoz, Carmen Hernández, Manuel S. Rodríguez, Mario Mellado, Ana C. Carrera
Publicado 2021

Periostin gene expression in neu-positive breast cancer cells is regulated by a FGFR signaling cross talk with TGFβ/PI3K/AKT pathways

por Cédrik Labrèche, David P. Cook, John Abou-Hamad, Julia Pascoal, Benjamin R. Pryce, Khalid N. Al-Zahrani, Luc A. Sabourin
Publicado 2021

Silencing FYVE, RhoGEF and PH domain containing 1 (FGD1) suppresses melanoma progression by inhibiting PI3K/AKT signaling pathway

por Zehao Niu, Yan Li, Yujian Xu, Weiqian Jiang, Ran Tao, Youbai Chen, Yan Han
Publicado 2021

Identifying the molecular targets and mechanisms of xuebijing injection for the treatment of COVID-19 via network pharmacology and molecular docking

por Zhao Tianyu, Guan Liying
Publicado 2021

Gastroprotective effects of Kangfuxin against water-immersion and restraint stress-induced gastric ulcer in rats: roles of antioxidation, anti-inflammation, and pro-survival

por Shan Lu, Daoshun Wu, Guibo Sun, Funeng Geng, Yongmei Shen, Jin Tan, Xiaobo Sun, Yun Luo
Publicado 2019

Mechanism of metastasis suppression by luteolin in breast cancer

por Cook MT
Publicado 2018

An image feature selection approach for dimensionality reduction based on kNN and SVM for AkT proteins

por Shruti Jain, Ayodeji Olalekan Salau
Publicado 2019

Aberrant expression of PI3K/AKT signaling is involved in apoptosis resistance of hepatocellular carcinoma

por Wang Zhuangqiang, Cui Xiaopeng, Hao Gaopeng, He Jiefeng
Publicado 2021

Calycosin-7-O-β-Glucoside Isolated from <i>Astragalus membranaceus</i> Promotes Osteogenesis and Mineralization in Human Mesenchymal Stem Cells

por Kyung-Ran Park, Ji Eun Park, Bomi Kim, Il Keun Kwon, Jin Tae Hong, Hyung-Mun Yun
Publicado 2021

Harmine Hydrochloride Mediates the Induction of G2/M Cell Cycle Arrest in Breast Cancer Cells by Regulating the MAPKs and AKT/FOXO3a Signaling Pathways

por Chae Won Ock, Gi Dae Kim
Publicado 2021

Inhibition of integrin subunit alpha 11 restrains gastric cancer progression through phosphatidylinositol 3-kinase/Akt pathway

por Haijun Zhang, Lin Zhang, Ming Lu
Publicado 2021

Targeting the PI3K/Akt/mTOR Pathway in Hepatocellular Carcinoma

por Eun Jin Sun, Miriam Wankell, Pranavan Palamuthusingam, Craig McFarlane, Lionel Hebbard
Publicado 2021

Genistein Regulates Lipid Metabolism via Estrogen Receptor β and Its Downstream Signal Akt/mTOR in HepG2 Cells

por Hong Qin, Ziyu Song, Horia Shaukat, Wenya Zheng
Publicado 2021

Halofuginone Sensitizes Lung Cancer Organoids to Cisplatin via Suppressing PI3K/AKT and MAPK Signaling Pathways

por Hefei Li, Yushan Zhang, Xiaomei Lan, Jianhua Yu, Changshuang Yang, Zhijian Sun, Ping Kang, Yi Han, Daping Yu
Publicado 2021

Autophagy Flux Correlates with Upregulation of AKT-1 in RAS Mutated Colon Cancer Cells

por Hamid Behrouj, Amir Mahmoudzadeh, Saeid Ghavami, Pooneh Mokarram
Publicado 2021