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  1. 4561
    A dual-functional HER2 aptamer-conjugated, pH-activated mesoporous silica nanocarrier-based drug delivery system provides in vitro synergistic cytotoxicity in HER2-positive breast cancer cells
    por Shen Y, Li M, Liu T, Liu J, Xie Y, Zhang J, Xu S, Liu H
    Publicado 2019
    “... of HER2 inhibits cell proliferation and induces apoptosis. We aimed to exploit the potential of HApt...”
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  2. 4562
    Novel therapeutic mechanisms determine the effectiveness of lipid-core nanocapsules on melanoma models
    “... treatment (18–90×109 particles/mL; 1 hour) induced late apoptosis and necrosis; LNC and AcE...”
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  3. 4563
    Preparation and antitumor evaluation of self-assembling oleanolic acid-loaded Pluronic P105/D-α-tocopheryl polyethylene glycol succinate mixed micelles for non-small-cell lung cancer treatment
    “.... Apoptosis assays revealed that the apoptotic rate of OA-micelle-treated A549 and PC-9 cells was higher than...”
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  4. 4564
    Silver nanoparticles induce tight junction disruption and astrocyte neurotoxicity in a rat blood–brain barrier primary triple coculture model
    “.... Meanwhile, Ag-NPS induced inflammation and apoptosis through modulation of the MAPK pathway or B-cell...”
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  5. 4565
    Dexmedetomidine attenuates the propofol-induced long-term neurotoxicity in the developing brain of rats by enhancing the PI3K/Akt signaling pathway
    por Xiao Y, Zhou L, Tu Y, Li Y, Liang Y, Zhang X, Lv J, Zhong Y, Xie Y
    Publicado 2018
    “.... The neuronal apoptosis, expression of PSD95, expression and phosphorylation of Akt and GSK3β and synaptic...”
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  6. 4566
    DEAR1 is a dominant regulator of acinar morphogenesis and an independent predictor of local recurrence-free survival in early-onset breast cancer.
    “... of apical basal polarity, diffuse apoptosis, and failure of lumen formation. Furthermore...”
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  7. 4567
    Cyclam-Modified Polyethyleneimine for Simultaneous TGFβ siRNA Delivery and CXCR4 Inhibition for the Treatment of CCl4-Induced Liver Fibrosis
    “... decreased inflammation, collagen deposition, apoptosis, and cell proliferation, thus ameliorating liver...”
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  8. 4568
    1,25-Dihydroxyvitamin D Inhibits Osteoarthritis by Modulating Interaction Between Vitamin D Receptor and NLRP3 in Macrophages
    por Duan A, Ma Z, Liu W, Shen K, Zhou H, Wang S, Kong R, Shao Y, Chen Y, Guo W, Liu F
    Publicado 2021
    “...) and 1,25VD on chondrogenic proliferation, apoptosis, and migration. The immunofluorescence staining...”
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  9. 4569
    Encapsulating Halofuginone Hydrobromide in TPGS Polymeric Micelles Enhances Efficacy Against Triple-Negative Breast Cancer Cells
    “... induced cell cycle arrest and apoptosis of MDA-MB-231 by disrupting the mitochondrial membrane potential...”
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  10. 4570
    Dual Functional Eudragit® S100/L30D-55 and PLGA Colon-Targeted Nanoparticles of Iridoid Glycoside for Improved Treatment of Induced Ulcerative Colitis
    por Gao C, Yu S, Zhang X, Dang Y, Han D, Liu X, Han J, Hui M
    Publicado 2021
    “..., macroscopic score, histological damage and cell apoptosis. Our results also proved that the potent anti...”
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  11. 4571
    Nicotinamide Mononucleotide Alleviates Hyperosmolarity-Induced IL-17a Secretion and Macrophage Activation in Corneal Epithelial Cells/Macrophage Co-Culture System
    por Meng YF, Pu Q, Dai SY, Ma Q, Li X, Zhu W
    Publicado 2021
    “.... The cellular activity, including cell viability, apoptosis status and lactate dehydrogenase (LDH) release...”
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  12. 4572
    Electroacupuncture Promoting Axonal Regeneration in Spinal Cord Injury Rats via Suppression of Nogo/NgR and Rho/ROCK Signaling Pathway
    “... fluorescence quantitative PCR and Western blotting, respectively. Cell apoptosis changes in the spinal cord...”
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  13. 4573
    Glucose-coated Berberine Nanodrug for Glioma Therapy through Mitochondrial Pathway
    “... viability was measured by MTT assay and Western blotting analysis. Apoptosis was performed with flow...”
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  14. 4574
    Cerium oxide NPs mitigate the amyloid formation of α-synuclein and associated cytotoxicity
    “..., apoptosis, and the ratio of Bax/Bcl-2 gene expression associated with α-syn amyloids.Conclusion...”
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  15. 4575
    Transcriptome-Wide High-Throughput m6A Sequencing of Differential m6A Methylation Patterns in the Human Rheumatoid Arthritis Fibroblast-Like Synoviocytes Cell Line MH7A
    por Jiang H, Cao K, Fan C, Cui X, Ma Y, Liu J
    Publicado 2021
    “... in inflammation-related pathways, cell proliferation and apoptosis. In addition, the validations of WTAP, RIPK2...”
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  16. 4576
    Role of nucleus accumbens glutamatergic plasticity in drug addiction
    por Quintero GC
    Publicado 2013
    “... behaviors like self-administration and relapse. Neither apoptosis nor neurogenesis plays a relevant role...”
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  17. 4577
    Cationic Antheraea pernyi Silk Fibroin-Modified Adenovirus-Mediated ING4 and IL-24 Dual Gene Coexpression Vector Suppresses the Growth of Hepatoma Carcinoma Cells
    por Qu J, Wang W, Feng Y, Niu L, Li M, Yang J, Xie Y
    Publicado 2019
    “... apoptosis of hepatoma carcinoma SMMC-7721 cells. The viability of SMMC-7721 and L-02 cells infected...”
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  18. 4578
    Modulation of FLT3-ITD Localization and Targeting of Distinct Downstream Signaling Pathways as Potential Strategies to Overcome FLT3-Inhibitor Resistance
    “..., and characterized in terms of downstream signaling by immunoblotting. FLT3 surface expression, apoptosis...”
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  19. 4579
    Mangifera indica (Mango): A Promising Medicinal Plant for Breast Cancer Therapy and Understanding Its Potential Mechanisms of Action
    “... breast cancer cell growth, proliferation, migration and invasion as well as trigger apoptosis and cell...”
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  20. 4580
    Specific Cytotoxic Effect of an Auristatin Nanoconjugate Towards CXCR4+ Diffuse Large B-Cell Lymphoma Cells
    “... and apoptosis. Furthermore, the nanoconjugate shows a potent reduction in lymphoma mouse dissemination without...”
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