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  1. 30001
    Role of Alpelisib in the Treatment of PIK3CA-Mutated Breast Cancer: Patient Selection and Clinical Perspectives
    por Chang DY, Ma WL, Lu YS
    Publicado 2021
    “... major role in the growth and survival of cancer cells. Breast tumors often harbor PIK3CA gene...”
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  2. 30002
    Gut Microbiota-Derived Inflammation-Related Serum Metabolites as Potential Biomarkers for Major Depressive Disorder
    por Bai S, Xie J, Bai H, Tian T, Zou T, Chen JJ
    Publicado 2021
    “... gene sequencing was used to analyze the gut microbiota compositions in fecal samples.Results: Totally...”
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  3. 30003
    PLAUR as a Potential Biomarker Associated with Immune Infiltration in Bladder Urothelial Carcinoma
    por Liu M, Chen S, Zhang A, Zheng Q, Fu J
    Publicado 2021
    “... of PLAUR was positively associated with immune infiltration, and also the expression levels of gene markers...”
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  4. 30004
    Dual SGLT1/SGLT2 Inhibitor Phlorizin Ameliorates Non-Alcoholic Fatty Liver Disease and Hepatic Glucose Production in Type 2 Diabetic Mice
    “... (PEPCK), glucose-6-phosphatase (G6Pase) and glucose transporter 2 (Slc2a2 gene); hepatocyte nuclear...”
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  5. 30005
    Entresto protected the cardiomyocytes and preserved heart function in cardiorenal syndrome rat fed with high-protein diet through regulating the oxidative stress and Mfn2-mediated mitochondrial functional integrity
    “... and deletion of Mfn2 gene (i.e., shMfn2) to significantly reduce H2O2-induced ROS production. En significantly...”
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  6. 30006
    Hepatitis C virus E2 protein encapsulation into poly D, L-lactic-co-glycolide microspheres could induce mice cytotoxic T-cell response
    por Roopngam P, Liu K, Mei L, Zheng Y, Zhu X, Tsai HI, Huang L
    Publicado 2016
    “...; 2The Shenzhen Key Laboratory of Gene and Antibody Therapy, Center for Biotechnology and Biomedicine...”
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  7. 30007
    The reduction of volume and fiber bundle connections in the hippocampus of EGR3 transgenic schizophrenia rats
    por Ma E, Song T, Zhang H, Lu J, Wang L, Zhao Q, Guo R, Li M, Ma G, Lu G, Li K
    Publicado 2015
    “... of the EGR3 gene into rat hippocampus. All animals were placed in a fixation system using a commercial rat...”
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  8. 30008
    Macropinocytosis activated by oncogenic Dbl enables specific targeted delivery of Tat/pDNA nano-complexes into ovarian cancer cells
    por Niu X, Gao Z, Qi S, Su L, Yang N, Luan X, Li J, Zhang Q, An Y, Zhang S
    Publicado 2018
    “... *These authors contributed equally to this work Background: Successful implementation of gene therapy heavily...”
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  9. 30009
    Synthesis, characterization, and immune efficacy of layered double hydroxide@SiO2 nanoparticles with shell-core structure as a delivery carrier for Newcastle disease virus DNA vaccine
    “... expressing the Newcastle disease virus F gene. The LDH was hydrotalcite-like materials. The plasmid DNA...”
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  10. 30010
    The OXTR Polymorphism Stratified the Correlation of Oxytocin and Glucose Homeostasis in Non-Diabetic Subjects
    “... the effect is stratified by the polymorphism of oxytocin receptor gene (OXTR) remains unclear.Methods...”
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  11. 30011
    Codelivery of doxorubicin and MDR1-siRNA by mesoporous silica nanoparticles-polymerpolyethylenimine to improve oral squamous carcinoma treatment
    por Wang D, Xu X, Zhang K, Sun B, Wang L, Meng L, Liu Q, Zheng C, Yang B, Sun H
    Publicado 2017
    “... transfected with MSNP-PEI-DOX/MDR1-siRNA could effectively decrease gene expression of MDR1 (~70% increase...”
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  12. 30012
    Targeted polyethylene glycol gold nanoparticles for the treatment of pancreatic cancer: from synthesis to proof-of-concept in vitro studies
    “...-à-go-go related gene 1 (hERG1) channel aberrantly expressed on the membrane of pancreatic cancer...”
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  13. 30013
    Engineered outer membrane vesicle is potent to elicit HPV16E7-specific cellular immunity in a mouse model of TC-1 graft tumor
    por Wang S, Huang W, Li K, Yao Y, Yang X, Bai H, Sun W, Liu C, Ma Y
    Publicado 2017
    “... in engineered OMVs through gene recombinant techniques. Subcutaneous immunization with the engineered OMVs...”
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  14. 30014
    The presence of endophytic actinobacteria in mangosteen peel (Garcinia mangostana) and its antioxidant activity
    “... of spore chains. Based on 16S rRNA gene analysis, AGM3.2 isolate showed similarity with Streptomyces...”
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  15. 30015
    PM2.5 Aggravated OVA-Induced Epithelial Tight Junction Disruption Through Fas Associated via Death Domain-Dependent Apoptosis in Asthmatic Mice
    por He X, Zhang L, Hu L, Liu S, Xiong A, Wang J, Xiong Y, Li G
    Publicado 2021
    “... staining (H&E) and Masson’s trichrome. RNA-seq and gene set enrichment analysis (GSEA) was performed...”
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  16. 30016
    Effects of lighting regimes on performance, pineal melanopsin expression and melatonin content in native laying hens aged from 19 to 34 weeks
    “..., the relative expression of pineal melanopsin gene (Opn4 mRNA) was measured on 1 d at 9:00, 13:00, 17:00, 21:00...”
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  17. 30017
    Hydrocephalus – History of Surgical Treatment over the centuries
    por Ricardo Santos de Oliveira
    Publicado 2020
    “... in molecular biology, gene therapy, and neural regeneration, the concept of a functional cure may become...”
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  18. 30018
    Analysis of germline GLI1 variation implicates hedgehog signalling in the regulation of intestinal inflammatory pathways.
    “... demonstrate increased susceptibility to chemically induced colitis.<h4>Methods and findings</h4>Using a gene...”
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  19. 30019
    INFECTION OF LABOUR MIGRANTS FROM CENTRAL ASIA AND RESIDENTS OF ST. PETERSBURG AND THEIR SUSCEPTIBILITY TO VARIOUS INFECTIOUS DISEASES
    “... sign. In migrants 17% of C. diphtheriae strains have a “silent” gene (tox+), which, under known...”
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  20. 30020
    Co-Exposure of Cardiomyocytes to IFN-γ and TNF-α Induces Mitochondrial Dysfunction and Nitro-Oxidative Stress: Implications for the Pathogenesis of Chronic Chagas Disease Cardiomyopathy
    “...-sparing agonists of AMPK, NRF2 and SIRT1 rescues ΔΨm in IFN-γ/TNF-α-stimulated cells. Proteomic and gene...”
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