Vaccine-Induced Th1-Type Response Protects against Invasive Group A <italic toggle="yes">Streptococcus</italic> Infection in the Absence of Opsonizing Antibodies

por Tania Rivera-Hernandez, Mira Syahira Rhyme, Amanda J. Cork, Scott Jones, Celia Segui-Perez, Livia Brunner, Johanna Richter, Nikolai Petrovsky, Maria Lawrenz, David Goldblatt, Nicolas Collin, Mark J. Walker
Publicado 2020

An Experimental Group A <italic toggle="yes">Streptococcus</italic> Vaccine That Reduces Pharyngitis and Tonsillitis in a Nonhuman Primate Model

por Tania Rivera-Hernandez, Diane G. Carnathan, Scott Jones, Amanda J. Cork, Mark R. Davies, Peter M. Moyle, Istvan Toth, Michael R. Batzloff, James McCarthy, Victor Nizet, David Goldblatt, Guido Silvestri, Mark J. Walker
Publicado 2019

Development of an Opsonophagocytic Killing Assay Using HL-60 Cells for Detection of Functional Antibodies against <italic toggle="yes">Streptococcus pyogenes</italic>

por Sanaz Salehi, Claudia M. Hohn, Thomas A. Penfound, James B. Dale
Publicado 2018

Galectin-3 Inhibits Galectin-8/Parkin-Mediated Ubiquitination of Group A Streptococcus

por Yi-Lin Cheng, Yan-Wei Wu, Chih-Feng Kuo, Shiou-Ling Lu, Fu-Tong Liu, Robert Anderson, Chiou-Feng Lin, Yi-Ling Liu, Wan-Yu Wang, Ying-Da Chen, Po-Xing Zheng, Jiunn-Jong Wu, Yee-Shin Lin
Publicado 2017

The Arginine Deiminase Pathway Impacts Antibiotic Tolerance during Biofilm-Mediated <named-content content-type="genus-species">Streptococcus pyogenes</named-content> Infections

por Jeffrey A. Freiberg, Yoann Le Breton, Janette M. Harro, Devon L. Allison, Kevin S. McIver, Mark E. Shirtliff
Publicado 2020

T4 Pili Promote Colonization and Immune Evasion Phenotypes of Nonencapsulated M4 <named-content content-type="genus-species">Streptococcus pyogenes</named-content>

por Yi-Hsuan Chen, Shao-Hui Li, Yao-Cheng Yang, Shu-Hao Hsu, Victor Nizet, Yung-Chi Chang
Publicado 2020

RocA Regulates Phosphatase Activity of Virulence Sensor CovS of Group A <italic toggle="yes">Streptococcus</italic> in Growth Phase- and pH-Dependent Manners

por Chuan Chiang-Ni, He-Jing Chiou, Huei-Chuan Tseng, Chih-Yun Hsu, Cheng-Hsun Chiu
Publicado 2020

A Multicomponent Vaccine Provides Immunity against Local and Systemic Infections by Group A Streptococcus across Serotypes

por Shuai Bi, Meiyi Xu, Ya Zhou, Xinxin Xing, Adong Shen, Beinan Wang
Publicado 2019

Molecular Epidemiology of Noninvasive and Invasive Group A Streptococcal Infections in Cape Town

por D. D. Barth, P. Naicker, K. Engel, B. Muhamed, W. Basera, B. M. Mayosi, J. B. Dale, M. E. Engel
Publicado 2019

Antibiotic Treatment, Mechanisms for Failure, and Adjunctive Therapies for Infections by Group A Streptococcus

por Anders F. Johnson, Christopher N. LaRock, Christopher N. LaRock, Christopher N. LaRock, Christopher N. LaRock
Publicado 2021

Role of Glutathione in Buffering Excess Intracellular Copper in <italic toggle="yes">Streptococcus pyogenes</italic>

por Louisa J. Stewart, Cheryl-lynn Y. Ong, May M. Zhang, Stephan Brouwer, Liam McIntyre, Mark R. Davies, Mark J. Walker, Alastair G. McEwan, Kevin J. Waldron, Karrera Y. Djoko
Publicado 2020

