Mechanistic insights into the renoprotective role of curcumin in cisplatin-induced acute kidney injury: network pharmacology analysis and experimental validation

por Zhang Hui, Qing-Qing Dong, Hua-Pan Shu, Yu-Chi Tu, Qian-Qian Liao, Li-Jun Yao
Publicado 2021

Mechanism research on a bioactive resveratrol–PLA–gelatin porous nano-scaffold in promoting the repair of cartilage defect

por Yu F, Li M, Yuan Z, Rao F, Fang X, Jiang B, Wen Y, Zhang P
Publicado 2018

Circ_0030235 knockdown protects H9c2 cells against OGD/R-induced injury via regulation of miR-526b

por Yuquan Zhang, Shuzhu Liu, Limin Ding, Dawei Wang, Qiangqiang Li, Dongdong Li
Publicado 2021

Inhibition of Lipopolysaccharide-Induced Inflammatory Bone Loss by Saikosaponin D is Associated with Regulation of the RANKL/RANK Pathway

por Wu X, Zhao K, Fang X, Lu F, Zhang W, Song X, Chen L, Sun J, Chen H
Publicado 2021

Hsa_circRNA_103124 Upregulation in Crohn’s Disease Promotes Cell Proliferation and Inhibits Autophagy by Regulating the Hsa-miR-650/AKT2 Signaling Pathway

por Juan Yin, Fuyi Tong, Yulan Ye, Tong Hu, Lijuan Xu, Liping Zhang, Jianyun Zhu, Zhi Pang, Zhi Pang
Publicado 2021

Integrated Transcriptome and Multiple Activated Pathways in Endometrial Cancer

por Qi Jin, Qi Jin, Xiaohua Jiang, Xin Du, Weiping Hu, Shun Bai, Xian Wang, Bo Xu, Weidong Zhao, Weidong Zhao
Publicado 2021

Euxanthone inhibits traumatic spinal cord injury via anti-oxidative stress and suppression of p38 and PI3K/Akt signaling pathway in a rat model

por Yao Rubin, Ren Lirong, Wang Shiyong, Zhang Ming, Yang Kaishun
Publicado 2021

Chemoradiotherapy‐induced increase in Th17 cell frequency in cervical cancer patients is associated with therapy resistance and early relapse

por Laura Theobald, Russalina Stroeder, Patrick Melchior, Ioan Iulian Iordache, Tanja Tänzer, Meike Port, Birgit Glombitza, Stefanie Marx, David Schub, Christian Herr, Martin Hart, Nicole Ludwig, Eckart Meese, Yoo‐Jin Kim, Rainer Maria Bohle, Sigrun Smola, Christian Rübe, Erich Franz Solomayer, Barbara Walch‐Rückheim
Publicado 2021

Resveratrol Upregulates mmu-miR-363-3p via the PI3K-Akt Pathway to Improve Insulin Resistance Induced by a High-Fat Diet in Mice

por Shu L, Zhao H, Huang W, Hou G, Song G, Ma H
Publicado 2020

Effects of Midazolam on the Development of Adult Leydig Cells From Stem Cells In Vitro

por Xingyi Zhao, Minpeng Ji, Xin Wen, Dan Chen, Fu Huang, Xiaoju Guan, Xiaoju Guan, Jing Tian, Jing Tian, Jiajia Xie, Jingjing Shao, Jiexia Wang, Luoqi Huang, Han Lin, Leping Ye, Haolin Chen, Haolin Chen, Haolin Chen
Publicado 2021

FOXO3a and Its Regulators in Prostate Cancer

por Dominika Ewa Habrowska-Górczyńska, Marta Justyna Kozieł, Karolina Kowalska, Agnieszka Wanda Piastowska-Ciesielska
Publicado 2021

Anti-Cancer Properties of Coix Seed Oil against HT-29 Colon Cells through Regulation of the PI3K/AKT Signaling Pathway

por Chunlei Ni, Bailiang Li, Yangyue Ding, Yue Wu, Qiuye Wang, Jiarong Wang, Jianjun Cheng
Publicado 2021

Synergistic inhibition of colon cancer cell growth with nanoemulsion-loaded paclitaxel and PI3K/mTOR dual inhibitor BEZ235 through apoptosis

por Zou H, Li L, Garcia Carcedo I, Xu ZP, Monteiro M, Gu WY
Publicado 2016

Induction of PI3K/Akt-Mediated Apoptosis in Osteoclasts Is a Key Approach for Buxue Tongluo Pills to Treat Osteonecrosis of the Femoral Head

por Dan Wang, Yicheng Liu, Dandan Tang, Shujun Wei, Jiayi Sun, Lvqiang Ruan, Lin He, Ruolan Li, Qiang Ren, Xiaoping Tian, Yunhui Chen
Publicado 2021

Guava Leaf Extract Attenuates Insulin Resistance via the PI3K/Akt Signaling Pathway in a Type 2 Diabetic Mouse Model

por Yang Q, Wen YM, Shen J, Chen MM, Wen JH, Li ZM, Liang YZ, Xia N
Publicado 2020

Effect and Mechanism of Ganoderma lucidum Spores on Alleviation of Diabetic Cardiomyopathy in a Pilot in vivo Study

por Shaher F, Wang S, Qiu H, Hu Y, Zhang Y, Wang W, AL-Ward H, Abdulghani MAM, Baldi S, Zhou S
Publicado 2020

Bioactive components and mechanisms of poplar propolis in inhibiting proliferation of human hepatocellular carcinoma HepG2 cells

por Hui Liu, Junya Li, Wenwen Yuan, Shengyu Hao, Meng Wang, Fei Wang, Hongzhuan Xuan
Publicado 2021

Danlou Tablet Activates Autophagy of Vascular Adventitial Fibroblasts Through PI3K/Akt/mTOR to Protect Cells From Damage Caused by Atherosclerosis

por Li Wang, Tong Wu, Chunying Si, He Wang, Ke Yue, Shasha Shang, Xiaohui Li, Yushan Chen, Huaimin Guan
Publicado 2021

Palmitic acid-induced lipotoxicity promotes a novel interplay between Akt-mTOR, IRS-1, and FFAR1 signaling in pancreatic β-cells

por Marafie,Sulaiman K., Al-Shawaf,Eman M., Abubaker,Jehad, Arefanian,Hossein
Publicado 2019

Essential meiotic structure-specific endonuclease1 (EME1) promotes malignant features in gastric cancer cells via the Akt/GSK3B/CCND1 pathway

por Zhiguo Guo, Erbo Liang, Wei Li, Leilei Jiang, Fachao Zhi
Publicado 2021