Remifentanil pretreatment ameliorates H/R-induced cardiac microvascular endothelial cell dysfunction by regulating the PI3K/Akt/HIF-1α signaling pathway

par Xiaojun Li, Zhenping Gui, Huizi Liu, Shaojie Qian, Yanan Jia, Xiaopan Luo
Publié 2021

Oxytocin Protects Against Isoproterenol-Induced Cardiac Hypertrophy by Inhibiting PI3K/AKT Pathway via a lncRNA GAS5/miR-375-3p/KLF4-Dependent Mechanism

par Yuqiao Yang, Zhuoran Wang, Mengran Yao, Wei Xiong, Jun Wang, Yu Fang, Wei Yang, Haixia Jiang, Ning Song, Lan Liu, Jinqiao Qian
Publié 2021

Preclinical Evaluation of the HDAC Inhibitor Chidamide in Transformed Follicular Lymphoma

par Mengya Zhong, Mengya Zhong, Jinshui Tan, Jinshui Tan, Guangchao Pan, Guangchao Pan, Yuelong Jiang, Yuelong Jiang, Hui Zhou, Hui Zhou, Qian Lai, Qian Lai, Qinwei Chen, Qinwei Chen, Liyuan Fan, Liyuan Fan, Manman Deng, Manman Deng, Bing Xu, Bing Xu, Jie Zha, Jie Zha
Publié 2021

Estrogen Protects Articular Cartilage by Downregulating ASIC1a in Rheumatoid Arthritis

par Hang X, Zhang Z, Niu R, Wang C, Yao J, Xu Y, Tao J, Li L, Chen F
Publié 2021

Hexokinases 2 promoted cell motility and distant metastasis by elevating fibronectin through Akt1/p-Akt1 in cervical cancer cells

par Qian Chen, Lu Li, Xian Liu, Qian Feng, Yanru Zhang, Pengsheng Zheng, Nan Cui
Publié 2021

IL-10 Signaling Elicited by Nivolumab-Induced Activation of the MAP Kinase Pathway Does Not Fully Contribute to Nivolumab-Modulated Heterogeneous T Cell Responses

par Taylor A. Harper, Silvia M. Bacot, Christie Jane Fennell, Rebecca L. Matthews, Christina Zhu, Peng Yue, Alexander Benton, Devira Friedman, Adovi Akue, Mark A. KuKuruga, Shiowjen Lee, Tao Wang, Gerald M. Feldman
Publié 2021

Impairments of spatial learning and memory following intrahippocampal injection in rats of 3-mercaptopropionic acid-modified CdTe quantum dots and molecular mechanisms

par Wu T, He K, Ang S, Ying J, Zhang S, Zhang T, Xue Y, Tang M
Publié 2016

New Insights into Curcumin- and Resveratrol-Mediated Anti-Cancer Effects

par Andrea Arena, Maria Anele Romeo, Rossella Benedetti, Laura Masuelli, Roberto Bei, Maria Saveria Gilardini Montani, Mara Cirone
Publié 2021

Thymoquinone Potentiates the Effect of Phenytoin against Electroshock-Induced Convulsions in Rats by Reducing the Hyperactivation of m-TOR Pathway and Neuroinflammation: Evidence f...

par Faheem Hyder Pottoo, Mohammed Salahuddin, Firdos Alam Khan, Fadhel Alomar, Marwa Abdullah AL Dhamen, Abrar Fouad Alhashim, Hawra Hussain Alqattan, Mohamed S. Gomaa, Mohammad N. Alomary
Publié 2021

PI3K Pathway Inhibition with NVP-BEZ235 Hinders Glycolytic Metabolism in Glioblastoma Multiforme Cells

par Shreya Udawant, Carl Litif, Alma Lopez, Bonnie Gunn, Erin Schuenzel, Megan Keniry
Publié 2021

Benznidazole Anti-Inflammatory Effects in Murine Cardiomyocytes and Macrophages Are Mediated by Class I PI3Kδ

par Ágata C. Cevey, Ágata C. Cevey, Paula D. Mascolo, Federico N. Penas, Federico N. Penas, Azul V. Pieralisi, Aldana S. Sequeyra, Gerardo A. Mirkin, Gerardo A. Mirkin, Nora B. Goren, Nora B. Goren
Publié 2021

Drug connectivity mapping and functional analysis reveal therapeutic small molecules that differentially modulate myelination

par A.D. Rivera, F. Pieropan, G. Williams, F. Calzolari, A.M. Butt, K. Azim
Publié 2022

E2F transcription factor 1 is involved in the phenotypic modulation of esophageal squamous cell carcinoma cells via microRNA-375

par Pengfei Li, Huina Lv, Yongkai Wu, Ke Xu, Min Xu, Yegang Ma
Publié 2021

Clonorchis sinensis Granulin Promotes Malignant Transformation of Hepatocyte Through EGFR-Mediated RAS/MAPK/ERK and PI3K/Akt Signaling Pathways

par Caiqin Wang, Caiqin Wang, Caiqin Wang, Caiqin Wang, Caiqin Wang, Qing He, Qing He, Qing He, Qing He, Yingxuan Yin, Yingxuan Yin, Yingxuan Yin, Yingxuan Yin, Yinjuan Wu, Yinjuan Wu, Yinjuan Wu, Yinjuan Wu, Xuerong Li, Xuerong Li, Xuerong Li, Xuerong Li
Publié 2021

Investigation on the mechanisms of biochanin A alleviate PM10-induced acute pulmonary cell injury

par Shihao Li, Junyu Wang, Yue Yu, Bowen Zheng, Juan Ma, Xiaohong Kou, Zhaohui Xue
Publié 2021

Cerebroprotein Hydrolysate-I Inhibits Hippocampal Neuronal Apoptosis by Activating PI3K/Akt Signaling Pathway in Vascular Dementia Mice

par Wu X, Liu Y, Zhu L, Wang Y, Ren Y, Cheng B, Ren L, Ge K, Li H
Publié 2021

HO-1 protects the nerves of rats with cerebral hemorrhage by regulating the PI3K/AKT signaling pathway

par Zhao Q, Qu R, Teng L, Yin C, Yuan Y
Publié 2019

Effects of Hydroxysafflor Yellow A on the PI3K/AKT Pathway and Apoptosis of Pancreatic β-Cells in Type 2 Diabetes Mellitus Rats

par Lee M, Li H, Zhao H, Suo M, Liu D
Publié 2020

RNA-binding protein IGF2BP2 enhances circ_0000745 abundancy and promotes aggressiveness and stemness of ovarian cancer cells via the microRNA-3187-3p/ERBB4/PI3K/AKT axis

par Shengtan Wang, Zaihong Li, Genhai Zhu, Lan Hong, Chunyan Hu, Kang Wang, Kaiying Cui, Chunbo Hao
Publié 2021

Preclinical Evaluation of a Novel Dual Targeting PI3Kδ/BRD4 Inhibitor, SF2535, in B-Cell Acute Lymphoblastic Leukemia

par Yongsheng Ruan, Yongsheng Ruan, Hye Na Kim, Heather A. Ogana, Zesheng Wan, Samantha Hurwitz, Cydney Nichols, Nour Abdel-Azim, Ariana Coba, Seyoung Seo, Yong-Hwee Eddie Loh, Eun Ji Gang, Hisham Abdel-Azim, Chih-Lin Hsieh, Michael R. Lieber, Chintan Parekh, Dhananjay Pal, Deepa Bhojwani, Donald L. Durden, Donald L. Durden, Yong-Mi Kim
Publié 2021