The Emergence of Successful <named-content content-type="genus-species">Streptococcus pyogenes</named-content> Lineages through Convergent Pathways of Capsule Loss and Recombinatio...

por Claire E. Turner, Matthew T. G. Holden, Beth Blane, Carolyne Horner, Sharon J. Peacock, Shiranee Sriskandan
Publicado 2019

Systematic Review and Meta-analysis of the Prevalence of Group A Streptococcal <italic toggle="yes">emm</italic> Clusters in Africa To Inform Vaccine Development

por Taariq Salie, Kelin Engel, Annesinah Moloi, Babu Muhamed, James B. Dale, Mark E. Engel
Publicado 2020

Integrin α5β1, as a Receptor of Fibronectin, Binds the FbaA Protein of Group A <italic toggle="yes">Streptococcus</italic> To Initiate Autophagy during Infection

por Jiachao Wang, Meiqi Meng, Miao Li, Xiaofei Guan, Jianguo Liu, Xue Gao, Qingqing Sun, Jinquan Li, Cuiqing Ma, Lin Wei
Publicado 2020

Enrichment of Antigen-Specific Class-Switched B Cells from Individuals Naturally Immunized by Infection with Group A Streptococcus

por Cheri L. Lamb, Emily Price, Kevin P. Field, Christopher Dayton, Eric R. McIndoo, Eva J. Katahira, Dennis L. Stevens, Sarah E. Hobdey
Publicado 2019

Virulence Role of the GlcNAc Side Chain of the Lancefield Cell Wall Carbohydrate Antigen in Non-M1-Serotype Group A <italic toggle="yes">Streptococcus</italic>

por Anna Henningham, Mark R. Davies, Satoshi Uchiyama, Nina M. van Sorge, Sean Lund, Kelsey T. Chen, Mark J. Walker, Jason N. Cole, Victor Nizet
Publicado 2018

A Conserved Streptococcal Virulence Regulator Controls the Expression of a Distinct Class of M-Like Proteins

por Jonathan D. D’Gama, Zhe Ma, Hailong Zhang, Xu Liu, Hongjie Fan, Ellen Ruth A. Morris, Noah D. Cohen, Colette Cywes-Bentley, Gerald B. Pier, Matthew K. Waldor
Publicado 2019

A Controlled Human Infection Model of Group A <italic toggle="yes">Streptococcus</italic> Pharyngitis: Which Strain and Why?

por Joshua Osowicki, Kristy I. Azzopardi, Liam McIntyre, Tania Rivera-Hernandez, Cheryl-lynn Y. Ong, Ciara Baker, Christine M. Gillen, Mark J. Walker, Pierre R. Smeesters, Mark R. Davies, Andrew C. Steer
Publicado 2019

Group A Streptococcus Induces LAPosomes via SLO/β1 Integrin/NOX2/ROS Pathway in Endothelial Cells That Are Ineffective in Bacterial Killing and Suppress Xenophagy

por Yi-Lin Cheng, Chih-Feng Kuo, Shiou-Ling Lu, Hiroko Omori, Ya-Na Wu, Cheng-Lu Hsieh, Takeshi Noda, Shang-Rung Wu, Robert Anderson, Chiou-Feng Lin, Chia-Ling Chen, Jiunn-Jong Wu, Yee-Shin Lin
Publicado 2019

PURIFIED IGG F C-BINDING PROTEINS FROM M22 GROUP A STREPTOCOCCUS ARE ABLE TO INDUCE EXPERIMENTAL GLOMERULONEPHRITIS

por L. A. Burova, P. V. Pigarevsky, E. A. Gavrilova, V. G. Seliverstova, K. Schalen, Artem A. Totolyan, T. V. Gupalova
Publicado 2014