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  1. 3141
    Target Sestrin2 to Rescue the Damaged Organ: Mechanistic Insight into Its Function
    por Moein Ala, Seyed Parsa Eftekhar
    Publicado 2021
    “... (ER) stress, apoptosis, fibrogenesis, and lipogenesis. Sestrin2 vigorously enhances M2 macrophage...”
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  2. 3142
    Quercetin Impact in Pancreatic Cancer: An Overview on Its Therapeutic Effects
    “..., apoptosis, cell growth reduction or inhibition, EMT, oxidative stress, and enhancing sensitivity...”
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  3. 3143
    Effects of the CK2 inhibitors CX-4945 and CX-5011 on drug-resistant cells.
    “... apoptosis, and normal-sensitive variant S. We found that the inhibition of endogenous CK2 was very similar...”
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  4. 3144
    Activation of Fms-like tyrosine kinase 3 signaling enhances survivin expression in a mouse model of rheumatoid arthritis.
    “...Survivin is known as an inhibitor of apoptosis and a positive regulator of cell division. We have...”
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  5. 3145
    Epithelial mesenchymal transition and pancreatic tumor initiating CD44+/EpCAM+ cells are inhibited by γ-secretase inhibitor IX.
    “...+ cells. Notably, apoptosis was induced after GSI IX treatment and EMT markers were selectively targeted...”
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  6. 3146
    Close interactions between mesenchymal stem cells and neuroblastoma cell lines lead to tumor growth inhibition.
    “... of apoptosis of NB cells and prolonged the survival of hMSC-treated mice. The need for contact between MSCs...”
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  7. 3147
    A peptidic unconjugated GRP78/BiP ligand modulates the unfolded protein response and induces prostate cancer cell death.
    “... and increased apoptosis in in vivo xenograft tumor models. Amino acid substitutions that destroyed binding...”
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  8. 3148
    Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma.
    “... of the BMP effectors Smad1/5/8. We have previously shown that BMP-7 potently induced apoptosis in normal B...”
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  9. 3149
    Transcriptional and Non-Transcriptional Functions of PPARβ/δ in Non-Small Cell Lung Cancer.
    “... proliferation and survival, while PPARβ/δ knock-down reduced viability and increased apoptosis. PPARβ/δ agonists...”
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  10. 3150
    NADPH oxidase NOX4 mediates stellate cell activation and hepatocyte cell death during liver fibrosis development.
    “... apoptosis in hepatocytes. Finally, NOX4 expression was elevated in patients with hepatitis C virus (HCV...”
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  11. 3151
    Prokaryotic caspase homologs: phylogenetic patterns and functional characteristics reveal considerable diversity.
    “...Caspases accomplish initiation and execution of apoptosis, a programmed cell death process specific...”
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  12. 3152
    Cardiac ankyrin repeat protein attenuates cardiac hypertrophy by inhibition of ERK1/2 and TGF-β signaling pathways.
    “... was not attributed to apoptosis.<h4>Conclusion</h4>CARP attenuates cardiac hypertrophy, in which the ERK and TGF-β...”
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  13. 3153
    POSSIBLE MECHANISMS OF STIMULATORY EFFECTS OF MESENCHYMAL STROMAL CELLS UPON T CELL RECOVERY DURING CHEMOTHERAPY-INDUCED LYMPHOPENIA
    “..., there was no an increase in apoptosis of naive CD4+T cells that was typical for standard AHSCT. These data indicate...”
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  14. 3154
    Quantitative phosphoproteomics of proteasome inhibition in multiple myeloma cells.
    “... upon bortezomib treatment, suggesting new mechanisms associated to bortezomib-induced apoptosis in MM...”
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  15. 3155
    VCP associated inclusion body myopathy and paget disease of bone knock-in mouse model exhibits tissue pathology typical of human disease.
    “... sections representing increased number of autophagosomes suggested impaired autophagy. Increased apoptosis...”
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  16. 3156
    ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancer.
    “... expression of ZIC1 suppresses cell proliferation and induces apoptosis, which is associated with MAPK and PI...”
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  17. 3157
    Frequent and simultaneous epigenetic inactivation of TP53 pathway genes in acute lymphoblastic leukemia.
    “..., Curcumin or Nutlin-3 induced an increase in apoptosis of ALL cells. The results obtained with the initial...”
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  18. 3158
    Maltose-binding protein enhances secretion of recombinant human granzyme B accompanied by in vivo processing of a precursor MBP fusion protein.
    “...<h4>Background</h4>The apoptosis-inducing serine protease granzyme B (GrB) is an important factor...”
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  19. 3159
    A key role for E-cadherin in intestinal homeostasis and Paneth cell maturation.
    “... intestine and colon resulted in bloody diarrhea associated with enhanced apoptosis and cell shedding...”
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  20. 3160
    Deletion of the fission yeast homologue of human insulinase reveals a TORC1-dependent pathway mediating resistance to proteotoxic stress.
    “...). Reduced sensitivity to tunicamycin was associated with a smaller number of cells undergoing apoptosis...”
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