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  1. 2081
    Protein disulfide isomerase family 6 promotes the imatinib-resistance of renal cell carcinoma by regulation of Wnt3a-Frizzled1 axis
    por Yong Huang, Ping He, Juan Ding
    Publicado 2021
    “... was suppressed by PDIA6 silencing, and the apoptosis was promoted with reduced Bcl-2, enhanced Bax and cleaved...”
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  2. 2082
    Phosphodiesterase-5 inhibition mimics intermittent reoxygenation and improves cardioprotection in the hypoxic myocardium.
    “... cumulative effects. The changes in myocardial cGMP, apoptosis (DNA fragmentation), caspase-3 activity...”
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  3. 2083
    Revisiting G3BP1 as a RasGAP binding protein: sensitization of tumor cells to chemotherapy by the RasGAP 317-326 sequence does not involve G3BP1.
    “... passenger complexes. It also negatively or positively regulates apoptosis depending on the extent of its...”
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  4. 2084
    Inhibition of endoplasmic reticulum stress improves mouse embryo development.
    “... density and significant ER stress-induced apoptosis. Tauroursodeoxycholic acid (TUDCA), a known inhibitor...”
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  5. 2085
    Expression and methylation of mitochondrial transcription factor a in chronic obstructive pulmonary disease patients with lung cancer.
    “...<h4>Background</h4>Apoptosis plays a central role in the pathogenesis of chronic obstructive...”
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  6. 2086
    DUSP1 is a novel target for enhancing pancreatic cancer cell sensitivity to gemcitabine.
    “.... Gemcitabine-induced JNK and p38 MAPK activation mediates increased apoptosis, but also transcriptionally...”
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  7. 2087
    Cardioprotective effects of Cu(II)ATSM in human vascular smooth muscle cells and cardiomyocytes mediated by Nrf2 and DJ-1
    “... of angiotensin II (Ang II) by attenuating superoxide generation, apoptosis, proliferation and increases...”
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  8. 2088
    α-SNAP is expressed in mouse ovarian granulosa cells and plays a key role in folliculogenesis and female fertility
    “... signaling, autophagy and apoptosis in different cell types. In this study we examined the expression pattern...”
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  9. 2089
    Synthesis and antitumor efficacy of daunorubicin-loaded magnetic nanoparticles
    por Jun Wang, Baoan Chen, Jian Chen, et al
    Publicado 2011
    “... assay. Furthermore, cell apoptosis and intracellular accumulation of DNR were determined by FACSCalibur...”
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  10. 2090
    Targeting EZH2 for glioma therapy with a novel nanoparticle&ndash;siRNA complex
    por Wang X, Hua Y, Xu G, Deng S, Yang D, Gao X
    Publicado 2019
    “... showed good anti-glioma effect in vitro through inducing cell apoptosis and inhibiting cell growth. What...”
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  11. 2091
    Preparation and characterization of novel chitosan-protamine nanoparticles for nucleus-targeted anticancer drug delivery
    por Yu X, Hou J, Shi Y, Su C, Zhao L
    Publicado 2016
    “..., and cell apoptosis on cells. Chitosan&ndash;protamine NPs were characterized by good drug entrapment...”
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  12. 2092
    Structural modulation of gut microbiota during alleviation of experimental passive Heymann nephritis in rats by a traditional Chinese herbal formula
    “..., relieving podocyte injury, and reducing glomerular and tubular cell apoptosis. The lower dose...”
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  13. 2093
    Analysis of the cytotoxicity of hierarchical nanoporous graphenic carbon against human glioblastoma grade IV cells
    “..., and the expression of genes engaged in apoptosis pathways are studied. The results demonstrate that cytotoxicity...”
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  14. 2094
    Sustained release of hepatocyte growth factor by cationic self-assembling peptide/heparin hybrid hydrogel improves &beta;-cell survival and function through modulating inflammatory response
    por Liu S, Zhang L, Cheng J, Lu Y, Liu J
    Publicado 2016
    “..., and the viability, apoptosis, function, and inflammation of &beta;-cells were evaluated. Cationic KLD1R and KLD2R...”
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  15. 2095
    Long Non-Coding RNA Lacuna Regulates Neuronal Differentiation of Neural Stem Cells During Brain Development
    “... proliferation or apoptosis of NSCs. CRISPR/dCas9-KRAB mediated knockdown of Lacuna gene expression leads...”
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  16. 2096
    Downregulation of Rap1GAP Expression Activates the TGF-β/Smad3 Pathway to Inhibit the Expression of Sodium/Iodine Transporter in Papillary Thyroid Carcinoma Cells
    “... was applied to analyze cell apoptosis and cycle. WB was performed to detect apoptotic-related proteins. Wound...”
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  17. 2097
    The high-performance technology CRISPR/Cas9 improves knowledge and management of acute myeloid leukemia
    “..., differentiation, growth, apoptosis, and self-renewal, the combined pathogenetic mechanisms involved...”
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  18. 2098
    Accumulation of LDL/ox-LDL in the necrotic region participates in osteonecrosis of the femoral head: a pathological and in vitro study
    “... viability, apoptosis, and metabolism process of LDL/ox-LDL in osteocytes in normoxic and hypoxic...”
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  19. 2099
    Evodiamine Inhibits Gastric Cancer Cell Proliferation via PTEN-Mediated EGF/PI3K Signaling Pathway
    “... was detected by high-content screening (HCS). The apoptosis-inducing effect of evodiamine on AGS and BGC-823...”
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  20. 2100
    Identifying intracellular signaling modules and exploring pathways associated with breast cancer recurrence
    “... with ER signaling and with cell cycle and apoptosis signaling. We validated IMPALA-identified pathway...”
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