Sequential Ras/MAPK and PI3K/AKT/mTOR pathways recruitment drives basal extrusion in the prostate-like gland of Drosophila

por Amandine Rambur, Corinne Lours-Calet, Claude Beaudoin, Julio Buñay, Marine Vialat, Vincent Mirouse, Amalia Trousson, Yoan Renaud, Jean-Marc A. Lobaccaro, Silvère Baron, Laurent Morel, Cyrille de Joussineau
Publicado 2020

Inhibition of mTORC1 by lncRNA H19 via disrupting 4E-BP1/Raptor interaction in pituitary tumours

por Ze Rui Wu, Lichong Yan, Yan Ting Liu, Lei Cao, Yu Hang Guo, Yong Zhang, Hong Yao, Lin Cai, Han Bing Shang, Wei Wei Rui, Gang Yang, Xiao Biao Zhang, Hao Tang, Yu Wang, Jin Yan Huang, Yong Xu Wei, Wei Guo Zhao, Bing Su, Zhe Bao Wu
Publicado 2018

The ratio of T790M to EGFR-activating mutation predicts response of osimertinib in 1st or 2nd generation EGFR-TKI-refractory NSCLC

por Motohiro Tamiya, Akihiro Tamiya, Norio Okamoto, Yoshihiko Taniguchi, Kazumi Nishino, Shinji Atagi, Tomonori Hirashima, Fumio Imamura, Toru Kumagai, Hidekazu Suzuki
Publicado 2021

Nanoparticle-mediated tumor cell expression of mIL-12 via systemic gene delivery treats syngeneic models of murine lung cancers

por Hye-Hyun Ahn, Christine Carrington, Yizong Hu, Heng-wen Liu, Christy Ng, Hwanhee Nam, Andrew Park, Catherine Stace, Will West, Hai-Quan Mao, Martin G. Pomper, Christopher G. Ullman, Il Minn
Publicado 2021

Author Correction: P53 and mTOR signalling determine fitness selection through cell competition during early mouse embryonic development

por Sarah Bowling, Aida Di Gregorio, Margarida Sancho, Sara Pozzi, Marieke Aarts, Massimo Signore, Michael D. Schneider, Juan Pedro Martinez-Barbera, Jesús Gil, Tristan A. Rodríguez
Publicado 2018

Discovery and Development of a Novel mPGES-1/5-LOX Dual Inhibitor LFA-9 for Prevention and Treatment of Chronic Inflammatory Diseases

por Yarla NS, Pathuri G, Gali H, Terzyan S, Panneerselvam J, Chandrakesan P, Scotti MT, Houchen C, Madka V, Rao CV
Publicado 2020

Functional characterization of a loss-of-function mutant I324M of arginine vasopressin receptor 2 in X-linked nephrogenic diabetes insipidus

por Lixia Wang, Weihong Guo, Chunyun Fang, Wenli Feng, Yumeng Huang, Xiaona Zhang, Ming Liu, Jingqiu Cui
Publicado 2021

Multiscale-omic assessment of EWSR1-NFATc2 fusion positive sarcomas identifies the mTOR pathway as a potential therapeutic target

por Nathan D. Seligson, Richard D. Maradiaga, Colin M. Stets, Howard M. Katzenstein, Sherri Z. Millis, Alan Rogers, John L. Hays, James L. Chen
Publicado 2021

Age as a risk factor for acute mountain sickness upon rapid ascent to 3,700 m among young adult Chinese men

por Tang XG, Zhang JH, Qin J, Gao XB, Li QN, Yu J, Ding XH, Huang L
Publicado 2014

