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  1. 6081
    miR-1226-3p Promotes eNOS Expression of Pulmonary Arterial Endothelial Cells to Mitigate Hypertension in Rats via Targeting Profilin-1
    por Jie Jian, Liang Xia
    Publicado 2021
    “...). Overexpressed Pfn1 led to decreased eNOS, while miR-1226-3p could partly inhibit the expression of Pfn1...”
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  2. 6082
    Chronic activation of the G protein-coupled receptor 30 with agonist G-1 attenuates heart failure.
    “... were also determined. Our data showed that ISO treatment led to heart failure in OVX rats. G-1 or E(2...”
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  3. 6083
    Organ-specific LPS-induced inflammatory gene expression in adult Zebrafish
    “... be dose-dependent, for instance the infusion of 20 µg LPS led to decrease of expression of IFNy, Mpeg 1.2...”
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  4. 6084
    Evolutionary genomics of transposable elements in Saccharomyces cerevisiae.
    “... and evolution of transposable elements. The availability of the S. cerevisiae genome led to unprecedented...”
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  5. 6085
    Application of a high throughput method of biomarker discovery to improvement of the EarlyCDT(®)-Lung Test.
    “...<h4>Background</h4>The National Lung Screening Trial showed that CT screening for lung cancer led...”
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  6. 6086
    Integrative analyses of hepatic differentially expressed genes and blood biomarkers during the peripartal period between dairy cows overfed or restricted-fed energy prepartum.
    “.... OF led to greater prepartal liver distress accompanied by a low-grade inflammation and larger proteolysis...”
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  7. 6087
    Incorrect likelihood methods were used to infer scaling laws of marine predator search behaviour.
    “... that do not correspond to valid probability distributions. We demonstrate how this led to overwhelming...”
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  8. 6088
    Homeostatic tissue responses in skin biopsies from NOMID patients with constitutive overproduction of IL-1β.
    “... production. Treatment with anakinra led to the disappearance of neutrophils, but CD3(+) T cells and HLA-DR...”
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  9. 6089
    Involvement of dynamin-related protein 1 in free fatty acid-induced INS-1-derived cell apoptosis.
    “...-expression of DRP-1 led to aggravated INS-1-derived cell apoptosis triggered by FFAs. In contrast, dominant...”
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  10. 6090
    Effect of transmission reduction by insecticide-treated bednets (ITNs) on antimalarial drug resistance in western Kenya.
    “.... These results suggest that increased antifolate drug use due to drug policy change likely led to the high...”
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  11. 6091
    Camphene, a plant-derived monoterpene, reduces plasma cholesterol and triglycerides in hyperlipidemic rats independently of HMG-CoA reductase activity.
    “...) and 34.5% of triglycerides (p<0.001). Treatment of HepG2 cells with camphene led to a decrease in cellular...”
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  12. 6092
    Clinician-scientists in Canada: barriers to career entry and progress.
    “...-clinical PhDs. However, clinician-scientist-led grants funded under CIHR's Clinical thematic area decreased...”
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  13. 6093
    PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship between two genes involved in neuroblastoma.
    “... in the great majority of primary NB samples and cell lines. These observations led us to test the hypothesis...”
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  14. 6094
    Improving rational treatment of malaria: perceptions and influence of RDTs on prescribing behaviour of health workers in southeast Nigeria.
    “...% of RDT-negative results.<h4>Conclusions/significance</h4>RDT-supported malaria diagnosis may have led...”
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  15. 6095
    Crocodiles in the Sahara desert: an update of distribution, habitats and population status for conservation planning in Mauritania.
    “... combined with human persecution led to local extinction. Knowledge on distribution, occupied habitats...”
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  16. 6096
    Psyllium supplementation in adolescents improves fat distribution & lipid profile: a randomized, participant-blinded, placebo-controlled, crossover trial.
    “... tolerance. Fibre supplementation led to a 4% reduction in android fat to gynoid fat ratio (p = 0.019...”
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  17. 6097
    A systematic review of comparative efficacy of treatments and controls for depression.
    “..., antidepressants led to greater symptom reduction compared to placebo among both unpublished FDA data and published...”
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  18. 6098
    Groundtruthing next-gen sequencing for microbial ecology-biases and errors in community structure estimates from PCR amplicon pyrosequencing.
    “... has transformed microbial ecology research and led to the observation that many communities contain a...”
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  19. 6099
    Nodes of ranvier and paranodes in chronic acquired neuropathies.
    “... by blind evaluators led to correct diagnosis in 70 ± 4% of the cases. This study characterizes...”
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  20. 6100
    Neutrophils reduce the parasite burden in Leishmania (Leishmania) amazonensis-infected macrophages.
    “... predominance of macrophages harboring a high number of amastigotes and very few neutrophils. These findings led...”
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