Discovery of a small molecule inhibitor of cullin neddylation that triggers ER stress to induce autophagy

por Yanan Li, Chaorong Wang, Tiantian Xu, Peichen Pan, Qing Yu, Lei Xu, Xiufang Xiong, Tingjun Hou, Sunliang Cui, Yi Sun
Publicado 2021

Targeting TBK1 Attenuates LPS-Induced NLRP3 Inflammasome Activation by Regulating of mTORC1 Pathways in Trophoblasts

por Sohee Lee, Jiha Shin, Jong-Seok Kim, Jongdae Shin, Jongdae Shin, Sung Ki Lee, Sung Ki Lee, Hwan-Woo Park
Publicado 2021

Functional Amino Acids and Autophagy: Diverse Signal Transduction and Application

por Chunchen Liu, Linbao Ji, Jinhua Hu, Ying Zhao, Lee J. Johnston, Xiujun Zhang, Xi Ma
Publicado 2021

Intracellular Staphylococcus aureus Infection Decreases Milk Protein Synthesis by Preventing Amino Acid Uptake in Bovine Mammary Epithelial Cells

por Yuhao Chen, Yuhao Chen, Yuze Ma, Qiang Ji, Xiaoru Yang, Xue Feng, Ruiyuan Yao, Xiaoou Cheng, Tingting Li, Yanfeng Wang, Zhigang Wang
Publicado 2021

Chronic Activation of AMPK Induces Mitochondrial Biogenesis through Differential Phosphorylation and Abundance of Mitochondrial Proteins in <i>Dictyostelium discoideum</i>

por Malgorzata Heidorn-Czarna, Herbert-Michael Heidorn, Sanjanie Fernando, Oana Sanislav, Wieslawa Jarmuszkiewicz, Rupert Mutzel, Paul R. Fisher
Publicado 2021

Azoxystrobin Impairs Neuronal Migration and Induces ROS Dependent Apoptosis in Cortical Neurons

por Jieun Kang, Kausik Bishayee, Sung-Oh Huh
Publicado 2021

mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Müller glia

por Soyeon Lim, You-Joung Kim, Sooyeon Park, Ji-heon Choi, Young Hoon Sung, Katsuhiko Nishimori, Zbynek Kozmik, Han-Woong Lee, Jin Woo Kim
Publicado 2021

Possible Involvement of the Nutrient and Energy Sensors mTORC1 and AMPK in Cell Fate Diversification in a Non-Metazoan Organism

por Julian D. Gross, Catherine J. Pears
Publicado 2021

Activation of ERK and p38 Reduces AZD8055-Mediated Inhibition of Protein Synthesis in Hepatocellular Carcinoma HepG2 Cell Line

por Ha-yeon Jee, Yoon-Gyeong Lee, Sol Lee, Rosalie Elvira, Hye-eun Seo, Ji-Yeon Lee, Jaeseok Han, Kyungho Lee
Publicado 2021