Daunorubicin-Loaded CdTe QDs Conjugated with Anti-CD123 mAbs: A Novel Delivery System for Myelodysplastic Syndromes Treatment

por Guo D, Xu P, Chen D, Wang L, Zhu Y, Zuo Y, Chen B
Publicado 2020

Identification of key genes, pathways and miRNA/mRNA regulatory networks of CUMS-induced depression in nucleus accumbens by integrated bioinformatics analysis

por Ma K, Zhang HX, Wei GH, Dong ZF, Zhao HJ, Han XC, Song XB, Zhang HL, Zong X, Baloch Z, Wang SJ
Publicado 2019

Correspondence Regarding “Tolerability of Coronavirus Disease 2019 Vaccines BNT162b2 and mRNA-1273 in Patients With Thymic Epithelial Tumors”

por Kazuki Takada, MD, PhD, Shinkichi Takamori, MD, PhD, Naoko Miura, MD, PhD, Yasunori Shikada, MD, PhD, Mototsugu Shimokawa, PhD
Publicado 2021

Styrene maleic acid micelles as a nanocarrier system for oral anticancer drug delivery – dual uptake through enterocytes and M-cells

por Parayath NN, Nehoff H, Müller P, Taurin S, Greish K
Publicado 2015

Penerapan Metode Lean Six Sigma untuk Meningkatkan Keakuratan Jadwal Perawatan Pesawat CN-295M di Skadron Teknik 021

por Retno Pratiwi, Toto Hardiyanto Subagyo, Dinar Dewi Kania, Prasadja Ricardianto
Publicado 2021

LncRNA CASC11 Promotes Hepatocellular Carcinoma Progression via Upregulation of UBE2T in a m6A-Dependent Manner

por Fei Chen, Meijun Li, Liang Wang
Publicado 2021

SIRT1 Promotes M2 Microglia Polarization via Reducing ROS-Mediated NLRP3 Inflammasome Signaling After Subarachnoid Hemorrhage

por Da-Yong Xia, Jin-Long Yuan, Xiao-Chun Jiang, Min Qi, Nian-Sheng Lai, Ling-Yun Wu, Xiang-Sheng Zhang
Publicado 2021

Robust Antibody Levels in Both Diabetic and Non-Diabetic Individuals After BNT162b2 mRNA COVID-19 Vaccination

por Hamad Ali, Hamad Ali, Abdulmohsen Alterki, Abdulmohsen Alterki, Sardar Sindhu, Sardar Sindhu, Barrak Alahmad, Maha Hammad, Salman Al-Sabah, Mohammad Alghounaim, Mohammad H. Jamal, Ali Aldei, Mohammad J. Mairza, Maitham Husain, Sriraman Deverajan, Rasheed Ahmad, Preethi Cherian, Irina Alkhairi, Abdullah Alkandari, Jehad Abubaker, Mohamed Abu-Farha, Fahd Al-Mulla
Publicado 2021

Knockdown of anion exchanger 2 suppressed the growth of ovarian cancer cells via mTOR/p70S6K1 signaling

por Li-Jun Zhang, Renquan Lu, Ya-Nan Song, Jian-Yong Zhu, Wei Xia, Miao Zhang, Zhi-Yi Shao, Yan Huang, Yuqi Zhou, Hongqin Zhang, Lin Guo, Meiqin Zhang, Hong Zhang
Publicado 2017

Translation, but not transfection limits clinically relevant, exogenous mRNA based induction of alpha-4 integrin expression on human mesenchymal stem cells

por Adam Nowakowski, Anna Andrzejewska, Johannes Boltze, Franziska Nitzsche, Li-li Cui, Jukka Jolkkonen, Piotr Walczak, Barbara Lukomska, Miroslaw Janowski
Publicado 2017

Aseismic transient during the 2010–2014 seismic swarm: evidence for longer recurrence of M ≥ 6.5 earthquakes in the Pollino gap (Southern Italy)?

por Daniele Cheloni, Nicola D’Agostino, Giulio Selvaggi, Antonio Avallone, Gianfranco Fornaro, Roberta Giuliani, Diego Reale, Eugenio Sansosti, Pietro Tizzani
Publicado 2017