Mostrando 521 - 540 Resultados de 899 Para Buscar '"p53"', tiempo de consulta: 0.08s Limitar resultados
  1. 521
    Pramlintide, an antidiabetic, is antineoplastic in colorectal cancer and synergizes with conventional chemotherapy
    “... colorectal cancer cell lines expressing wild-type and mutant p53.Materials and methods: The antiproliferative...”
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  2. 522
    Apoptosis and oxidative stress as relevant mechanisms of antitumor activity and genotoxicity of ZnO-NPs alone and in combination with N-acetyl cysteine in tumor-bearing mice
    por El-Shorbagy HM, Eissa SM, Sabet S, El-Ghor AA
    Publicado 2019
    “... carcinoma (ESC) bearing mice by measuring their effect on the expression levels of P53, Bax and Bcl2 genes...”
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  3. 523
    The potential role of As-sumo-1 in the embryonic diapause process and early embryo development of Artemia sinica.
    “... and the location of As-sumo-1 were investigated. SUMO-1, p53, Mdm2, Caspase-1, Cyclin B and Cyclin E proteins were...”
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  4. 524
    TRIB2 confers resistance to anti-cancer therapy by activating the serine/threonine protein kinase AKT
    “... and the subsequent FOXO inactivation and disruption of p53 function....”
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  5. 525
    Exploiting interconnected synthetic lethal interactions between PARP inhibition and cancer cell reversible senescence
    “... that sustained PARP inhibition promotes a reversible p53-independent senescence, and that PARP inhibition...”
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  6. 526
    miR-34 activity is modulated through 5′-end phosphorylation in response to DNA damage
    “...MiR-34 is a tumour suppressor microRNA known to be upregulated by p53 after DNA damage and plays a...”
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  7. 527
    TAp73-induced phosphofructokinase-1 transcription promotes the Warburg effect and enhances cell proliferation
    “...TAp73 is a structural homolog of the tumor suppressor p53. Here they show that TAp73 is critical...”
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  8. 528
    Deletion of Topoisomerase 1 in excitatory neurons causes genomic instability and early onset neurodegeneration
    “... onset neurodegeneration that is partially dependent on p53/PARP1 activation and NAD+ depletion....”
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  9. 529
    ASPP proteins discriminate between PP1 catalytic subunits through their SH3 domain and the PP1 C-tail
    “..., such as ASPP (apoptosis-stimulating protein of p53) to achieve selective targeting. Here authors solved...”
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  10. 530
    Structural basis for recognition of 53BP1 tandem Tudor domain by TIRR
    “...The p53-binding protein 1 (53BP1) regulates the choice of the DNA double-strand break repair...”
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  11. 531
    DsbA-L mediated renal tubulointerstitial fibrosis in UUO mice
    “... activation of Smad3 and p53, which result in modulation of CTGF, a regulator of kidney fibrosis....”
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  12. 532
    Comprehensive review of fetal adenocarcinoma of the lung
    “.... H-FLAC overexpresses p53. These tumors have a very low frequency of mutations in KRAS and EGFR...”
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  13. 533
    Stress Driven Discovery of Natural Products From Actinobacteria with Anti-Oxidant and Cytotoxic Activities Including Docking and ADMET Properties
    “... by upregulation of P53 and BAX while downregulation of BCL-2 expression, indicating that MVL is following...”
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  14. 534
    EXPERIMENTAL MODELING OF APOPTOSIS UNDER CONDITIONS OF STABLE STRONTIUM EXPOSURE
    “...95 and p53 apoptosis markers was performed by flow cytometry using labeled monoclonal antibodies.In...”
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  15. 535
    Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure
    “... to heart failure via single-cell transcriptomics, establishing a key role for p53 signalling....”
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  16. 536
    ZNF768 links oncogenic RAS to cellular senescence
    “... proliferation and causes cellular senescence ZNF768 binds and represses p53 and its overexpression suffices...”
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  17. 537
    MULHERES NO BRASIL: PERSPECTIVAS DE EDUCAÇÃO PARA A IGUALDADE
    por Raquel Villardi
    Publicado 2019
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  18. 538
    A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing
    “...CRISPR-Cas9 gene editing can induce a p53 mediated damage response. Here the authors investigate...”
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  19. 539
    Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy
    “...Pineoblastoma is a rare pediatric cancer. Here, the authors present inactivation of Rb plus p53 via...”
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  20. 540
    PRMT5 is essential for B cell development and germinal center dynamics
    “... pathways to prevent death of immature B cells, yet modulates, in p53-independent manners, the survival...”
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