Mostrando 81 - 100 Resultados de 899 Para Buscar '"p53"', tiempo de consulta: 0.21s Limitar resultados
  1. 81
    Mechanical cell competition kills cells via induction of lethal p53 levels
    “... of tumour suppressor p53 in the compacted cells, causing cell death....”
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  2. 82
    Mitochondrial uncoupling reveals a novel therapeutic opportunity for p53-defective cancers
    “...Several challenges are involved in direct targeting of mutant p53, while targeting altered fitness...”
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  3. 83
    Olig2 regulates p53-mediated apoptosis, migration and invasion of melanoma cells
    “... cells and tissues. Reduction of Olig2 increased apoptosis in melanoma cells by increasing p53 level...”
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  4. 84
    Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels
    “...Some p53 mutants promote invasive migration of cancer cells and metastasis of tumours in vivo...”
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  5. 85
    CD44 expression in intestinal epithelium and colorectal cancer is independent of p53 status.
    “.... Previous data indicate that CD44 is a direct target of p53-mediated transcriptional repression in breast...”
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  6. 86
    Critical roles of p53 in epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma cells.
    “... in curing HCC is its high metastasis potential. Alteration of p53 is the most frequent genetic change found...”
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  7. 87
    Predicted functions of MdmX in fine-tuning the response of p53 to DNA damage.
    “...Tumor suppressor protein p53 is regulated by two structurally homologous proteins, Mdm2 and MdmX...”
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  8. 88
    Cooperativity dominates the genomic organization of p53-response elements: a mechanistic view.
    por Yongping Pan, Ruth Nussinov
    Publicado 2009
    “...p53-response elements (p53-REs) are organized as two repeats of a palindromic DNA segment spaced...”
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  9. 89
    Mutation or loss of p53 differentially modifies TGFβ action in ovarian cancer.
    “... Genome Atlas Network identified p53 mutations in 96% of high-grade serous ovarian carcinomas...”
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  10. 90
    Expression of P53 and P63 in Oral Lichen Planus and Oral Lichenoid Lesions
    Materias: “...p53...”
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  11. 91
    Author Correction: Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway
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  12. 92
    The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes
    “...The p53 tumor suppressor is also a regulator of metabolism, but the mechanisms controlling p53...”
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  13. 93
    Positive feedback regulation of p53 transactivity by DNA damage-induced ISG15 modification
    “...The ‘genome guardian’ p53 has a well-established role in suppressing tumour development after DNA...”
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  14. 94
    CENP-A overexpression promotes distinct fates in human cells, depending on p53 status
    “... switch in p53 status in human cell lines. They find the tumor suppressor p53 as a key determinant of how...”
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  15. 95
    A fish-specific transposable element shapes the repertoire of p53 target genes in zebrafish.
    “..., binding sites of the pleiotropic master transcription factor p53 were identified in LINE1, Alu and LTR...”
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  16. 96
    SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53.
    “... of stress-tolerance, multiple homeostatic processes and healthspan, while p53 is a stress-responsive...”
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  17. 97
    Inhibition of cell proliferation and migration through nucleobase-modified polyamidoamine-mediated p53 delivery
    por Han H, Chen W, Yang J, Liang X, Wang Y, Li Q, Yang Y, Li K
    Publicado 2018
    “... for p53 gene delivery to achieve the antitumor effects. Methods and materials: The condensation...”
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  18. 98
    Redox Sensitive Cysteine Residues as Crucial Regulators of Wild-Type and Mutant p53 Isoforms
    Materias: “...p53...”
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  19. 99
    p53-Mediated Radiosensitization of <sup>177</sup>Lu-DOTATATE in Neuroblastoma Tumor Spheroids
    Materias: “...p53...”
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  20. 100
    Expression of Fbxo7 in haematopoietic progenitor cells cooperates with p53 loss to promote lymphomagenesis.
    “..., and these effects were dependent on an intact p53 pathway. Furthermore, increased Fbxo7 levels enhanced...”
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