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381por Ingmar Rieger, Vasileia Tsintari, Mathis Overkamp, Falko Fend, Charles D. Lopez, Marcus M. Schittenhelm, Kerstin M. Kampa-Schittenhelm, Kerstin M. Kampa-Schittenhelm“... tumor suppressor, that functions through both p53-dependent as well as p53-independent mechanisms...”
Publicado 2021
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382“... promise in clinical therapy. Increasing evidences have shown that p53 and its target genes play important...”
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383por Helge M. Magnussen, Syed F. Ahmed, Gary. J. Sibbet, Ventzislava A. Hristova, Koji Nomura, Andreas K. Hock, Lewis J. Archibald, Andrew G. Jamieson, David Fushman, Karen H. Vousden, Allan M. Weissman, Danny T. Huang“...p53 is an important tumor suppressor protein which is regulated by the E3 ubiquitin ligase MDM2...”
Publicado 2020
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384por Burhan Uyanik, Anastasia R. Goloudina, Aamir Akbarali, Bogdan B. Grigorash, Alexey V. Petukhov, Sunil Singhal, Evgeniy Eruslanov, Jeanne Chaloyard, Lisa Lagorgette, Tarik Hadi, Ekaterina V. Baidyuk, Hiroyasu Sakai, Lino Tessarollo, Bernhard Ryffel, Sharlyn J. Mazur, Frederic Lirussi, Carmen Garrido, Ettore Appella, Oleg N. Demidov“...Wip1 is a negative regulator of the tumor suppressor p53 and is overexpressed in several human...”
Publicado 2021
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385por Liping Zhong, Yong Huang, Jian He, Nuo Yang, Banghao Xu, Yun Ma, Junjie Liu, Chao Tang, Chengpiao Luo, Pan Wu, Zongqiang Lai, Yu Huo, Tao Lu, Dongni Huang, Wenlin Gong, Lu Gan, Yiqun Luo, Zhikun Zhang, Xiyu Liu, Yongxiang Zhao“... approach to induce efficient loss-of-function mutations of Pten and p53 genes for rapid modeling primary...”
Publicado 2021
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386por Dennis M. Timmerman, Thomas F. Eleveld, Ad J. M. Gillis, Carlijn C. Friedrichs, Sanne Hillenius, Tessa L. Remmers, Sruthi Sriram, Leendert H. J. Looijenga“..., suggesting a contributing role for P53, even in NCCIT, in which P53 had been reported to be non-functional...”
Publicado 2021
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387por Marco Gerling, Rainer Glauben, Jens K Habermann, Anja A Kühl, Christoph Loddenkemper, Hans-Anton Lehr, Martin Zeitz, Britta Siegmund“... expression of p53, beta-catenin and Ki67 was measured to further characterize murine tumor development...”
Publicado 2011
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388por Sheng-Yen Huang, Chih-Yeu Fang, Chung-Chun Wu, Ching-Hwa Tsai, Su-Fang Lin, Jen-Yang Chen“... and H₂O₂ treatment, suggesting ROS mediate EBV reactivation. The p53 was essential for EBV reactivation...”
Publicado 2013
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389por Begoña Porteiro, Marcos F. Fondevila, Teresa C. Delgado, Cristina Iglesias, Monica Imbernon, Paula Iruzubieta, Javier Crespo, Amaia Zabala-Letona, Johan Fernø, Bárbara González-Terán, Nuria Matesanz, Lourdes Hernández-Cosido, Miguel Marcos, Sulay Tovar, Anxo Vidal, Julia Sánchez-Ceinos, Maria M. Malagon, Celia Pombo, Juan Zalvide, Arkaitz Carracedo, Xabier Buque, Carlos Dieguez, Guadalupe Sabio, Miguel López, Patricia Aspichueta, María L. Martínez-Chantar, Ruben Nogueiras“...p53 regulates lipid metabolism and fatty acid oxidation, and its inactivation promotes diet-induced...”
Publicado 2017
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390por Yi Wen Kong, Erik C. Dreaden, Sandra Morandell, Wen Zhou, Sanjeev S. Dhara, Ganapathy Sriram, Fred C. Lam, Jesse C. Patterson, Mohiuddin Quadir, Anh Dinh, Kevin E. Shopsowitz, Shohreh Varmeh, Ömer H. Yilmaz, Stephen J. Lippard, H. Christian Reinhardt, Michael T. Hemann, Paula T. Hammond, Michael B. Yaffe“...Cell cycle checkpoint kinase, MK2, is in synthetic relationship with p53 in the DNA damage response...”
Publicado 2020
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391por Gorka Larrinaga, Julio Calvete-Candenas, Jon Danel Solano-Iturri, Ana M. Martín, Angel Pueyo, Caroline E. Nunes-Xavier, Rafael Pulido, Juan F. Dorado, José I. López, Javier C. Angulo“... with radical cystectomy and other clinical and histopathological parameters including p53, markers of immune...”
Publicado 2021
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392“.../mouse/day dose for 15 days resulted in increased expression of tumor suppressor proteins P53/p21...”
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393por Jean-Luc Perfettini, Roberta Nardacci, Mehdi Bourouba, Frédéric Subra, Laurent Gros, Claire Séror, Gwenola Manic, Filippo Rosselli, Alessandra Amendola, Peggy Masdehors, Luciana Chessa, Giuseppe Novelli, David M Ojcius, Jan Konrad Siwicki, Magdalena Chechlinska, Christian Auclair, José R Regueiro, Hugues de Thé, Marie-Lise Gougeon, Mauro Piacentini, Guido Kroemer“... phosphorylation of p53 on serine 46, thereby causing p53 dependent apoptosis. Both wild type HIV-1 and an HIV-1...”
Publicado 2008
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394“... and translation factors. Knockout of p53 largely phenocopies ARF loss, with increased protein synthesis...”
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395por Ho Joong Sung, Wenzhe Ma, Matthew F Starost, Cory U Lago, Philip K Lim, Michael N Sack, Ju-Gyeong Kang, Ping-yuan Wang, Paul M Hwang“..., by decreasing ambient oxygen exposure, we report a ∼50% increase in the median tumor-free survival time of p53...”
Publicado 2011
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396“... to be mediated by reactive oxygen species via p53 pathway, through which most of the anticancer drugs trigger...”
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397por Li-na Wu, Xiao-wei Wei, Yang Fan, Jia-ning Miao, Li-li Wang, Yi Zhang, Di Wu, Zheng-wei Yuan“... different cell types. We also investigated the expression of p53, a molecule that is downstream of 14-3-3ζ...”
Publicado 2013
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398por Al Refaey,Heba R., Newairy,Al-Sayeda A., Wahby,Mayssaa M., Albanese,Chris, Elkewedi,Mohamed, Choudhry,Muhammad Umer, Sultan,Ahmed S.“...)-mediated apoptotic cell death, using two different p53 statuses (HepG2 and Hep3B) and one non-tumorigenic...”
Publicado 2021
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400por Kiyoto Kamagata, Nanako Iwaki, Milan Kumar Hazra, Saori Kanbayashi, Trishit Banerjee, Rika Chiba, Seiji Sakomoto, Virginie Gaudon, Bertrand Castaing, Hiroto Takahashi, Michiko Kimura, Hiroyuki Oikawa, Satoshi Takahashi, Yaakov Levy“... of different sizes, structures, and oligomeric states were examined in host p53 liquid droplets. Recruitment...”
Publicado 2021
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