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  1. 7421
    Phase I Dose-Escalation Trial of an Innovative Chemotherapy Regimen Combining a Fractionated Dose of Irinotecan Plus Bevacizumab, Oxaliplatin, 5-Fluorouracil, and Folinic Acid (bFOLFIRINOX-3) in Chemorefractory Metastatic Colorectal Cancer
    “...>) and irinotecan (administered before and after 5-fluorouracil infusion), plus bevacizumab (5 mg/kg). In a “3 + 3...”
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  2. 7422
    Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD–scid IL-2rgnull RIP-DTR mice engrafted with human islets
    “... were treated with lixisenatide (50, 150, and 500 µg/kg) or vehicle. Islet function was determined...”
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  3. 7423
    The comparative immunotoxicity of mesoporous silica nanoparticles and colloidal silica nanoparticles in mice
    por Lee S, Kim MS, Lee D, Kwon TK, Khang D, Yun HS, Kim SH
    Publicado 2013
    “... structural conditions of silica NPs.Materials and methods: Both MPS and Col NPs (2, 20, and 50 mg/kg/day...”
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  4. 7424
    Pharmacokinetics and in vitro/in vivo antitumor efficacy of aptamer-targeted Ecoflex® nanoparticles for docetaxel delivery in ovarian cancer
    “... of Taxotere®, DTX-NPs, and Apt-DTX-NPs (at an equivalent dose of 5 mg/kg of DTX), pharmacokinetic...”
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  5. 7425
    NMDA receptors are expressed in human ovarian cancer tissues and human ovarian cancer cell lines
    por North WG, Liu F, Tian R, Abbasi H, Akerman B
    Publicado 2015
    “... xenografts with ifenprodil (2.5 mg/kg body weight/day) significantly reduced tumor growth in nu/nu mice. Our...”
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  6. 7426
    Nitric oxide-releasing nanoparticles improve doxorubicin anticancer activity
    “...). Subcutaneous administration of SMA-tDodSNO (1 mg/kg) to xenografted mice bearing 4T1 cells showed that SMA...”
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  7. 7427
    Effect of pre- and post-treatment with Bacopa monnieri (Brahmi) on phencyclidine-induced disruptions in object recognition memory and cerebral calbindin, parvalbumin, and calretinin immunoreactivity in rats
    por Piyabhan P, Tingpej P, Duansak N
    Publicado 2019
    “...), parvalbumin (PV), and calretinin (CR)) in a sub-chronic (2 mg/kg, Bid, ip) phencyclidine (PCP) rat model...”
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  8. 7428
    Pharmacokinetics, tissue distribution, and excretion of zinc oxide nanoparticles
    “... nanoparticles at a concentration below 300 mg/kg were distributed in tissues and excreted within 24 hours...”
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  9. 7429
    Preparation and characterization of monomethoxy poly(ethylene glycol)-poly(ε-caprolactone) micelles for the solubilization and in vivo delivery of luteolin
    “... was intravenously administered at a dose of 30 mg/kg in rats. Also, Lu/MPEG-PCL micelles maintained the cytotoxicity...”
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  10. 7430
    Efficacy and safety of a novel anti‐HER2 therapeutic antibody RC48 in patients with HER2‐overexpressing, locally advanced or metastatic gastric or gastroesophageal junction cancer: a single‐arm phase II study
    “... under at least second‐line therapy were eligible and received RC48 2.5 mg/kg alone every 2 weeks...”
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  11. 7431
    High prevalence and burden of adult malnutrition at a tertiary hospital: An opportunity to use nutrition-focused care to improve outcomes
    “... undernourished or at risk for malnutrition, based primarily on BMI < 18.5 kg/m2 or NRS-2002 score ≥ 3...”
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  12. 7432
    Effects of therapeutic plasma exchange on the endothelial glycocalyx in septic shock
    “... replacing eGC protective factors. Methods We enrolled 20 norepinephrine-dependent (NE > 0.4 μg/kg/min...”
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  13. 7433
    Pulse arrival time as a surrogate of blood pressure
    “... old, with a body mass index of 22.7 ± 3.2 kg/m $$^{2}$$ 2 ). Each session lasted on average 27.9 ± 0.6...”
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  14. 7434
    N-fertilizer postponing application improves dry matter translocation and increases system productivity of wheat/maize intercropping
    por Ke Xu, Qiang Chai, Falong Hu, Zhilong Fan, Wen Yin
    Publicado 2021
    “...) for maize and the total amount were all 360 kg N ha−1. N fertilizer were applied at four time, i.e. prior...”
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  15. 7435
    Progestin primed ovarian stimulation using corifollitropin alfa in PCOS women effectively prevents LH surge and reduces injection burden compared to GnRH antagonist protocol
    “.... This is a retrospective cohort study recruiting 333 women with PCOS, with body weight between 50 and 70 kg...”
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  16. 7436
    Crude and acid oils from olive pomace as alternative fat sources in growing-finishing pigs
    “... pens according to initial BW (58.7 ± 9.71 kg, mean ± SD) and sex. Four experimental treatments were...”
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  17. 7437
    Influence of Calving Ease on In-Line Milk Urea and Relationship with Other Milk Characteristics in Dairy Cows
    “..., the productivity of cows without dystocia at calving was higher (2.50–5.51 kg) as well as the milk protein % (0.13...”
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  18. 7438
    Supervivencia y rendimiento de variedades de frijol con resistencia horizontal a estrés hídrico en la Sierra Nororiental de Puebla
    “..., obtuvieron el mayor rendimiento potencial con 757 y 562 kg ha-1 respectivamente en la localidad de San Juan...”
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  19. 7439
    Metabolically Healthy Obesity (MHO) vs. Metabolically Unhealthy Obesity (MUO) Phenotypes in PCOS: Association with Endocrine-Metabolic Profile, Adherence to the Mediterranean Diet, and Body Composition
    “... population consisted of 94 treatment-naïve women with PCOS and obesity (BMI = 38.23 ± 6.62 kg/m<sup>2</sup...”
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  20. 7440
    Association of interleukin-6 signalling with the muscle stem cell response following muscle-lengthening contractions in humans.
    “... findings</h4>Eight subjects (age 22+/-1 y; 79+/-8 kg) performed 300 maximal unilateral lengthening...”
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